LOCUS BC050532 4185 bp mRNA linear HUM 11-AUG-2006
DEFINITION Homo sapiens gamma-aminobutyric acid (GABA) B receptor, 1, mRNA
(cDNA clone MGC:57575 IMAGE:5732186), complete cds.
ACCESSION BC050532
VERSION BC050532.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4185)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4185)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (08-APR-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Invitrogen
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 107 Row: h Column: 11
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 11497611.
FEATURES Location/Qualifiers
source 1..4185
/db_xref="H-InvDB:HIT000053479_04"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:57575 IMAGE:5732186"
/tissue_type="Brain, hippocampus"
/clone_lib="NIH_MGC_124"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..4185
/gene="GABBR1"
/gene_synonym="dJ271M21.1.1"
/gene_synonym="dJ271M21.1.2"
/gene_synonym="GABAB(1e)"
/gene_synonym="GABABR1"
/gene_synonym="GABBR1-3"
/gene_synonym="GPRC3A"
/gene_synonym="hGB1a"
/db_xref="GeneID:2550"
/db_xref="HGNC:HGNC:4070"
/db_xref="MIM:603540"
CDS 210..2744
/gene="GABBR1"
/gene_synonym="dJ271M21.1.1"
/gene_synonym="dJ271M21.1.2"
/gene_synonym="GABAB(1e)"
/gene_synonym="GABABR1"
/gene_synonym="GABBR1-3"
/gene_synonym="GPRC3A"
/gene_synonym="hGB1a"
/codon_start=1
/product="gamma-aminobutyric acid (GABA) B receptor, 1"
/protein_id="AAH50532.2"
/db_xref="GeneID:2550"
/db_xref="HGNC:HGNC:4070"
/db_xref="MIM:603540"
/translation="MGPGAPFARVGWPLPLLVVMAAGVAPVWASHSPHLPRPHSRVPP
HPSSERRAVYIGALFPMSGGWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSK
CDPGQATKYLYELLYNDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNR
QRFPTFFRTHPSATLHNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGI
EITFRQSFFSDPAVPVKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLI
GWYADNWFKIYDPSINCTVDEMTEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLT
KRLKRHPEETGGFQEAPLAYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITDQI
YRAMNSSSFEGVSGHVVFDASGSRMAWTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDK
WIGGSPPADQTLVIKTFRFLSQKLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYIQNS
QPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFSLGYGSMFT
KIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIETF
AKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYKGLLLLLGIFLAYETKSVSTEKI
NDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKM
RRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKENRELEKIIAEKEERVSELRHQ
LQSRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSRVHLLYK"
BASE COUNT 966 a 1195 c 1026 g 998 t
ORIGIN
1 ggagagtccg cggtggcggc gacggtggcg agagccgcgg gggccgtagg aagccaacct
61 tccctgcttc tccggggccc tcgccccctc ctccccacaa aatcagggat ggaggcgcct
121 ccccggcacc ctcttagcag ccctccccag gaaaagtgtc ccccctgagc tcctaacgct
181 ccccaacagc tacccctgcc ccccacgcca tggggcccgg ggcccctttt gcccgggtgg
241 ggtggccact gccgcttctg gttgtgatgg cggcaggggt ggctccggtg tgggcctccc
301 actcccccca tctcccgcgg cctcactcgc gggtcccccc gcacccctcc tcagaacggc
361 gcgcagtgta catcggggca ctgtttccca tgagcggggg ctggccaggg ggccaggcct
421 gccagcccgc ggtggagatg gcgctggagg acgtgaatag ccgcagggac atcctgccgg
481 actatgagct caagctcatc caccacgaca gcaagtgtga tccaggccaa gccaccaagt
541 acctatatga gctgctctac aacgacccta tcaagatcat ccttatgcct ggctgcagct
601 ctgtctccac gctggtggct gaggctgcta ggatgtggaa cctcattgtg ctttcctatg
661 gctccagctc accagccctg tcaaaccggc agcgtttccc cactttcttc cgaacgcacc
721 catcagccac actccacaac cctacccgcg tgaaactctt tgaaaagtgg ggctggaaga
781 agattgctac catccagcag accactgagg tcttcacttc gactctggac gacctggagg
841 aacgagtgaa ggaggctgga attgagatta ctttccgcca gagtttcttc tcagatccag
901 ctgtgcccgt caaaaacctg aagcgccagg atgcccgaat catcgtggga cttttctatg
961 agactgaagc ccggaaagtt ttttgtgagg tgtacaagga gcgtctcttt gggaagaagt
