LOCUS BC045620 6591 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens nucleoporin 214kDa, mRNA (cDNA clone MGC:39489
IMAGE:5268515), complete cds.
ACCESSION BC045620
VERSION BC045620.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6591)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 6591)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (31-JAN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 63 Row: g Column: 10
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 24497442.
FEATURES Location/Qualifiers
source 1..6591
/db_xref="H-InvDB:HIT000098081"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:39489 IMAGE:5268515"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..6591
/gene="NUP214"
/gene_synonym="CAIN"
/gene_synonym="CAN"
/gene_synonym="D9S46E"
/gene_synonym="N214"
/db_xref="GeneID:8021"
/db_xref="HGNC:HGNC:8064"
/db_xref="MIM:114350"
CDS 89..6361
/gene="NUP214"
/gene_synonym="CAIN"
/gene_synonym="CAN"
/gene_synonym="D9S46E"
/gene_synonym="N214"
/codon_start=1
/product="nucleoporin 214kDa"
/protein_id="AAH45620.2"
/db_xref="GeneID:8021"
/db_xref="HGNC:HGNC:8064"
/db_xref="MIM:114350"
/translation="MGDEMDAMIPEREMKDFQFRALKKVRIFDSPEELPKERSSLLAV
SNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVPMKFPIHHLALSC
DNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGGMVIDMKWNPT
VPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVGKQNGTVVQ
YLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPDVVMALL
PKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILARQSD
QINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLMLL
STDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQKLDAS
AAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDS
SKAAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVS
APNIAMKSSFPPSTSAVKVNLSEKFTAAATSTPVSSSQSAPPMSPFSSASKPAASGPL
SHPTPLSAPPSSVPLKSSVLPSPSGRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAK
SLQPAVAEKQGHQWKDSDPVMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKML
RTESDDLHTFLLEIKETTESLHGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLL
YKRPLDPKSEAQLQEIRRLHQYVKFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERET
LFNTLANNREIINQQRKRLNHLVDSLQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLE
SLCNALLKTTIESHTKSLPKVPAKLSPMKQAQLRNFLAKRKTPPVRSTAPASLSRSAF
LSQRYYEDLDEVSSTSSVSQSLESEDARTSCKDDEAVVQAPRHAPVVRTPSIQPSLLP
HAAPFAKSHLVHGSSPGVMGTSVATSASKIIPQGADSTMLATKTVKHGAPSPSHPISA
PQAAAAAALRRQMASQAPAVNTLTESTLKNVPQVVNVQELKNNPATPSTAMGSSVPYS
TAKTPHPVLTPVAANQAKQGSLINSLKPSGPTPASGQLSSGDKASGTAKIETAVTSTP
SASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQGATPSTKESSQPDAFSSGGGSK
PSYEAIPESSPPSGITSASNTTPGEPAASSSRPVAPSGTALSTTSSKLETPPSKLGEL
LFPSSLAGETLGSFSGLRVGQADDSTKPTNKASSTSLTSTQPTKTSGVPSGFNFTAPP
VLGKHTEPPVTSSATTTSVAPPAATSTSSTAVFGSLPVTSAGSSGVISFGGTSLSAGK
TSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFPTLSFGSLLSSATTPSLPMSAGRSTE
EATSSALPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKEPVLAQPAVSNSG
TAASSTSLVALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAISSAGPVAVE
TSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLTNNTATAP
SATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGVFGQTTF
GQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSSSSSF
SFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTAATSGFSFCQASGF
GSSNTGSVFGQAASTGGIVFGQQSSSSSGNVFGSGNTGRGGGFFSGLGGKPSQDAANK
NPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSSGGGSVASQG
FGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGT
AAASAGGFGFGSSSNTTSFGTLASQNAPTFGSLSQQTSGFGTQSSGFSGFGSGTGGFS
FGSNNSSVQGFGGWRS"
BASE COUNT 1591 a 1869 c 1545 g 1586 t
ORIGIN
1 gaggaagttt gctgtcgagc ggcctgggtt ccgtgggcaa ggccgtggga ggcagcgttg
61 gctgcttcga cacactgagg gcggcgcgat gggagacgag atggatgcca tgattcccga
121 gcgggagatg aaggattttc agtttagagc gctaaagaag gtgagaatct ttgactcccc
181 tgaggaattg cccaaggaac gctcgagtct gcttgctgtg tccaacaaat atggtctggt
241 cttcgctggt ggagccagtg gcttgcagat ttttcctact aaaaatcttc ttattcaaaa
301 taaacccgga gatgatccca acaaaatagt tgataaagtc caaggcttgc tagttcctat
361 gaaattccca atccatcacc tggccttgag ctgtgataac ctcacactct ctgcgtgcat
421 gatgtccagt gaatatggtt ccattattgc tttttttgat gttcgcacat tctcaaatga
481 ggctaaacag caaaaacgcc catttgccta tcataagctt ttgaaagatg caggaggcat
541 ggtgattgat atgaagtgga accccactgt cccctccatg gtggcagttt gtctggctga
601 tggtagtatt gctgtcctgc aagtcacgga aacagtgaaa gtatgtgcaa ctcttccttc
661 cacggtagca gtaacctctg tgtgctggag ccccaaagga aagcagctgg cagtgggaaa
721 acagaatgga actgtggtcc agtatcttcc tactttgcag gaaaaaaaag tcattccttg
781 tcctccgttt tatgagtcag atcatcctgt cagagttctg gatgtgctgt ggattggtac
841 ctacgtcttc gccatagtgt atgctgctgc agatgggacc ctggaaacgt ctccagatgt
901 ggtgatggct ctactaccga aaaaagaaga aaagcaccca gagatatttg tgaactttat
961 ggagccctgt tatggcagct gcacggagag acagcatcat tactacctca gttacattga
1021 ggaatgggat ttagtgctgg cagcatctgc ggcttcaaca gaagttagta tccttgctcg
1081 acaaagtgat cagattaatt gggaatcttg gctactggag gattctagtc gagctgaatt
1141 gcctgtgaca gacaagagtg atgactcctt gcccatggga gttgtcgtag actatacaaa
1201 ccaagtggaa atcaccatca gtgatgaaaa gactcttcct cctgctccag ttctcatgtt
1261 actttcaaca gatggtgtgc tttgtccatt ttatatgatt aatcaaaatc ctggggttaa
1321 gtctctcatc aaaacaccag agcgactttc attagaagga gagcgacagc ccaagtcacc
1381 aggaagtact cccactaccc caacctcctc tcaagcccca cagaaactgg atgcttctgc
1441 agctgcagcc cctgcctctc tgccaccttc atcacctgct gctcccattg ccactttttc
1501 tttgcttcct gctggtggag cccccactgt gttctccttt ggttcttcat ctttgaagtc
1561 atcggctacg gtcactgggg agcccccttc atattccagt ggctccgaca gctccaaagc
1621 agccccaggc cctggcccat caaccttctc ttttgttccc ccttctaaag cctccctagc
1681 ccccacccct gcagcgtctc ctgtggctcc atcagctgct tcattctcct ttggatcatc
1741 tggttttaag cctaccctgg aaagcacacc agtgccaagt gtgtctgctc caaatatagc
