LOCUS BC048769 3047 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens transcription factor 7 (T-cell specific, HMG-box),
mRNA (cDNA clone MGC:47735 IMAGE:6063270), complete cds.
ACCESSION BC048769
VERSION BC048769.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3047)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3047)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (14-MAR-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 82 Row: p Column: 18.
FEATURES Location/Qualifiers
source 1..3047
/db_xref="H-InvDB:HIT000053335"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:47735 IMAGE:6063270"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_72"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3047
/gene="TCF7"
/gene_synonym="MGC47735"
/gene_synonym="TCF-1"
/db_xref="GeneID:6932"
/db_xref="HGNC:HGNC:11639"
/db_xref="MIM:189908"
CDS 197..1351
/gene="TCF7"
/gene_synonym="MGC47735"
/gene_synonym="TCF-1"
/codon_start=1
/product="transcription factor 7 (T-cell specific,
HMG-box)"
/protein_id="AAH48769.1"
/db_xref="GeneID:6932"
/db_xref="HGNC:HGNC:11639"
/db_xref="MIM:189908"
/translation="MPQLDSGGGGAGGGDDLGAPDELLAFQDEGEEQDDKSRDSAAGP
ERDLAELKSSLVNESEGAAGGAGIPGVPGAGAGARGEAEALGREHAAQRLFPDKLPEP
LEDGLKAPECTSGMYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQL
SLYEHFNSPHPTPAPADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSL
MLGSGVPGHPAAIPHPAIVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAF
MLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYP
GWSARDNYGKKKRRSREKHQESTTGGKRNAFGTYPEKAAAPAPFLPMTVL"
BASE COUNT 730 a 990 c 798 g 529 t
ORIGIN
1 cccgccagct cgcggagccg ctctgccccg cgccctagcc cgcgcctgca gcccgcccag
61 gcggagtcag cccgcgctcc gcccgccgcg atccgagctc ggaggttcgg actccgggct
121 cgccgccccc cgggccggct ccgcgccccg cactcccggc gcccagcgcc ccgcgccccg
181 gcgggcggag cgcaccatgc cgcagctgga ctccggcggg ggcggcgcgg gcggcggcga
241 cgacctcggc gcgccggacg agctgctggc cttccaggat gaaggcgagg agcaggacga
301 caagagccgc gacagcgccg ccggtcccga gcgcgacctg gccgagctca agtcgtcgct
361 cgtgaacgag tccgagggcg cggccggcgg cgcagggatc ccgggggtcc cgggggccgg
421 cgccggggcc cgcggcgagg ccgaggctct cgggcgggaa cacgctgcgc agagactctt
481 cccggacaaa cttccagagc ccctggagga cggcctgaag gccccggagt gcaccagcgg
541 catgtacaaa gagaccgtct actccgcctt caatctgctc atgcattacc cacccccctc
601 gggagcaggg cagcaccccc agccgcagcc cccgctgcac aaggccaatc agccccccca
661 cggtgtcccc caactctctc tctacgaaca tttcaacagc ccacatccca cccctgcacc
721 tgcggacatc agccagaagc aagttcacag gcctctgcag acccctgacc tctctggctt
781 ctactccctg acctcaggca gcatggggca gctcccccac actgtgagct ggttcaccca
841 cccatccttg atgctaggtt ctggtgtacc tggtcaccca gcagccatcc cccacccggc
901 cattgtgccc ccctcaggga agcaggagct gcagcccttc gaccgcaacc tgaagacaca
961 agcagagtcc aaggcagaga aggaggccaa gaagccaacc atcaagaagc ccctcaatgc
1021 cttcatgctg tacatgaagg agatgagagc caaggtcatt gcagagtgca cacttaagga
1081 gagcgctgcc atcaaccaga tcctgggccg caggtggcac gcgctgtcgc gagaagagca
1141 ggccaagtac tatgagctgg cccgcaagga gaggcagctg cacatgcagc tatacccagg
1201 ctggtcagcg cgggacaact acgggaagaa gaagaggcgg tcgagggaaa agcaccaaga
1261 atccaccaca ggaggaaaaa gaaatgcatt cggtacttac ccggagaagg ccgctgcccc
1321 agccccgttc cttccgatga cagtgctcta ggctgccccg ggtccccagc tccccaggac
1381 tcaccctcat accatctgct gccccgcttc cccacagaac tgcttactag ccctgcggag
1441 ccggcaccta catccccagg tctctccact gctctcagcc tcccaacccc agggccccca
1501 caggcccccc gcagcaccct gcagagcaca caggtacagc aacaggaatc tcagagacag
1561 gtggcctagc aggcacagga cacctggccg cctccaggag cctaccccct gaaagtgaca
1621 gagacccaga tctcatggaa actggccagg ggtcctgtta acgtcatctc agggtccaga
1681 ccctgaagat ttcagaggct gcagaacttc tgcctgaacc tggggtcatc gattcaaact
1741 gctccaagtg gtgggaatca gatctgtctt gatgtgtcat ctaattaagg gaatcccttg
1801 tacctatggc tgcctgcatc tattctttgt accatctgtc ttgccagcca gaagcctctg
1861 cctccctagc ttttctgcta taggtcagag atgggctgaa ctgagcctag ctaccttctc
1921 tacccatctc ccccatcccc cactgccaca ccctccccat tcagacactt catggaccaa
1981 gaatgagctg gtttgtcaaa caacatgtga gcatggtcac aagcacaaag ctcaagatga
2041 cagctcttct aaggaaatgg agaagctctg tttataaaaa caaaaacaaa accagctgct
2101 actcataagt tggaccagag gaagcccctt actatgatct caggagcttg caagaagcag
2161 gaaggggaat ggaataggtt aagtttaggc ctatcaacct aagcaacaga aataatctga
2221 cactacctta tcaggcaaat tggggagggg agggtgtatc tagctctagt tcaaattatt
2281 tgaaagtgtt ccctgagaaa cccaccagcc taagaagctc tggccccagg cttgtcacta
2341 gcagctgcag tcaacagttc aaagaagtca tggcccaaat ccagtgtgca cccctcccca
2401 ttcacagagc ctttttcaca attccatttc cagttcatct atggcagtcc agccagctcc
2461 tgggcagctt gagagggcaa acccaaaacc tcatgacagc cagagcctgt ctttcagcat
2521 tcagtccgcc tggccggctc cagtttcccc atggggctgc gggacagagg accattacaa
2581 ctagatcaag gagcccagaa aacctccagt agtggacaac aggttttcac catagcctac
2641 gttaacccat ttttgagcca agcttcaacc ctcagccttg aaaaacaagt ctttaattta
2701 atttttgttt tttgcctaaa tccaaagaaa aagggctgtc gggccaggcg cggtggctca
2761 cgcctgtaat cccagcactt tggcaggccg aggcaggtgg atcacctgac gtcagtagtt
2821 tgagaccagc ctggccaaca tggtgaaacc ctgtatctac taaaaataca aaaattagcc
2881 ggacgtggtg gtgcgcgcat gtaatcccag ctactcggga ggctgaggcg gaagaatccc
2941 ttgaacccgg gaggcggagg ttccagtgag ccgaggtggc gctattgcac tccagtctgg
3001 gtaacaggga gactgcatct caaaaaaaaa aaaaaaaaaa aaaaaaa
//