LOCUS BC050326 3365 bp mRNA linear HUM 16-DEC-2006
DEFINITION Homo sapiens NLR family, pyrin domain containing 4, mRNA (cDNA
clone MGC:48596 IMAGE:4837670), complete cds.
ACCESSION BC050326
VERSION BC050326.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3365)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3365)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (08-APR-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 90 Row: k Column: 10
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 54792746.
FEATURES Location/Qualifiers
source 1..3365
/db_xref="H-InvDB:HIT000053411"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:48596 IMAGE:4837670"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3365
/gene="NLRP4"
/gene_synonym="CLR19.5"
/gene_synonym="FLJ32126"
/gene_synonym="PAN2"
/gene_synonym="PYPAF4"
/gene_synonym="RNH2"
/db_xref="GeneID:147945"
/db_xref="HGNC:HGNC:22943"
/db_xref="MIM:609645"
CDS 97..3081
/gene="NLRP4"
/gene_synonym="CLR19.5"
/gene_synonym="FLJ32126"
/gene_synonym="PAN2"
/gene_synonym="PYPAF4"
/gene_synonym="RNH2"
/codon_start=1
/product="NLR family, pyrin domain containing 4"
/protein_id="AAH50326.1"
/db_xref="GeneID:147945"
/db_xref="HGNC:HGNC:22943"
/db_xref="MIM:609645"
/translation="MAASFFSDFGLMWYLEELKKEEFRKFKEHLKQMTLQLELKQIPW
TEVKKASREELANLLIKHYEEQQAWNITLRIFQKMDRKDLCMKVMRERTGYTKTYQAH
AKQKFSRLWSSKSVTEIHLYFEEEVKQEECDHLDRLFAPKEAGKQPRTVIIQGPQGIG
KTTLLMKLMMAWSDNKIFRDRFLYTFYFCCRELRELPPTSLADLISREWPDPAAPITE
IVSQPERLLFVIDSFEELQGGLNEPDSDLCGDLMEKRPVQVLLSSLLRKKMLPEASLL
IAIKPVCPKELRDQVTISEIYQPRGFNESDRLVYFCCFFKDPKRAMEAFNLVRESEQL
FSICQIPLLCWILCTSLKQEMQKGKDLALTCQSTTSVYSSFVFNLFTPDGAEGPTQQT
QHQLKALCSLAAEGMWTDTFEFCEDDLRRNGVVDADIPALLGTKILLKYGERESSYVF
LHVCIQEFCAALFYLLKSHLDHPHPAVRCVQELLVANFEKARRAHWIFLGCFLTGLLN
KKEQEKLDAFFGFQLSQEIKQQIHQCLKSLGERGNPQGQVDSLAIFYCLFEMQDPAFV
KQAVNLLQEANFHIIDNVDLVVSAYCLKYCSSLRKLCFSVQNVFKKEDEHSSTSDYSL
ICWHHICSVLTTSGHLRELQVQDSTLSESTFVTWCNQLRHPSCRLQKLGINNVSFSGQ
SVLLFEVLFYQPDLKYLSFTLTKLSRDDIRSLCDALNYPAGNVKELALVNCHLSPIDC
EVLAGLLTNNKKLTYLNVSCNQLDTGVPLLCEAMCSPDTVLVYLMLAFCHLSEQCCEY
ISEMLLRNKSVRYLDLSANVLKDEGLKTLCEALKHPDCCLDSLCLVKCFITAAGCEDL
ASALISNQNLKILQIGCNEIGDVGVQLLCRALTHTDCRLEILGLEECGLTSTCCKDLA
SVLTCSKTLQLLNLTLNTLDHTGVVVLCEALRHPECALQVLGLRKTDFDEETQALLTA
EEERNPNLTITDDCDTITRVEI"
BASE COUNT 881 a 804 c 837 g 843 t
ORIGIN
1 ggaggagctg gagaacatag acagggatga ggttttattt atttattgtt cctggtcact
61 gtctctttga ggattggtat ctctgctcca gaaaagatgg cagcctcttt cttctctgat
121 tttggtctta tgtggtatct ggaggagctc aaaaaggagg agttcaggaa atttaaagaa
181 catctcaagc aaatgacttt gcagcttgaa ctcaagcaga ttccctggac tgaggtcaaa
241 aaagcatccc gggaagaact tgcaaacctc ttgatcaagc actatgaaga acaacaagct
301 tggaacataa ccttaagaat ctttcaaaag atggatagaa aggatctctg catgaaggtc
361 atgagggaga gaacaggata cacaaagacc tatcaagctc acgcaaagca gaaattcagc
421 cgcttatggt ccagcaagtc tgtcactgag attcacctat actttgagga ggaagtcaag
481 caagaagaat gtgaccattt ggaccgcctt tttgctccca aggaagctgg gaaacagcca
541 cgtacagtga tcattcaagg accacaagga attggaaaaa cgacactcct gatgaagctg
601 atgatggcct ggtcggacaa caagatcttt cgggataggt tcctgtacac attctatttc
661 tgctgcagag aactgaggga gttgccgcca acgagtttgg ctgacttgat ttccagagag