1801 aatgaagtcc tccttcccac cctcaacctc tgctgtcaaa gtcaacctta gtgaaaagtt
1861 tactgctgca gctacctcta ctcctgttag tagctcccag agcgcacccc cgatgtcgcc
1921 attctcttct gcctccaagc cagctgcttc tggaccactc agccacccca cacctctctc
1981 agcaccacct agttccgtgc cattgaagtc ctcagtcttg ccctcaccat caggacgatc
2041 tgctcagggc agttcaagcc cagtgccctc aatggtacag aaatcaccca ggataacccc
2101 tccagcggca aagccaggct ctccccaggc aaagtcactt cagcctgctg ttgcagaaaa
2161 gcagggacat cagtggaaag attcagatcc tgtaatggct ggaattgggg aggagattgc
2221 acactttcag aaggagttgg aagagttaaa agcccgaact tccaaagcct gtttccaagt
2281 gggcacttct gaggagatga agatgctgcg aacagaatca gatgacttgc atacctttct
2341 tttggagatt aaagagacca cagagtcgct tcatggagat ataagtagcc tgaaaacaac
2401 tttacttgag ggctttgctg gtgttgagga agccagagaa caaaatgaaa gaaatcgtga
2461 ctctggttat ctgcatttgc tttataaaag accactggat cccaagagtg aagctcagct
2521 tcaggaaatt cggcgccttc atcagtatgt gaaatttgct gtccaagatg tgaatgatgt
2581 tctagacttg gagtgggatc agcatctgga acaaaagaaa aaacaaaggc acctgcttgt
2641 gccagagcga gagacactgt ttaacaccct agccaacaat cgggaaatca tcaaccaaca
2701 gaggaagagg ctgaatcacc tggtggatag tcttcagcag ctccgccttt acaaacagac
2761 ttccctgtgg agcctgtcct cggctgttcc ttcccagagc agcattcaca gttttgacag
2821 tgacctggaa agcctgtgca atgctttgtt gaaaaccacc atagaatctc acaccaaatc
2881 cttgcccaaa gtaccagcca aactgtcccc catgaaacag gcacaactga gaaacttctt
2941 ggccaagagg aagaccccac cagtgagatc cactgctcca gccagcctgt ctcgatcagc
3001 ctttctgtct cagagatatt atgaagactt ggatgaagtc agctcaacgt catctgtctc
3061 ccagtctctg gagagtgaag atgcacggac gtcctgtaaa gatgacgagg cagtggttca
3121 ggcccctcgg cacgcccccg tggttcgcac tccttccatc cagcccagtc tcttgcccca
3181 tgcagcacct tttgctaaat ctcacctggt tcatggttct tcacctggtg tgatgggaac
3241 ttcagtggct acatctgcta gcaaaattat tcctcaaggg gccgatagca caatgcttgc
3301 cacgaaaacc gtgaaacatg gtgcacctag tccttcccac cccatctcag ccccgcaggc
3361 agctgccgca gcagcactca ggcggcagat ggccagtcag gcaccagctg taaacacttt
3421 gactgaatca acgttgaaga atgtccctca agtggtaaat gtgcaggaat tgaagaataa
3481 ccctgcaacc ccttctacag ccatgggttc ttcagtgccc tactccacag ccaaaacacc
3541 tcacccagtg ttgaccccag tggctgctaa ccaagccaag caggggtctc taataaattc
3601 ccttaagcca tctgggccta caccagcatc cggtcagtta tcatctggtg acaaagcttc
3661 agggacagcc aagatagaaa cagctgtgac ttcaacccca tctgcttctg ggcagttcag
3721 caagcctttc tcattttctc catcagggac tggctttaat tttgggataa tcacaccaac
3781 accgtcttct aatttcactg ctgcacaagg ggcaacaccc tccactaaag agtcaagcca
3841 gccggacgca ttctcatctg gtgggggaag caaaccttct tatgaggcca ttcctgaaag
3901 ctcacctccc tcaggaatca catccgcatc aaacaccacc ccaggagaac ctgccgcatc
3961 tagcagcaga cctgtggcac cttctggaac tgctctttcc accacctcta gtaagctgga
4021 aaccccaccg tccaagctgg gagagcttct gtttccaagt tctttggctg gagagactct
4081 gggaagtttt tcaggactgc gggttggcca agcagatgat tctacaaaac caaccaataa
4141 ggcttcatcc acaagcctaa ctagtaccca gccaaccaag acgtcaggcg tgccctcagg
