LOCUS BC049369 4276 bp mRNA linear HUM 11-AUG-2006
DEFINITION Homo sapiens protein tyrosine phosphatase-like (proline instead of
catalytic arginine), member b, mRNA (cDNA clone MGC:57203
IMAGE:5286864), complete cds.
ACCESSION BC049369
VERSION BC049369.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4276)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4276)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (28-MAR-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 106 Row: n Column: 8
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 42476153.
FEATURES Location/Qualifiers
source 1..4276
/db_xref="H-InvDB:HIT000099073"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:57203 IMAGE:5286864"
/tissue_type="Brain, hypothalamus"
/clone_lib="NIH_MGC_96"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..4276
/gene="PTPLB"
/db_xref="GeneID:201562"
/db_xref="HGNC:HGNC:9640"
CDS 159..923
/gene="PTPLB"
/codon_start=1
/product="protein tyrosine phosphatase-like (proline
instead of catalytic arginine), member b"
/protein_id="AAH49369.1"
/db_xref="GeneID:201562"
/db_xref="HGNC:HGNC:9640"
/translation="MAAVAATAAAKGNGGGGGRAGAGDASGTRKKKGPGPLATAYLVI
YNVVMTAGWLVIAVGLVRAYLAKGSYHSLYYSIEKPLKFFQTGALLEILHCAIGIVPS
SVVLTSFQVMSRVFLIWAVTHSVKEVQSEDSVLLFVIAWTITEIIRYSFYTFSLLNHL
PYLIKWARYTLFIVLYPMGVSGELLTIYAALPFVRQAGLYSISLPNKYNFSFDYYAFL
ILIMISYIPIFPQLYFHMIHQRRKILSHTEEHKKFE"
BASE COUNT 1196 a 877 c 859 g 1344 t
ORIGIN
1 ctttgccctc agccaagatg gcggctgccg tggaccctgt cccggctccg ccccgcggcc
61 ctggccccgc ctgcccctcg tcccttcctc cgccccctct cctcgcgtag tccggcccga
121 gccgctcgcg ctaggagagc gggcttcggg cacttgacat ggcggcagtg gcggcgactg
181 cagcagcgaa ggggaatggg ggcggcggtg gcagggccgg ggccggggac gccagcggca
241 cgcggaagaa gaagggcccg gggcccctgg ccacggcgta cctggtcatc tacaatgtgg
301 tgatgacagc cgggtggctg gttatagcgg ttggtctggt ccgagcatac ctggctaagg
361 gtagctacca tagcctttat tattcaattg aaaagccttt gaaattcttt caaactggag
421 ccttattgga gattttacat tgtgctatag gaattgttcc atcttctgtt gtcctgactt
481 ctttccaggt gatgtcaaga gtttttctaa tatgggcagt aacacatagc gtcaaagagg
541 tacagagtga agacagtgtc ctcctgtttg ttattgcatg gacgatcacg gaaatcatcc
601 gttactcctt ttatacattc agtctattaa accatctgcc ttacctcatc aaatgggcca
661 ggtacacact tttcattgtg ctgtacccaa tgggagtgtc aggagaactg ctcacaatat
721 atgcagctct gccctttgtc agacaagctg gcctatattc catcagttta cccaacaaat
781 acaatttctc ttttgactac tatgcattcc tgattctaat aatgatctcc tacattccaa
841 tttttcccca gttatacttc cacatgatac accagagaag aaagatcctt tctcatactg
901 aagaacacaa gaaatttgaa tagttcctgc tttctgcacc tcccaccaaa acaaactttt
961 caatgatcaa aaaatgctgc agattttttg agttcccaat acgtttcata gaaaataagt
1021 aagaactatt tttaaaatat tcaaacaaaa ctaaaacaaa aatccagtgt cacatgggcc
1081 tgagatttta ttttagaaaa aggttgttac ataaaacacc ctggccagtt catttcagca
1141 tgctctttca accagaagtt cttaatattt atgatggcac tagaaaggga tttggcattt
1201 tatgtccttc tgtgtccttc atgtatctga tcaatgaaga cctgtaacac taagtacttg
1261 agagttacag tctgaataat gaagtcgtac cagctgaata gcccagcttg cagtatagtt
1321 atgtttcagt ctgcagtgtg tttagcattc ccttgtcaaa gtgcttgact gcatgctgga
1381 aactttgtat ttttgaagcg gcaaactctg ttctctggaa tgctctgaag ttatggctgg
1441 gacctatccc ctcacatcta atgaatgaat tataaaatgt atatgtctat gaagcttcgg
1501 ggtagtgcct gtaatcagaa aacaacttag aacccttttg tttgtttcca attgagtcat
