LOCUS BC047590 3484 bp mRNA linear HUM 27-OCT-2006
DEFINITION Homo sapiens HEAT repeat containing 4, mRNA (cDNA clone MGC:48595
IMAGE:4837558), complete cds.
ACCESSION BC047590
VERSION BC047590.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3484)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3484)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-MAR-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 90 Row: k Column: 11
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 42558269.
FEATURES Location/Qualifiers
source 1..3484
/db_xref="H-InvDB:HIT000053178"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:48595 IMAGE:4837558"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3484
/gene="HEATR4"
/gene_synonym="MGC48595"
/db_xref="GeneID:399671"
/db_xref="HGNC:HGNC:16761"
CDS 411..3350
/gene="HEATR4"
/gene_synonym="MGC48595"
/codon_start=1
/product="HEAT repeat containing 4"
/protein_id="AAH47590.1"
/db_xref="GeneID:399671"
/db_xref="HGNC:HGNC:16761"
/translation="MVFFSSQYRLHRKSQYLKMAAANLTFSQEVVWQRGLPSIPYSQY
SFDHLYNTNDIIHTPQIRKARPQKPVSFKFLGSSSPLTGDTSLAVKTESSANPEKKLK
KSKPASTVREAPRPLIHHPCMHPDMLGRPPSLDVNLEEREAWLLPPEKEARAWEATVL
EKLNERTARWIQSKRPRRPGASPNKWQSFLRQQYDWSHIRDELTSASDLELLKQLEAE
ETAEFEDQSVILPPQEKKKPELLLPVYYRLPSYFQQAETVEIMPGNKSTEDIHEKTSL
SQPQTQSYFRQVTPRAGKFAYSTDNTFEQEIYFDEVQIIHQIGAKRDQIVLENLNRYN
KQLSKVFPETPEKWSAQAIPEASYRPVQGALRWTALPTPAKDMLLQVGEKDVPIKTRR
LKKQAKSLQEDVTWELVVLRRMLKEWKTAWALIIEWHHETVENLLQSLGDLHDDVRIK
AITTCATAALERPRIATSQRDSDKTIQDLPEVLLPALEAALCDKNAHVRMAAAICQYA
IQSHNPLARNIMQTALLKGNSVDSWAAAQCLALEGTATYPVIKRILHQLFTKKNEDTE
EQSYILLSYLSEKTTLIHTMLAVELNSCQWKNRIVACQAFSRISGNVCLDMKHKLIQL
MWNDWNKEVRRAAAQALGQMSLGKEVHDIIRVKLGQGNSQERVEALYLIGELKLMTAK
LLPSFLHCFSDDFTAVRRAACLAAGALQIRDKMVLECLLNLMQRDPYWKIKAFAIRAL
GQIGQVSPELTDLLLWAIHYEESPGVRLEACRSILALKLQGDRVRDTFLDVLLLENHD
AVLKEMYQTMKILNLGNEGNQEMLQEIKNRIKTLSQKDLLTHKILKLEMVMGKVREEA
KRVYLKPKGEQGPLTLQTLLQETFQDEMVLPRRPSEVCDTEAVIKPVKPRAPNPWLQS
SVPGLTTRSKVRSSLVKDLRTSPEKRIAVGPFRSDYPALYLGKFSERTFFSPIMSSPS
GKKGAHL"
BASE COUNT 972 a 874 c 878 g 760 t
ORIGIN
1 ggatcctaag aaaccaagga aggcttaaga tgcagaacct tgcttctctc tgaggactgc
61 cttttaggag gccatttgga aagtaatttt gaaacactgc tcctttgcca gtatctgaaa
121 ggtgctggat ggtatcagct ggaagatgag gggcaacctg aggtagctga aaaaactttg
181 gattaggtgt caaaagggtg ccaggtctca tctccaggcc tttcctctag gccaggcagt
241 gtggaaggaa gcatttgctg ggacgcagta tgaccaggac ccagaaggga aagacctttc
301 tcccccattg cttctatcag tcactacccc cacgactggg atggggcatg attttaaact
361 actcaaaatt gaaaggcaag taggagtgtg cctctgtctc cagtgtgcct atggtcttct
421 tcagctcaca gtaccgtcta caccgcaaga gccaatattt gaaaatggct gctgcaaacc
481 ttaccttctc tcaggaggtg gtgtggcagc gaggcctgcc cagcattcct tatagccagt
541 acagctttga ccacctctac aataccaatg acatcatcca tactccccag atcaggaagg
601 cccggcctca gaaacctgtt agcttcaagt tcctgggttc ctcaagtccc ttaacaggag
661 acacctccct ggctgtgaag acagaaagct ctgccaatcc cgaaaagaag ctgaagaaat
721 caaagccagc cagcaccgtc cgggaagcac cccgccctct catccatcat ccctgcatgc
781 atccagatat gctgggtcgg ccaccttctc tagatgtgaa cctggaggaa agagaagcct
841 ggcttctgcc tcctgagaag gaggccagag cgtgggaggc cactgtgctg gaaaagctga