1021 acgtctggtt cctcattggg tggtatgctg acaattggtt caagatctac gacccttcta
1081 tcaactgcac agtggatgag atgactgagg cggtggaggg ccacatcaca actgagattg
1141 tcatgctgaa tcctgccaat acccgcagca tttccaacat gacatcccag gaatttgtgg
1201 agaaactaac caagcgactg aaaagacacc ctgaggagac aggaggcttc caggaggcac
1261 cgctggccta tgatgccatc tgggccttgg cactggccct gaacaagaca tctggaggag
1321 gcggccgttc cggcgtgcgc ctggaggact tcaactacaa caaccagacc attaccgacc
1381 aaatctaccg ggcaatgaac tcctcgtcct ttgagggtgt ctctggccat gtggtgtttg
1441 atgccagcgg ctctcggatg gcatggacgc ttatcgagca gcttcagggt ggcagctaca
1501 agaagattgg ctactatgac agcaccaagg atgatctttc ctggtccaaa acagataaat
1561 ggattggagg gtccccccca gctgaccaga ccctggtcat caagacattc cgcttcctgt
1621 cacagaaact ctttatctcc gtctcagttc tctccagcct gggcattgtc ctagctgttg
1681 tctgtctgtc ctttaacatc tacaactcac atgtccgtta tatccagaac tcacagccca
1741 acctgaacaa cctgactgct gtgggctgct cactggcttt agctgctgtc ttccccctgg
1801 ggctcgatgg ttaccacatt gggaggaacc agttcccttt cgtctgccag gcccgcctct
1861 ggctcctggg cctgggcttt agtctgggct acggttccat gttcaccaag atttggtggg
1921 tccacacggt cttcacaaag aaggaagaaa agaaggagtg gaggaagact ctggaaccct
1981 ggaagctgta tgccacagtg ggcctgctgg tgggcatgga tgtcctcact ctcgccatct
2041 ggcagatcgt ggaccctctg caccggacca ttgagacatt tgccaaggag gaacctaagg
2101 aagatattga cgtctctatt ctgccccagc tggagcattg cagctccagg aagatgaata
2161 catggcttgg cattttctat ggttacaagg ggctgctgct gctgctggga atcttccttg
2221 cttatgagac caagagtgtg tccactgaga agatcaatga tcaccgggct gtgggcatgg
2281 ctatctacaa tgtggcagtc ctgtgcctca tcactgctcc tgtcaccatg attctgtcca
2341 gccagcagga tgcagccttt gcctttgcct ctcttgccat agttttctcc tcctatatca
2401 ctcttgttgt gctctttgtg cccaagatgc gcaggctgat cacccgaggg gaatggcagt
2461 cggaggcgca ggacaccatg aagacagggt catcgaccaa caacaacgag gaggagaagt
2521 cccggctgtt ggagaaggag aaccgtgaac tggaaaagat cattgctgag aaagaggagc
2581 gtgtctctga actgcgccat caactccagt ctcggcagca gctccgctcc cggcgccacc
2641 caccgacacc cccagaaccc tctgggggcc tgcccagggg accccctgag ccccccgacc
2701 ggcttagctg tgatgggagt cgagtgcatt tgctttataa gtgagggtag ggtgagggag
2761 gacaggccag tagggggagg gaaagggaga ggggaagggc aggggactca ggaagcaggg
2821 ggtccccatc cccagctggg aagaacatgc tatccaatct catctcttgt aaatacatgt
2881 ccccctgtga gttctgggct gatttgggtc tctcatacct ctgggaaaca gacctttttc
2941 tctcttactg cttcatgtaa ttttgtatca cctcttcaca atttagttcg tacctggctt
3001 gaagctgctc actgctcaca tgctgcctcc tcagcagcct cactgcatct ttctcttccc
3061 atgcaacacc ctcttctagt taccacggca acccctgcag ctcctctgcc tttgtgctct
3121 gttcctgtcc agcaggggtc tcccaacaag tgctctttcc accccaaagg ggcctctcct
3181 tttctccact gtcataatct ctttccatct tacttgccct tccatacttt ctcacatgtg
3241 gctccccctg aattttgctt cctttgggag ctcattcctt tcgccaaggc tcacatgctc
3301 cttgcctctg ttctgtgcac tcacgctcag cacacatgca tcctcccctc tcctgcgtgt
3361 gcccactgaa catgctcatg tgtacacacg cttttcccgt atgctttctt catgttcagt
3421 cacatgtgct ctcgggtgcc ctgcattcac agctacgtgt gcccctctca tggtcatggg
3481 tctgcccttg agcgtgtttg ggtaggcatg tgcaatttgt ctagcatgct gagtcatgtc
3541 tttcctattt gcacacgtcc atgtttatcc atgtactttc cctgtgtacc ctccatgtac
3601 cttgtgtact ttcttccctt aaatcatggt attcttctga cagagccata tgtaccctac
3661 cctgcacatt gttatgcact tttccccaat tcatgtttgg tggggccatc cacaccctct
3721 ccttgtcaca gaatctccat ttctgctcag attcccccca tctccattgc attcatgtac
3781 taccctcagt ctacactcac aatcatcttc tcccaagact gctccttttt gttttgtgtt
3841 tttttgaggg gaattaagga aaaataagtg ggggcaggtt tggagagctg cttccagtgg
3901 atagttgatg agaatcctga ccaaaggaag gcacccttga ctgttgggat agacagatgg
3961 acctatgggg tgggaggtgg tgtccctttc acactgtggt gtctcttggg gaaggatctc
4021 cccgaatctc aataaaccag tgaacagtgt gaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
4081 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
4141 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa
//