4201 gtttaatttt actgcccccc cggtgttagg gaagcacacg gagccccctg tgacatcctc
4261 tgcaaccacc acctcagtag caccaccagc agccaccagc acttcctcaa ctgccgtttt
4321 tggcagtctg ccagtcacca gtgcaggatc ctctggggtc atcagttttg gtgggacatc
4381 tctaagtgct ggcaagacta gtttttcatt tggaagccaa cagaccaata gcacagtgcc
4441 cccatctgcc ccaccaccaa ctacagctgc cactcccctt ccaacatcat tccccacatt
4501 gtcatttggt agcctcctga gttcagcaac taccccctcc ctgcctatgt ccgctggcag
4561 aagcacagaa gaggccactt catcagcttt gcctgagaag ccaggtgaca gtgaggtctc
4621 agcatcagca gcctcacttc tagaggagca acagtcagcc cagcttcccc aggctcctcc
4681 gcaaacttct gactctgtta aaaaagaacc tgttcttgcc cagcctgcag tcagcaactc
4741 tggcactgca gcatctagta ctagtcttgt agcactttct gcagaggcta ccccagccac
4801 cacgggggtc cctgatgcca ggacggaggc agtaccacct gcttcctcct tttctgtgcc
4861 tgggcagact gctgtcacag cagctgctat ctcaagtgca ggccctgtgg ccgtcgaaac
4921 atcaagtacc cccatagcct ccagcaccac gtccattgtt gctcccggcc catctgcaga
4981 ggcagcagca tttggtaccg tcacttctgg ctcatccgtc tttgctcagc ctcctgctgc
5041 cagttctagc tcagctttca accagctcac caacaacaca gccactgccc cctctgccac
5101 gcccgtgttt gggcaagtgg cagccagcac cgcaccaagt ctgtttgggc agcagactgg
5161 tagcacagcc agcacagcag ctgccacacc acaggtcagc agctcagggt ttagcagccc
5221 agcttttggt accacagccc caggggtctt tggacagaca accttcgggc aggcctcagt
5281 ctttgggcag tcggcgagca gtgctgcaag tgtcttttcc ttcagtcagc ctgggttcag
5341 ttccgtgcct gccttcggtc agcctgcttc ctccactccc acatccacca gtggaagtgt
5401 ctttggtgcc gcctcaagta ccagtagctc cagttccttc tcatttggac agtcttctcc
5461 caacacagga ggggggctgt ttggccaaag caacgctcct gcttttgggc agagtcctgg
5521 ctttggacag ggaggctctg tctttggtgg tacctcagct gccaccacaa cagcagcaac
5581 ctctgggttc agcttttgcc aagcttcagg ttttgggtct agtaatactg gttctgtgtt
5641 tggtcaagca gccagtactg gtggaatagt ctttggccag caatcatcct cttccagtgg
5701 taacgtgttt gggtctggaa acactggaag agggggaggt ttcttcagtg gccttggagg
5761 aaaacccagt caggatgcag ccaacaaaaa cccattcagc tcggccagtg ggggctttgg
5821 atccacagct acctcaaata cctctaacct atttggaaac agtggggcca agacatttgg
5881 tggatttgcc agctcgtcgt ttggagagca gaaacccact ggcactttca gctctggagg
5941 aggaagtgtg gcatcccaag gctttgggtt ttcctctcca aacaaaacag gtggcttcgg
6001 tgctgctcca gtgtttggca gccctcctac ttttggggga tcccctgggt ttggaggggt
6061 gccagcattc ggttcagccc cagcctttac aagccctctg ggctcgacgg gaggcaaagt
6121 gttcggagag ggcactgcag ctgccagcgc aggaggattc gggtttggga gcagcagcaa
6181 caccacatcc ttcggcacgc tcgcgagtca gaatgccccc actttcggat cactgtccca
6241 acagacttct ggttttggga cccagagtag cggattctct ggttttggat caggcacagg
6301 agggttcagc tttgggtcaa ataactcgtc tgtccagggt tttggtggct ggcgaagctg
6361 agggcgtgtc agcaggcctt tcgatccctg ggaccaaccg catcctcagc ttcttccccg
6421 agaaatgctg gagcaggctg ttcagaccga cgttgccatc aaaacacata cacccagaaa
6481 gaaacaacag aaaccaaaac tcacaaggcg catgattact tgttttatat ttcatgttgg
6541 gttttccctc ccactattaa acagtctgtt tccgtaaaaa aaaaaaaaaa a
//