1561 tactgcctgc cactaagaaa cgtgcttgaa tctaataagt atgtgtgtac cgtaaagaat
1621 atatcttatc tggagctcag cctcaatcat gtcttaacaa aatgacaggt ctcagaaagg
1681 gggagctcaa tagctcaaaa gtgacaagtc cttttcacag caccgttctc agaacacctc
1741 tgagtaacgt gtttgccagt agctattctc actgatgcac tgatggccct gaagaagcgg
1801 atccagtcac ataggaaagg aggctgtgtt agtgaaagca catggaaggt gttgctttag
1861 aaaggtagtc aggaaaaaca ttcaggaata gatttataca ccattattgt tttattttta
1921 aattttcatt cactcttctg tttggatact tttgctaatt aacgtcctat gttaatttcc
1981 accaagctat aagtccatag tcagtaaaac attccccttg ggctgtcatg agctaaaagc
2041 agtgtcatct ccgcatgttg gagcagccaa gaaatagttt ggtactaccg acattgtcta
2101 atccatgtca catcctcata caatttaatt gctcaaccat gcatttaaaa ctcctcaaga
2161 aaggattggt actgcaactg taggtaaact gaaaaaaaat aagaaagaaa gagttggatg
2221 aaaatgtgaa agcccaagtt tagatgtgca ttaagtatta aatagcacag tatcttcttc
2281 atggagcctt ttttcctccc ccatcccctg cagctgcctt tttttggggg cagggtgggg
2341 gttgatgttg aactttaaga gtttaaaagt ttagcttatt gagtagttgt catttaaaat
2401 ataattgcga atatcagaaa actcatactg gaaaactaaa tttttttttt ctcttgagac
2461 ggagtctcgc tctgttgccc aggctggagt gcagtggcgc gatctcggct cactgcaagc
2521 tccacctccc gggttcacgc catcctcctg cctcagcctc ctgagtagct gggactacag
2581 gtgcctgcca ccacaccgag ctaatttttt ttgtgttttt agtagagacg gggtttcacc
2641 gtgttagcca ggatggtctt gatctcctga cctcgtgatc cacccgcctc agcctcccaa
2701 agtgctggga ttgcaggcat gagccactgc acccaacccc tggaaaacta aatttttaag
2761 tgcttatttt tatagaagtt tgaaaattta atgcaggcag gtgtgtaata aattattttt
2821 gaattgaaca ttaaaattct gcttcttaaa gtcagcactc aacttggaca tgttgaaatt
2881 agaatctatt cttgtatttg atagacaaaa tatgtgggaa agattttttg catgactttt
2941 ctctcatttt attcttccat aatgtatttc tactataaaa tagaatcaac ttgggttata
3001 tttgtcattt actttgttct gttagatttt ttcagttgtt tttggaaaaa ttctagaaat
3061 caggatgaaa aatgcagctt ttccagggtt gctggactgg gggttttatt tgggcctcct
3121 tattataatt tgtcactact tataaaaaac attctgttgc aaacagtggt gttgcattga
3181 attgaacttt ggcaatgaga acacagcaca cagctccctt ttcaaaaagg gtctcaaccc
3241 cagtgtgtat ttttgtacat caacatttag aatacttatg gcagataagt aaggcatgtc
3301 actgtgtcct tcagtaacct ctctcagtaa ctggtttctt tatccctaac atgaattcat
3361 ttctcctttg aagtcattta ttattttata aattgagaac aaccacacca ccaaatgtca
3421 caccttctta taaagtgtga acaaggaagg tcatgttttt gtgggtattt tgtcagactt
3481 agaggtttca tttcagggca tagtcaaagg catcatcctc ccaactaccc acttgattat
3541 gtatttcaga tccctccgtg ggggccttct tctgacagag aattctttga ggtacgcagt
3601 agtgcttttg tcagcacaga ctgctaatct acatcttgct gcgttctgtt tgctgaggtt
3661 gggcttattc atttaacacg taccaaccat tatccagagg caccatggag agttagtcat
3721 ggaataaagc actgtccttg cagatgaaaa aagtctccag agcagacttc tgacaggaaa
3781 ggtttagatg ctggagagtt gaagaggtgt aagaagagat cgtgccctca tttttcactt
3841 atttttttgg ttattcattt ataataaaag gttggcattg atatggtaca acctgcaaat
3901 tacttgcagt tctgagtttc agataaaaca ttataaaaca ttaaattcaa tacatactgc
3961 tcctttgaaa tttgggtaaa aaattgtaca accgtatata tagtcatttt tgtatttttt
4021 ctatgttgtg aaaaccaaaa ttgtaatttt ataagtcttt gattcactaa aattatataa
4081 tttaaatgta ttttttgtat atttagaaat aaggagtcca gagactacgc ttaactttct
4141 atgcatgcat ttgaaagctg tttttacctg ataatgtagt aataagttgt attcataaaa
4201 tactgatctg tgttgcattt caaaataaac tggtgtgtgc tctgcctgga tttgaaatac
4261 caaaaaaaaa aaaaaa
//