LOCUS BC045609 5057 bp mRNA linear HUM 09-JUN-2008
DEFINITION Homo sapiens autophagy/beclin-1 regulator 1, mRNA (cDNA clone
MGC:33725 IMAGE:5296472), complete cds.
ACCESSION BC045609
VERSION BC045609.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5057)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 5057)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (31-JAN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 48 Row: l Column: 19
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 50843826.
FEATURES Location/Qualifiers
source 1..5057
/db_xref="H-InvDB:HIT000052941"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:33725 IMAGE:5296472"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..5057
/gene="AMBRA1"
/gene_synonym="WDR94"
/db_xref="GeneID:55626"
/db_xref="HGNC:HGNC:25990"
/db_xref="MIM:611359"
CDS 361..3987
/gene="AMBRA1"
/gene_synonym="WDR94"
/codon_start=1
/product="autophagy/beclin-1 regulator 1"
/protein_id="AAH45609.1"
/db_xref="GeneID:55626"
/db_xref="HGNC:HGNC:25990"
/db_xref="MIM:611359"
/translation="MKVVPEKNAVRILWGRERGARAMGAQRLLQELVEDKTRWMKWEG
KRVELPDSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVT
FHPTISGLIASGCLDGEVRIWDLHGGSESWFTDSNNAIASLAFHPTAQLLLIATANEI
HFWDWSRREPFAVVKTASEMERVRLVRFDPLGHYLLTAIVNPSNQQGDDEPEIPIDGT
ELSHYRQRALLQSQPVRRTPLLHNFLHMLSSRSSGIQTEPFHPPEQASSTQQDQGLLN
RPSAFSTVQSSTAGNTLRNLSLGPTRRSLGGPLSSHPSRYHREIAPGLTGSEWTRTVL
SLNSRSEAESMPPPRTSASSVSLLSVLRQQEGGSQASVYTSATEGRGFPASGLATESD
GGNGSSQNNSGSIRHELQCDLRRFFLEYDRLQELDQSLSGEAPQTQQAQEMLNNNIES
ERPGPSHQPTPHSSENNSNLSRGHLNRCRACHNLLTFNNDTLRWERTTPNYSSGEASS
SWQVPSSFESVPSSGSQLPPLERTEGQTPSSSRLELSSSASPQEERTVGVAFNQETGH
WERIYTQSSRSGTVSQEALHQDMPEESSEEDSLRRRLLESSLISLSRYDGAGSREHPI
YPDPARLSPAAYYAQRMIQYLSRRDSIRQRSMRYQQNRLRSSTSSSSSDNQGPSVEGT
DLEFEDFEDNGDRSRHRAPRNARMSAPSLGRFVPRRFLLPEYLPYAGIFHERGQPGLA
THSSVNRVLAGAVIGDGQSAVASNIANTTYRLQWWDFTKFDLPEISNASVNVLVQNCK
IYNDASCDISADGQLLAAFIPSSQRGFPDEGILAVYSLAPHNLGEMLYTKRFGPNAIS
VSLSPMGRYVMVGLASRRILLHPSTEHMVAQVFRLQQAHGGETSMRRVFNVLYPMPAD
QRRHVSINSARWLPEPGLGLAYGTNKGDLVICRPEALNSGVEYYWDQLNETVFTVHSN
SRSSERPGTSRATWRTDRDMGLMNAIGLQPRNPATSVTSQGTETLALQLQNAETQTER
EVPEPGTAASGPGEGEGSEYGASGEDALSRIQRLMAEGGMTAVVQREQSTTMASMGGF
GNNIIVSHRIHRSSQTGTEPGAAHTSSPQPSTSRGLLPEAGQLAERGLSPRTASWDQP
GTPGREPTQPTLPSSSPVPIPVSLPSAEGPTVHCELTNNNHLLDGGSSRGDAAGPRGE
PRNR"
BASE COUNT 1202 a 1395 c 1388 g 1072 t
ORIGIN
1 aggggattaa tgaagagcca ccagactatc tttatggaga atctagattg ggaagttaag
61 ctaagaatgt gcatttttga aaaagttttt atggtagaag agaatgtata tcagaggaaa
121 gaatgtagag aagaaagcaa cattgtccac tgggaattga taagttctgc gtagaattta
181 gagttataag gactatctca ttggctccta atgaatgcta aataacaaat ggaaattgct
241 atttccatga ggacaactta caaggacctg tatggcctca ttttagctgc ttcagtgtgt
301 tggagctgtt acttgctcct tcatttcctg ggcctggtgt gacagtggct actgagcgcc
