LOCUS BC043494 3306 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens WD repeat domain 5B, mRNA (cDNA clone MGC:49879
IMAGE:6056052), complete cds.
ACCESSION BC043494
VERSION BC043494.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3306)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3306)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (09-JAN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 89 Row: n Column: 20
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 42544246.
FEATURES Location/Qualifiers
source 1..3306
/db_xref="H-InvDB:HIT000052821"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:49879 IMAGE:6056052"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_72"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3306
/gene="WDR5B"
/gene_synonym="FLJ11287"
/gene_synonym="MGC49879"
/db_xref="GeneID:54554"
/db_xref="HGNC:HGNC:17826"
CDS 97..1089
/gene="WDR5B"
/gene_synonym="FLJ11287"
/gene_synonym="MGC49879"
/codon_start=1
/product="WD repeat domain 5B"
/protein_id="AAH43494.1"
/db_xref="GeneID:54554"
/db_xref="HGNC:HGNC:17826"
/translation="MATKESRDAKAQLALSSSANQSKEVPENPNYALKCTLVGHTEAV
SSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSAS
DDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCL
KTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKF
SPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSED
NLVYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIASAALENDKTIKLWMSNH"
BASE COUNT 927 a 625 c 680 g 1074 t
ORIGIN
1 tttatcttca ttttgctggg cagaaagcca aagtactgga ctgcctggtt cagggctgaa
61 cgcctagtac acctgctaac ttggagcttc agagccatgg caaccaagga gtcaagagac
121 gccaaagcac agttggccct ctcctcatcg gccaatcaga gcaaggaagt gcctgaaaac
181 ccaaactatg ctctcaaatg tactcttgtg ggacacacgg aagcagtgtc atcagttaag
241 tttagtccta atggagaatg gctagcaagt tcttctgctg ataggctaat cataatttgg
301 ggagcatatg atggaaaata tgagaaaaca ctctatggtc ataatttgga aatatcggat
361 gttgcctggt catcagattc cagtcgtctt gtttctgcct cagatgataa aactctaaaa
421 ttatgggatg tgagatctgg aaaatgtttg aaaacactga aggggcacag taattatgtc
481 ttttgttgta acttcaatcc gccatccaac cttataatct cgggatcttt tgatgagact
541 gtaaaaatat gggaggtgaa aacaggaaag tgtctcaaga ctttgtctgc tcattctgac
601 ccagtttctg ctgttcattt taattgtagt gggtccttga tagtgtcagg tagctatgat
661 ggcctctgta gaatctggga tgctgcatca ggtcagtgtt taaaaacgct cgttgatgac
721 gataaccctc ctgtctcttt tgtaaaattt tctccaaatg gtaaatacat tctcactgca
781 actttggaca acactcttaa actatgggat tatagcagag gcaggtgcct gaaaacatac
841 actggtcata agaatgagaa atattgcata tttgccaatt tttcagttac tggtggaaag
901 tggattgtgt ctggttccga ggataacctg gtttacattt ggaaccttca gactaaagag
961 attgtgcaga aattacaagg ccatacagat gttgtgatct cagcagcttg tcatcctaca
1021 gaaaacctca tcgcatcagc agcattagaa aatgacaaaa caattaaact gtggatgagt
1081 aaccactaat ccctttgaaa atcaagtagt agagccaagt tggccaaaaa acttggatat
1141 ttaaaaagac ggtttctttt aattttggca gtttggtatt ttaaaaattg tctattgtta
1201 aattttgaga ttcatacact acatttacaa aatgagatag ttgaaaaagc acatctagaa
1261 ttcagcttct gactaccaat cttttttgag caactttttg taatttttat ggatttatgt
1321 cacttttatt acagggatat attgcatagt ggtgaaatct gggcttagta taccctcacc
1381 caaatagtat acattgtacc tagtaaatac tttcccatct ctcaccccac tcccaccttt
1441 gaaggctcta gtgtctatga ttctgctctc cacgtccagg tgtacacatt gtttatctcc
1501 cacttatgag aacatgtggt ttttgacttt ctgtatcatt acttcactta atggcctcca
1561 ggtccatcca tgttgttgca aaagataaga tttcattatt tttttttggc tgagtagtat
1621 tctgtggtgt gtatgtgtgt gtgtgtatgc atatatgtgt atgtgtatgt atataagtat
1681 atacaccaca ttatccagtc atctggatat gtatataagt atatacacca cattttcttt
1741 atccagtcat ctcttgatgg acccttaggt tggttccata actttgctat tacgaatagt
1801 gctgcgataa acagcactat tatgaatagt gctgcgataa acagtgcagg tgattttaaa
1861 atataatttc ctttgggtag atacctacta gtgggattgc tggatcgaat ggtagttttt
1921 agttggaaaa tctccatact gttttccaga ggttgtaaaa tgtacattcc tccccacagt
1981 gtataagctg tgcctttact ctgcatcttt gccatgattc tttttgagac agagtctctg
2041 gtgcccaggc tggagtgcag tggcacaatc ttggctcact gcaacctctg cctcccgggt
2101 tcaagcagtt ctcatgtctc aacatcccag gtagctagga ttacaggcgt gccaccatgc
2161 ctggctaatg tttctatttt tagtagagac agggtttcac catgttcgag gctggtcttg
2221 aactcctggc ctcaagtgat ccacctgcct cggcctccca aagtgctggg attacaggca
2281 tgagccactg tacccagcca ttttttgact ttttaataat agccattcta actggtttaa
2341 gagagtatct cattgtggtt atattttgta ttcctctgat gattagtgat gttgagcatt
2401 tttttgtgtg tgtttgttgg ccacttgtat gtcttctttg aaaactgact tctaatcttg
2461 aggcctatta ataatttcat ttgtctgtca ctggacaatt tctcattcct ctcagtgact
2521 atcctagagg atcagtgtat ttgagaaata tttagaagta aagttgacag gacaggatga
2581 ttgattaaaa gaggggagca agggaatttg aaataattcc agggtttctg gtttgggaga
2641 tcagatgaac aagtgcataa gcctgggatg ctggtggagg actggagaga catgccagat
2701 gctacctgca cacttttggt aatattctgt gtgatgggat atgaaatggt ccatagaaaa
2761 aaaccggaaa aatacgccaa ggttaggttc attctaagag tctaaaaatt tcaaaaacca
2821 aaacaacatt ataaatggtg tttctcaagg acctttcact acctttttag attgtgcttg
2881 tgattttcag gcaagctaaa tgtctgatga agactgctct tcttttgttc tgtgtctgac
2941 ctactaattc ctgcccatgc ttcaaactca gttcagaaat cactgaagga accatccact
3001 gccggcctgc ctgcaaccac agctgacagc tgagttagtt aggttttcct gtccctatta
3061 tttaccagtt tgtactgaaa tgctttcatg ggctgtgctt ccagattatg agttctgtgg
3121 aatcaggaag tatgtctctg tattcttgta ttctttggct tttttgtgta gtaaagggac
3181 tcaagtaatg tttgacagtg aaggatacaa cttcattcct tgcctgcttt gataaatttt
3241 agtaataaat tcccaaaact atcatgttga ttaaaaataa aaagtaaccg taaaaaaaaa
3301 aaaaaa
//