LOCUS BC047752 1471 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens renin, mRNA (cDNA clone MGC:54147 IMAGE:5590211),
complete cds.
ACCESSION BC047752
VERSION BC047752.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1471)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1471)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-MAR-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Invitrogen
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 98 Row: a Column: 21
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 11125774.
FEATURES Location/Qualifiers
source 1..1471
/db_xref="H-InvDB:HIT000053237"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:54147 IMAGE:5590211"
/tissue_type="Ovary, pooled from 3 adults"
/clone_lib="NIH_MGC_125"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1471
/gene="REN"
/db_xref="GeneID:5972"
/db_xref="HGNC:HGNC:9958"
/db_xref="MIM:179820"
CDS 30..1250
/gene="REN"
/codon_start=1
/product="renin"
/protein_id="AAH47752.1"
/db_xref="GeneID:5972"
/db_xref="HGNC:HGNC:9958"
/db_xref="MIM:179820"
/translation="MDGWRRMPRWGLLLLLWGSCTFGLPTDTTTFKRIFLKRMPSIRE
SLKERGVDMARLGPEWSQPMKRLTLGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVV
FDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQ
DIITVGGITVTQMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGV
LKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSV
GSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLFDYVVKCNEGPTLPDI
SFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTE
FDRRNNRIGFALAR"
BASE COUNT 356 a 426 c 373 g 316 t
ORIGIN
1 ctcagagaga gccccagact gagggaagca tggatggatg gagaaggatg cctcgctggg
61 gactgctgct gctgctctgg ggctcctgta cctttggtct cccgacagac accaccacct
121 ttaaacggat cttcctcaag agaatgccct caatccgaga aagcctgaag gaacgaggtg
181 tggacatggc caggcttggt cccgagtgga gccaacccat gaagaggctg acacttggca
241 acaccacctc ctccgtgatc ctcaccaact acatggacac ccagtactat ggcgagattg
301 gcatcggcac cccaccccag accttcaaag tcgtctttga cactggttcg tccaatgttt
361 gggtgccctc ctccaagtgc agccgtctct acactgcctg tgtgtatcac aagctcttcg
421 atgcttcgga ttcctccagc tacaagcaca atggaacaga actcaccctc cgctattcaa
481 cagggacagt cagtggcttt ctcagccagg acatcatcac cgtgggtgga atcacggtga
541 cacagatgtt tggagaggtc acggagatgc ccgccttacc cttcatgctg gccgagtttg
601 atggggttgt gggcatgggc ttcattgaac aggccattgg cagggtcacc cctatcttcg
661 acaacatcat ctcccaaggg gtgctaaaag aggacgtctt ctctttctac tacaacagag
721 attccgagaa ttcccaatcg ctgggaggac agattgtgct gggaggcagc gacccccagc
781 attacgaagg gaatttccac tatatcaacc tcatcaagac tggtgtctgg cagattcaaa
841 tgaagggggt gtctgtgggg tcatccacct tgctctgtga agacggctgc ctggcattgg
901 tagacaccgg tgcatcctac atctcaggtt ctaccagctc catagagaag ctcatggagg
961 ccttgggagc caagaagagg ctgtttgatt atgtcgtgaa gtgtaacgag ggccctacac
1021 tccccgacat ctctttccac ctgggaggca aagaatacac gctcaccagc gcggactatg
1081 tatttcagga atcctacagt agtaaaaagc tgtgcacact ggccatccac gccatggata
1141 tcccgccacc cactggaccc acctgggccc tgggggccac cttcatccga aagttctaca
1201 cagagtttga tcggcgtaac aaccgcattg gcttcgcctt ggcccgctga ggccctctgc
1261 cacccaggca ggccctgcct tcagccctgg cccagagctg gaacactctc tgagatgccc
1321 ctctgcctgg gcttatgccc tcagatggag acattggatg tggagctcct gctggatgcg
1381 tgccctgacc cctgcaccag cccttccctg ctttgaggac aaagagaata aagacttcat
1441 gttcacaaaa aaaaaaaaaa aaaaaaaaaa a
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