361 atgaaggttg tcccagaaaa gaatgctgtc cggatactct gggggcgaga acggggtgct
421 cgggccatgg gagctcagcg gcttctgcag gagctggtag aggataaaac ccggtggatg
481 aaatgggagg gcaagagagt agaactgccg gatagtccac gctctacctt cttattggcc
541 ttcagcccag acaggactct cttagcctcc acccatgtga accataatat ctatattacg
601 gaggtgaaga ctggcaagtg tgttcattcc ctgattggac accgccgtac tccatggtgt
661 gtcacttttc atcccaccat ctcaggcctt attgcttctg gctgcctaga tggggaggtt
721 aggatttggg atttacacgg tggcagtgaa agctggttca cagatagcaa caatgccatt
781 gcctccctgg ctttccaccc tacggctcag ctcctgctga ttgccactgc caatgagatc
841 cacttctggg actggagtcg acgggaaccc tttgctgtgg tgaagacagc tagtgagatg
901 gaacgggtcc gtctggtgag atttgatcca cttggacact acttactcac agcaattgtt
961 aacccctcta atcaacaggg tgatgacgaa ccagagatcc ccatagatgg aacagaatta
1021 tcccactacc gtcagcgtgc cctcctgcaa tcacagccag ttcgccggac gcctctcctc
1081 cacaatttcc tgcacatgct gtcctcccgc tcttctggca tccagaccga gcccttccat
1141 cccccggagc aggcctcgtc aacgcagcag gaccagggcc tcctgaaccg gccgtctgcc
1201 ttcagtacag tccagagcag cactgccggc aacacgctcc gcaacctcag tctgggtcct
1261 acccgccgct ctttgggagg gcctctgtct agccaccctt ctaggtatca ccgagaaata
1321 gctcctgggt tgacaggatc tgagtggacc cggacagtac tcagtctgaa ctcccgctct
1381 gaggcggaat ccatgccccc gcccagaacc agtgcctctt cggtgagttt gctgtctgtg
1441 ctgagacagc aggaaggtgg ctctcaggca tctgtgtaca cttcagccac agaagggagg
1501 ggttttccgg catcagggtt ggcaactgag tcagatggag ggaatggctc cagccaaaac
1561 aactcgggca gcattcgcca tgagcttcag tgtgacctga gacgcttctt tctggagtat
1621 gaccggcttc aggagctgga tcagagcctg agtggggaag ctccccagac ccaacaggcc
1681 caggaaatgc tcaacaataa cattgaatct gagaggccag gcccttccca ccagcccacc
1741 ccacacagca gtgagaacaa ctccaacctg tcccgtggcc acctgaatcg ctgtcgtgct
1801 tgccacaatc tcctgacctt caacaacgat accctgcgct gggaaagaac cacacctaac
1861 tactcctctg gcgaggctag ttcctcttgg caggtcccca gctcctttga gagtgtgcca
1921 tcaagtggca gccagttgcc acctctcgag cggactgagg gccaaacgcc cagctccagc
1981 aggctggagt tgagcagctc tgctagtccg caggaggaga ggactgtggg ggtggccttt
2041 aaccaggaga caggccactg ggaaagaatt tacacccagt ccagcagatc tggaactgtg
2101 tcacaggagg ccttacatca ggatatgcct gaggagagct ctgaggagga ttcactcagg
2161 aggaggctgc tggaatcttc cctcatttca ttatcccgtt atgatggagc aggatccaga
2221 gagcacccaa tttacccaga cccagcgaga ttatctcctg ctgcatacta cgcccagagg
2281 atgatccagt atctctcacg gagagacagt attcgccagc gctccatgcg ctaccaacag
2341 aaccgtctcc gttcttccac ctcctcctct tcctcagaca accagggtcc atcagtagag
2401 ggaaccgact tggaatttga ggactttgag gacaatggtg acagatccag gcaccgagct
2461 ccacgcaatg cccggatgtc tgcaccttcg cttggacgct ttgtcccaag gcgtttcttg
2521 ctgcctgagt acttgcctta tgctgggatt tttcatgaac gtggacagcc tggcttggct
2581 actcactctt ctgttaacag ggtcctggca ggggcagtga tcggtgatgg acagtctgct
2641 gtggccagta acattgccaa tactacctac cggctccagt ggtgggactt cactaagttt
