LOCUS BC047653 2989 bp mRNA linear HUM 30-JUL-2005
DEFINITION Homo sapiens PH domain and leucine rich repeat protein phosphatase,
mRNA (cDNA clone IMAGE:5259974), partial cds.
ACCESSION BC047653
VERSION BC047653.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2989)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2989)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-MAR-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 90 Row: m Column: 11.
FEATURES Location/Qualifiers
source 1..2989
/db_xref="H-InvDB:HIT000098735"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:5259974"
/tissue_type="Brain, hippocampus"
/clone_lib="NIH_MGC_95"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene <1..2989
/gene="PHLPP"
/gene_synonym="SCOP"
/db_xref="GeneID:23239"
/db_xref="MIM:609396"
CDS <1..1973
/gene="PHLPP"
/gene_synonym="SCOP"
/codon_start=3
/product="PHLPP protein"
/protein_id="AAH47653.1"
/db_xref="GeneID:23239"
/db_xref="MIM:609396"
/translation="FEEIDLSGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLP
EIKCVDLSCNELSEVTLPENLPPKLQELDLTGNPRLVLDHKTLELLNNIRCFKIDQPS
TGDASGAPAVWSHGYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLL
QCTMSDILAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGG
SFTLTSANVGKCQTVLCRNGKPLPLSRSYIMSCEEELKRIKQHKAIITEDGKVNGVTE
STRILGYTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAVRNVPDA
LAAAKKLCTLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGAVPPPSPGIFPPSVN
MVIKDRPSDGLGVPSSSSGMASEISSELSTSEMSSEMGSTASDEPPPGALSENSPAYP
SEQRCMLHPICLSNSFQRQLSSATFSSAFSDNGLDSDDEEPIEGVFTNGSRVEVEVDI
HCSRAKEKEKQQHLLQVPAEASDEGIVISANEDEPGLPRKADFSAVGTIGRRRANGSV
APQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQ
QQQQPPPPPQLQPQLPRHYQLDQLPDYYDTPL"
BASE COUNT 755 a 780 c 734 g 720 t
ORIGIN
1 aatttgaaga aattgatctc agtgggaata agctgaaagc catcccaaca acgatcatga
61 attgcaggcg catgcacacc gtgattgctc actccaactg catcgaggtc tttcccgaag
121 ttatgcagct cccagagatc aagtgtgtgg acctgagctg taatgagcta agtgaagtca
181 cattaccaga aaacctgcct cccaaactgc aggagctaga cctgactgga aacccgcgcc
241 ttgtccttga tcacaaaacc ctggaactac tgaataatat ccgctgtttc aagattgatc
301 agccttctac aggagacgct tccggagccc cagctgtatg gagtcatggt tacactgaag
361 cttcgggggt aaaaaacaag ttgtgtgtcg cagccctgtc ggtgaataac ttctgtgaca
421 accgcgaagc cctgtatggt gtgtttgacg gagaccggaa tgtggaggtg ccctaccttc
481 tccagtgcac tatgagtgac attttggctg aagagctgca aaaaacaaaa aacgaagaag
541 aatacatggt caatacattc attgtcatgc aaaggaaact tggaactgct gggcagaagc
601 ttggtggtgc cgctgtcctt tgtcatatca agcatgaccc tgtggatcca ggaggatcct
661 tcaccttgac ctctgctaat gtgggcaagt gccaaacagt tctctgtcga aatggaaagc
721 cgctgcctct gtccagatct tacatcatga gctgtgaaga agagctgaag aggattaaac
781 agcacaaggc cattatcact gaggatggca aggtgaacgg agtgactgag tccacgcgca
841 tcctgggcta caccttcctc catcccagtg tggtgcctcg cccccacgtg cagtccgtgc
901 tcctgactcc ccaggatgag ttcttcatcc taggcagtaa ggggttgtgg gacagcctgt
961 ccgtcgagga ggccgtggaa gccgtgcgca acgtgcccga tgccctggct gctgccaaga
1021 agctgtgtac cctggcccag agctacggct gccacgacag catcagcgct gtggtggtgc
1081 agctcagtgt cactgaggac agcttctgct gctgcgagct cagcgccggt ggggctgtgc
1141 caccacccag tcctggcatc tttcctccct cagtgaacat ggtgatcaag gatcggccct
1201 cagatgggct gggcgtgccg tcctccagca gcggcatggc ttccgagatt agcagtgagc
1261 tctccacttc tgagatgagc agcgagatgg ggtcaacagc ctccgatgag cccccgcccg
1321 gagccctaag cgagaacagc cctgcctacc ccagtgagca gcgctgcatg ctccacccca
1381 tctgtctgtc caactccttc cagcgccagc tatccagcgc cacgttctct agcgccttct
1441 ccgacaacgg ccttgacagt gacgatgagg agcccatcga gggcgtcttc accaacggca
1501 gccgggtgga ggtggaggtg gacatccact gcagccgggc caaggagaag gagaaacagc
1561 agcacctgct tcaggtgcca gcagaggcca gtgatgaggg cattgtcatc agcgccaacg
1621 aggatgagcc aggtctgccc aggaaggcag acttctctgc cgttgggacc attgggcgcc
1681 ggagggccaa tggctctgtt gcgccccagg aaaggagcca caatgtgata gaggtggcta
1741 cagacgcacc tcttcgaaag cctggaggct attttgctgc cccggctcag ccggatcctg
1801 atgatcagtt tatcataccc ccggagctgg aagaggaggt caaagaaatc atgaagcatc
1861 accaggagca acagcagcag cagcagccgc caccaccccc tcagctccag ccgcagctgc
1921 cgcggcacta ccagctggac cagctgccag attattacga cacgccacta tgacccagcc
1981 gagctgttta acaaataaac taaccacaaa agactgagtt gcaagagtct cccaggctca
2041 cattaaacca ggggttttac tccacatcct tcccacagac actgttccca acctgtcatc
2101 gcagctaatc tgtaggttct ctttctttgg gttatttttt taagtaatca ccactttctt
2161 ctagtgatgc tttaccaata tgatttacat ttgttaactt ctccccctaa catatcagat
2221 atgtaaagac aaagaacaaa aggtttaata tattacagag aaacagttaa tgataatgta
2281 atatttttta aaatggcttt ttgttgtttg tttggaaggc agggcaggct gccgttgcta
2341 aatgatttaa taatattgta attctgtatt tctttggggg gaaaaggctt ttgttttgtt
2401 ttgttttgtt ttgttttgtt tttgtcttga aaataataga catttgtaga atatggagac
2461 taactcctag gagttgcttt actctgtcag gtgacttaag tcactgggat tcactaattt
2521 tctctgagag aacagctgat tgagaatttc cattgtaaat agctcagtgt tgtatagtga
2581 ggcttacgat gttttgtagt cttggcgtaa ggacacagcc caagtaactg acgtttcccc
2641 tccccctccc ctctgaggag cctgcctgcc tcacaactca ccctcacttc actgaatgag
2701 gaggctgagc agctgcagtg tttctgtccg gaggaaatgg atcttaggcc actggacaag
2761 aacctgcacc caagggccct gaacccattt tcctcccctg tcccagcctt cccactttga
2821 cagacacttt taactgtgtt ccttactgct gccacaatca gcatggttgt atagtgcccc
2881 attaggccat ttacataccc agagttatac tcaagcagaa tgcacaaatg gacatgtcat
2941 aatttttgtt acaataaata tgaaatttac aagcaaaaaa aaaaaaaaa
//