901 acgagcgcac agcccgatgg atccagagca agcgtcctcg aaggcctggg gcatccccca
961 acaagtggca gagcttcctg cgccagcagt acgactggag tcacattcgg gatgagctta
1021 cctctgccag tgacctggag ctcctgaaac agctggaggc agaagagaca gcagagtttg
1081 aggatcaaag tgtcatcctg cccccacagg aaaagaagaa gccagaactg ctgcttcccg
1141 tttactacag attgcccagt tacttccaac aagcagagac agttgagatc atgcctggca
1201 acaagagcac tgaggatatc catgaaaaga cgagcctctc ccagccccaa acccagagct
1261 actttcgcca ggtgactccc cgagctggaa agtttgccta ctccacagac aacacctttg
1321 aacaggagat ttactttgat gaagtccaga tcatccacca gattggtgca aagagagacc
1381 agattgtcct ggaaaaccta aatcggtaca acaagcagct atctaaggtc ttccctgaaa
1441 ctccagaaaa gtggagtgcc caggcaattc ctgaagcatc ttacagacct gtgcaaggag
1501 ccctgcgctg gactgctttg cccacccccg ccaaggatat gctgctgcag gtgggtgaga
1561 aggatgtgcc tattaagacc aggagattga agaagcaggc aaaatcactg caggaggatg
1621 tgacctggga actggtggtc ctgcggagga tgctgaagga atggaagact gcctgggctc
1681 tgatcataga gtggcaccat gagacagtag agaacctgct tcagagcttg ggagacctgc
1741 atgatgacgt tcggatcaaa gctatcacca catgtgccac agctgctttg gaacggcccc
1801 ggattgccac cagccagaga gactcagaca agaccatcca ggacttgccg gaggttctac
1861 tgcctgccct agaggctgct ctttgtgaca agaatgccca tgtgcggatg gcagcagcaa
1921 tatgccaata tgccatacag tcacataatc cccttgcccg gaacatcatg cagactgccc
1981 ttctgaaggg taacagtgtg gatagctggg ctgcagctca gtgcttggct ctggaaggta
2041 ctgctactta ccctgtgatt aagaggatcc tccaccagct gtttacaaag aagaatgagg
2101 acactgagga acagtcttat atcctcctga gctatctgag tgagaagaca accctgatac
2161 acaccatgct tgctgtggag ctgaacagct gtcaatggaa gaaccggatt gtggcctgcc
2221 aggctttctc ccggatcagt ggaaatgtct gcttggatat gaaacataag ttgatccagc
2281 tgatgtggaa tgactggaat aaggaagtga ggagagcagc tgcacaggcg cttgggcaaa
2341 tgagcctcgg gaaagaggtg catgacataa tcagggtcaa gctaggtcaa ggaaattccc
2401 aggagcgtgt ggaagctctc tacctgatag gtgagctcaa gcttatgacc gccaagcttc
2461 tcccaagctt cctgcactgc ttctctgatg acttcacagc agttcggcgg gcagcctgtt
2521 tggcagctgg tgccctgcag atccgcgaca agatggtgct tgaatgcctc ctgaacctga
2581 tgcagagaga tccttactgg aaaatcaagg cctttgccat tcgagctttg ggacagattg
2641 ggcaagtaag tcccgagctg acggatcttc tgctctgggc tatccactat gaagagtcac
2701 caggtgtacg gctggaagct tgccgtagca tcctagccct gaaacttcaa ggggaccggg
2761 tcagggacac cttcctagac gtgctgctcc tggagaacca cgatgctgtt ctaaaggaaa
2821 tgtaccagac aatgaagata ctcaacttag gaaatgaagg aaaccaagaa atgcttcagg
2881 agatcaagaa caggattaaa acactaagcc aaaaggactt gctgacacac aaaatactca
2941 agctggagat ggtcatggga aaagtgaggg aggaagcaaa acgtgtttac ttgaaaccca
3001 aaggagaaca aggaccacta acactccaga ctttactcca agaaactttt caggatgaga
3061 tggttcttcc tagaagacct tccgaggttt gtgacactga agcagtgata aagcctgtga
3121 agccccgcgc accaaatccc tggttacaaa gttcagtccc aggcctaacc acacgaagca
3181 aagttcgttc atcacttgtc aaagatctac gcacctcccc cgagaaaagg attgctgtgg
3241 gaccatttag atccgactac ccagctcttt atctgggtaa attctcagag agaacatttt
3301 tttctcccat catgtcttct ccctctggaa agaaaggtgc tcatctctaa gctgaacact
3361 tgtcttactt caagatgcag gaagcagtgg acctggtcac attgggtctt tttaattgat
3421 actgtacaat cttgttgtca ctatgtttat aaagagaaat tatttaacaa aaaaaaaaaa
3481 aaaa
//