2701 gacctccctg aaatcagtaa tgcttccgtg aatgtgctgg tgcagaactg caagatctac
2761 aatgatgcca gctgtgacat ttctgcagat ggccagctcc tggcagcttt catccccagc
2821 agccagaggg gctttcctga tgaaggcatc ctggcagtgt actccctggc cccccataac
2881 ctgggcgaaa tgctctacac caagcgattt ggtcccaatg ccatttcggt gagcctgtcc
2941 ccaatgggca gatatgtaat ggtgggcttg gcctcacgaa ggatcctgct gcacccctcc
3001 acagagcaca tggtggccca ggtcttcagg ctgcaacagg cccatggtgg agagacctcc
3061 atgaggagag ttttcaacgt cctttatccc atgcctgccg accagcggag acatgtcagt
3121 atcaactctg cccgttggct gcctgagcca gggcttggct tggcctatgg tactaacaaa
3181 ggagacctgg tgatctgccg accagaggcc ttaaactctg gtgttgagta ctactgggac
3241 cagctgaacg agacggtctt cactgtccat tccaacagca ggagcagcga gcggcctgga
3301 accagcagag ccacatggag gacagacaga gacatggggc tgatgaatgc cattgggctt
3361 cagccccgga accctgccac ctcagtgaca tctcagggca ccgagactct ggcccttcag
3421 ctgcagaatg ccgaaacaca gactgagagg gaggtgccgg agccagggac agccgcctca
3481 ggtcctggtg aaggtgaggg ttcagagtat ggtgccagtg gagaagatgc gctcagcagg
3541 atccagaggc tgatggcgga gggcggcatg acagccgtgg tgcagcggga gcagagcacc
3601 accatggcct ccatgggcgg cttcggcaac aacatcatcg tcagccaccg cattcaccgc
3661 agctctcaga cgggcactga acctggtgcc gcccacacct cctcacccca gccctccacc
3721 tctcggggac tgctcccaga ggccgggcaa ctggcagagc gaggcctaag cccccggaca
3781 gcttcctggg accagcctgg tacccctggg cgggagccaa cccagccaac cctgccctct
3841 tcctcccctg tccccattcc tgtttccctt cccagcgctg agggaccaac cgtccactgc
3901 gagttgacca ataacaacca ccttctggat ggtggcagca gcagggggga cgctgcaggc
3961 cctaggggag aaccacggaa caggtagaga caaacgttgc actggtgcct cccctcgaac
4021 cgccaagcag aaaccggacc tcacagctga ctgggaactg gacatgtgga agagctgctg
4081 gctgcatcag ggaacaggag gaggaagagg gtcagggtgg agaggaagat cagtcagtgg
4141 gcacaagaca gtcaaatggg caaggcctgc ctcggggaac tagaaccttc caggatctgg
4201 agcccgggag agccacactg tgggcttaat gtgaatagag gaacaagtgg gtatctctgc
4261 caggcacccc actttctcct agtaacatgg gctcagggga ctcagccctg gacagagtgc
4321 ctccagagag tgaacagtct tccagatctg ggccaatcat cctggacaga ggcccgcgag
4381 gcagctttgc cctgtccacc tgttgggtgg gcagagccac caggaaccca gacaccacct
4441 ccaactctga gccttccaga gcttcagcct ctcttcgtcg tcttacccca ctgaaaccaa
4501 cagggatcgg gccaggctcc cagattcttg aggacaggga cttcggcatt tactaatggg
4561 ggactactgt ggggtaaggg ggcgcctgct tgcctgatac aggatggggt caagggacag
4621 tgggcaggtc ctcactcagg agtggggggt gtaggctggc cagcccccag ggcttgtcca
4681 ccagtcttct ccccgcaagg ccctcagagc agcgcctgtg ggtgtcagta ttacctgagc
4741 ctaggccaaa gctagcccaa ggctggggaa ggggaggaga ctccaggtca gaatgtgagg
4801 tctcagtctg tgatttaagg tgttgcatgt ggactcttaa ctgtacgtgt agtttctagt
4861 ggagaaatca aggctctgat cattttgttt ttagtatgaa aatgtgattt cctttctgtt
4921 tgtaactcat catagaaaca ttgtggtggg aggagagggg atagtctaca gctaatgagg
4981 gaaacaccaa agatcacatc attaaaatga tgacatgccc ctcaaaaaaa aaaaaaaaaa
5041 gaaaaaaaaa aaaaaaa
//