LOCUS BC047284 1702 bp mRNA linear HUM 11-AUG-2006
DEFINITION Homo sapiens mitogen-activated protein kinase-activated protein
kinase 5, mRNA (cDNA clone MGC:54058 IMAGE:4997201), complete cds.
ACCESSION BC047284
VERSION BC047284.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1702)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1702)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (28-FEB-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 93 Row: e Column: 17
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21237764.
FEATURES Location/Qualifiers
source 1..1702
/db_xref="H-InvDB:HIT000098493"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:54058 IMAGE:4997201"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_10"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1702
/gene="MAPKAPK5"
/gene_synonym="PRAK"
/db_xref="GeneID:8550"
/db_xref="HGNC:HGNC:6889"
/db_xref="MIM:606723"
CDS 175..1590
/gene="MAPKAPK5"
/gene_synonym="PRAK"
/codon_start=1
/product="mitogen-activated protein kinase-activated
protein kinase 5"
/protein_id="AAH47284.2"
/db_xref="GeneID:8550"
/db_xref="HGNC:HGNC:6889"
/db_xref="MIM:606723"
/translation="MSEESDMDKAIKETSILEEYSINWTQKLGAGISGPVRVCVKKST
QERFALKILLDRPKARNEVRLHMMCATHPNIVQIIEVFANSVQFPHESSPRARLLIVM
EMMEGGELFHRISQHRHFTEKQASQVTKQIALALRHCHLLNIAHRDLKPENLLFKDNS
LDAPVKLCDFGFAKIDQGDLMTPQFTPYYVAPQVLEAQRRHQKEKSGIIPTSPTPYTY
NKSCDLWSLGVIIYVMLCGYPPFYSKHHSRTIPKDMRRKIMTGSFEFPEEEWSQISEM
AKDVVRKLLKVKPEERLTIEGVLDHPWLNSTEALDNVLPSAQLMMDKAVVAGIQQAHA
EQLANMRIQDLKVSLKPLHSVNNPILRKRKLLGTKPKDSVYIHDHENGAEDSNVALEK
LRDVIAQCILPQAGENEDEKLNEVMQEAWKYNRECKLLRDTLQSFSWNGRGFTDKVDR
LKLAEIVKQVIEEQTTSHESQ"
BASE COUNT 493 a 402 c 430 g 377 t
ORIGIN
1 gccgaagcag agccggcgcc ggggtcctca tccccaccgg tcccgagggg cggctgctgc
61 ccgtcgccac gaggcccagg ggcccgagtg ccgagccctt tgctccctcg gccgcgcggg
121 gacagggctg ctgagcagcc tccgcctctc ccggctgtgg gggccccact gagtatgtcg
181 gaggagagcg acatggacaa agccatcaag gaaacttcca ttttagaaga atacagtatc
241 aattggactc agaagctggg agctggaatt agtggtccag ttagagtctg tgtaaagaaa
301 tctactcaag aacggtttgc gctgaaaatt cttcttgatc gtccaaaagc tagaaatgag
361 gtacgtctgc acatgatgtg tgccacacac ccaaacatag ttcagattat tgaagtgttt
421 gctaacagtg tccagtttcc ccatgagtcc agccctaggg cccgactctt aattgtaatg
481 gagatgatgg aagggggaga gctatttcac agaatcagcc agcaccggca ctttacagag
541 aagcaagcca gccaagtaac aaagcagata gctttggctc tgcggcactg tcacttgtta
601 aacattgcgc acagagacct caagcctgaa aatctgcttt ttaaggataa ctctttggat
661 gccccagtga agttgtgtga ctttggattt gccaagattg accaaggtga cttgatgaca
721 ccccagttca ccccttatta tgtagcaccc caggtactgg aggcgcaaag aaggcatcag
781 aaggagaaat ctggcatcat acctacctca ccgacgccct acacttacaa caagagctgt
841 gacttgtggt ccctaggggt gattatctat gtgatgctgt gcggataccc tcctttttac
901 tccaaacacc acagccggac tatcccaaag gatatgcgaa gaaagatcat gacaggcagt
961 tttgagttcc cagaggaaga gtggagtcag atctcagaga tggccaaaga tgttgtgagg
1021 aagctcctga aggtcaaacc ggaggagaga ctcaccatcg agggagtgct ggaccacccc
1081 tggctcaatt ccaccgaggc cctggataat gtgctgcctt ctgctcagct gatgatggac
1141 aaggcagtgg ttgcaggaat ccagcaggct cacgcggaac agttggccaa catgagaatc
1201 caggatctga aagtcagcct caaacccctg cactcagtga acaaccccat tctgcggaag
1261 aggaagttac ttggcaccaa gccaaaggac agtgtctata tccacgacca tgagaatgga
1321 gccgaggatt ccaatgttgc cttggaaaaa ctccgagatg tgattgctca gtgtattctc
1381 ccccaggctg gagagaatga agatgagaaa ctgaatgaag taatgcagga ggcttggaag
1441 tataaccggg aatgcaaact cctaagagat actctgcaga gcttcagctg gaatggtcgt
1501 ggattcacag ataaagtaga tcgactaaaa ctggcagaaa ttgtgaagca ggtgatagaa
1561 gagcaaacca cgtcccacga atcccaataa tgacagcttc agactttgtt tttttaacaa
1621 tttgaaaaat tattctttaa tgtataaagt aattttatgt aaattaataa atcataattt
1681 catttccaaa aaaaaaaaaa aa
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