LOCUS BC050628 1340 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens nucleophosmin (nucleolar phosphoprotein B23,
numatrin), mRNA (cDNA clone MGC:60104 IMAGE:5575414), complete cds.
ACCESSION BC050628
VERSION BC050628.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1340)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1340)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (08-APR-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 110 Row: e Column: 23
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 40353733.
FEATURES Location/Qualifiers
source 1..1340
/db_xref="H-InvDB:HIT000053525"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:60104 IMAGE:5575414"
/tissue_type="Testis, embryonal carcinoma"
/clone_lib="NIH_MGC_92"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1340
/gene="NPM1"
/gene_synonym="B23"
/gene_synonym="NPM"
/db_xref="GeneID:4869"
/db_xref="HGNC:HGNC:7910"
/db_xref="MIM:164040"
CDS 87..971
/gene="NPM1"
/gene_synonym="B23"
/gene_synonym="NPM"
/codon_start=1
/product="nucleophosmin (nucleolar phosphoprotein B23,
numatrin)"
/protein_id="AAH50628.1"
/db_xref="GeneID:4869"
/db_xref="HGNC:HGNC:7910"
/db_xref="MIM:164040"
/translation="MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSL
RTVSLGAGAKDELHIVEAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRL
KCGSGPVHISGQHLVAVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAA
DEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSS
TPRSKGQESFKKQEKTPKTPKGPSSVEDIKAKMQASIEKGGSLPKVEAKFINYVKNCF
RMTDQEAIQDLWQWRKSL"
BASE COUNT 475 a 222 c 307 g 336 t
ORIGIN
1 attccgtcct gcgcggttgt tctctggagc agcgttcttt tatctccgtc cgccttctct
61 cctacctaag tgcgtgccgc cacccgatgg aagattcgat ggacatggac atgagccccc
121 tgaggcccca gaactatctt ttcggttgtg aactaaaggc cgacaaagat tatcacttta
181 aggtggataa tgatgaaaat gagcaccagt tatctttaag aacggtcagt ttaggggctg
241 gtgcaaagga tgagttgcac attgttgaag cagaggcaat gaattacgaa ggcagtccaa
301 ttaaagtaac actggcaact ttgaaaatgt ctgtacagcc aacggtttcc cttgggggct
361 ttgaaataac accaccagtg gtcttaaggt tgaagtgtgg ttcagggcca gtgcatatta
421 gtggacagca cttagtagct gtggaggaag atgcagagtc agaagatgaa gaggaggagg
481 atgtgaaact cttaagtata tctggaaagc ggtctgcccc tggaggtggt agcaaggttc
541 cacagaaaaa agtaaaactt gctgctgatg aagatgatga cgatgatgat gaagaggatg
601 atgatgaaga tgatgatgat gatgattttg atgatgagga agctgaagaa aaagcgccag
661 tgaagaaatc tatacgagat actccagcca aaaatgcaca aaagtcaaat cagaatggaa
721 aagactcaaa accatcatca acaccaagat caaaaggaca agaatccttc aagaaacagg
781 aaaaaactcc taaaacacca aaaggaccta gttctgtaga agacattaaa gcaaaaatgc
841 aagcaagtat agaaaaaggt ggttctcttc ccaaagtgga agccaaattc atcaattatg
901 tgaagaattg cttccggatg actgaccaag aggctattca agatctctgg cagtggagga
961 agtctcttta agaaaatagt ttaaacaatt tgttaaaaaa ttttccgtct tatttcattt
1021 ctgtaacagt tgatatctgg ctgtcctttt tataatgcag agtgagaact ttccctaccg
1081 tgtttgataa atgttgtcca ggttctattg ccaagaatgt gttgtccaaa atgcctgttt
1141 agtttttaaa gatggaactc caccctttgc ttggttttaa gtatgtatgg aatgttatga
1201 taggacatag tagtagcggt ggtcagacat ggaaatggtg gggagacaaa aatatacatg
1261 tgaaataaaa ctcagtattt taataaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1321 aaaaaaaaaa aaaaaaaaaa
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