721 tggcctgacc ccgctgctcc tataacagag atcgtgtctc aaccggagag actcttgttc
781 gtcatcgaca gcttcgaaga gctgcagggc ggcttgaacg aacccgattc ggatctgtgt
841 ggtgacttga tggagaaacg gccggtgcag gtgcttctga gcagtttgct gaggaagaag
901 atgctcccgg aggcctccct gctcatcgct atcaaacccg tgtgcccgaa ggagctccgg
961 gatcaggtga cgatctcaga aatctaccag ccccggggat tcaacgagag tgataggtta
1021 gtgtatttct gctgtttctt caaagacccg aaaagagcca tggaagcctt caatcttgta
1081 agagaaagtg aacagctgtt ttccatatgc caaatcccgc tcctctgctg gatcctgtgt
1141 accagtctga agcaagagat gcagaaagga aaagacctgg ccctgacctg ccagagcact
1201 acctctgtgt actcctcttt cgtctttaac ctgttcacac ctgacggtgc cgagggcccg
1261 actcagcaaa cccagcacca gctgaaggcc ctgtgctccc tggctgcaga gggtatgtgg
1321 acagacacat ttgagttttg tgaagacgac ctccggagaa atggggttgt tgacgctgac
1381 atccctgcgc tgctgggcac caagatactt ctgaagtacg gggagcgtga gagctcctac
1441 gtgttcctcc acgtgtgtat ccaggagttc tgtgccgcct tgttctattt gctcaagagc
1501 caccttgatc atcctcaccc agctgtgaga tgtgtacagg aattgctagt tgccaatttt
1561 gaaaaagcaa ggagagcaca ttggattttt ttggggtgtt ttctaactgg ccttttaaat
1621 aaaaaggaac aagaaaaact ggatgcgttt tttggcttcc aactgtccca agagataaag
1681 cagcaaattc accagtgcct gaagagctta ggggagcgtg gcaatcctca gggacaggtg
1741 gattccttgg cgatatttta ctgtctcttt gaaatgcagg atcctgcctt tgtgaagcag
1801 gcagtgaacc tcctccaaga agctaacttt catattattg acaacgtgga cttggtggtt
1861 tctgcctact gcttaaaata ctgctccagc ttgaggaaac tctgtttttc cgttcaaaat
1921 gtctttaaga aagaggatga acacagctct acgtcggatt acagcctcat ctgttggcat
1981 cacatctgct ctgtgctcac caccagcggg cacctcagag agctccaggt gcaggacagc
2041 accctcagcg agtcgacctt tgtgacctgg tgtaaccagc tgaggcatcc cagctgtcgc
2101 cttcagaagc ttggaataaa taacgtttcc ttttctggcc agagtgttct gctctttgag
2161 gtgctctttt atcagccaga cttgaaatac ctgagcttca ccctcacgaa actctctcgt
2221 gatgacatca ggtccctctg tgatgccttg aactacccag caggcaacgt caaagagcta
2281 gcgctggtaa attgtcacct ctcacccatt gattgtgaag tccttgctgg ccttctaacc
2341 aacaacaaga agctgacgta tctgaatgta tcctgcaacc agttagacac aggcgtgccc
2401 cttttgtgtg aagccatgtg cagcccagac acggtcctgg tatacctgat gttggctttc
2461 tgccacctca gcgagcagtg ctgcgaatac atctctgaaa tgcttctgcg taacaagagc
2521 gtgcgctatc tagacctcag tgccaatgtc ctgaaggacg aaggactgaa aactctctgc
2581 gaggccttga aacatccgga ctgctgcctg gattcactgt gtttggtaaa atgttttatc
2641 actgctgctg gctgtgaaga cctcgcctct gctctcatca gcaatcaaaa cctgaagatt
2701 ctgcaaattg ggtgcaatga aatcggagat gtgggtgtgc agctgttgtg tcgggctctg
2761 acgcatacgg attgccgctt agagattctt gggttggaag aatgtgggtt aacgagcacc
2821 tgctgtaagg atctcgcgtc tgttctcacc tgcagtaaga ccctgcagct gctcaacctg
2881 accttgaaca ccttggacca cacaggggtg gttgtactct gtgaggccct gagacaccca
2941 gagtgtgccc tgcaggtgct cgggctgaga aaaactgatt ttgatgagga aacccaggca
3001 ctgctgacgg ctgaggaaga gagaaatcct aacctgacca tcacagacga ctgtgacaca
3061 atcacaaggg tagagatctg attgcgagga acctgggctc tgactcgaac acctgcaaag
3121 gacagggact gggaccgtta cttacatgac actgcaccca ggagatacaa atcattgaca
3181 ctctgagttg tgagatttct ggcaccccat tcatagattt gatatgatac acgtggtttt
3241 tatgtgctct gtggccttgg atgagtcact gaaaggcctt catggtctct cggtctcaca
3301 aggacctctt aacccctcaa taaagtgtta catttctaaa cattaaaaga aaaaaaaaaa
3361 aaaaa
//