LOCUS BC043487 3575 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens calcium/calmodulin-dependent protein kinase kinase 1,
alpha, mRNA (cDNA clone MGC:49844 IMAGE:5751570), complete cds.
ACCESSION BC043487
VERSION BC043487.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3575)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3575)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (09-JAN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 89 Row: h Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 27437009.
FEATURES Location/Qualifiers
source 1..3575
/db_xref="H-InvDB:HIT000052817"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:49844 IMAGE:5751570"
/tissue_type="Brain, Lung, Testis, adult, pooled whole"
/clone_lib="NIH_MGC_115"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3575
/gene="CAMKK1"
/gene_synonym="CAMKKA"
/gene_synonym="DKFZp761M0423"
/gene_synonym="MGC34095"
/db_xref="GeneID:84254"
/db_xref="HGNC:HGNC:1469"
CDS 125..1642
/gene="CAMKK1"
/gene_synonym="CAMKKA"
/gene_synonym="DKFZp761M0423"
/gene_synonym="MGC34095"
/codon_start=1
/product="calcium/calmodulin-dependent protein kinase
kinase 1, alpha"
/protein_id="AAH43487.1"
/db_xref="GeneID:84254"
/db_xref="HGNC:HGNC:1469"
/translation="MEGGPAVCCQDPRAELVERVAAIDVTHLEEADGGPEPTRNGVDP
PPRARAASVIPGSTSRLLPARPSLSARKLSLQERPAGSYLEAQAGPYATGPASHISPR
AWRRPTIESHHVAISDAEDCVQLNQYKLQSEIGKGAYGVVRLAYNESEDRHYAMKVLS
KKKLLKQYGFPRRPPPRGSQAAQGGPAKQLLPLERVYQEIAILKKLDHVNVVKLIEVL
DDPAEDNLYLVFDLLRKGPVMEVPCDKPFSEEQARLYLRDVILGLEYLHCQKIVHRDI
KPSNLLLGDDGHVKIADFGVSNQFEGNDAQLSSTAGTPAFMAPEAISDSGQSFSGKAL
DVWATGVTLYCFVYGKCPFIDDFILALHRKIKNEPVVFPEEPEISEELKDLILKMLDK
NPETRIGVPDIKLHPWVTKNGEEPLPSEEEHCSVVEVTEEEVKNSVRLIPSWTTVILV
KSMLRKRSFGNPFEPQARREERSMSAPGNLLVKEGFGEGGKSPELPGVQEDEAAS"
BASE COUNT 798 a 994 c 1080 g 703 t
ORIGIN
1 cggggcgggg cggggcgggg cgcgcagcag gagcgagtgg ggccgcccgc cgggccacgg
61 acactgtcgc ccggcgccca ggttcccaac aaggctacgc agaagaaccc ccttgactga
121 agcaatggag gggggtccag ctgtctgctg ccaggatcct cgggcagagc tggtagaacg
181 ggtggcagcc atcgatgtga ctcacttgga ggaggcagat ggtggcccag agcctactag
241 aaacggtgtg gaccccccac cacgggccag agctgcctct gtgatccctg gcagtacttc
301 aagactgctc ccagcccggc ctagcctctc agccaggaag ctttccctac aggagcggcc
361 agcaggaagc tatctggagg cgcaggctgg gccttatgcc acggggcctg ccagccacat
421 ctccccccgg gcctggcgga ggcccaccat cgagtcccac cacgtggcca tctcagatgc
481 agaggactgc gtgcagctga accagtacaa gctgcagagt gagattggca agggtgccta
541 cggtgtggtg aggctggcct acaacgaaag tgaagacaga cactatgcaa tgaaagtcct
601 ttccaaaaag aagttactga agcagtatgg ctttccacgt cgccctcccc cgagagggtc
661 ccaggctgcc cagggaggac cagccaagca gctgctgccc ctggagcggg tgtaccagga
721 gattgccatc ctgaagaagc tggaccacgt gaatgtggtc aaactgatcg aggtcctgga
781 tgacccagct gaggacaacc tctatttggt gtttgacctc ctgagaaagg ggcccgtcat
841 ggaagtgccc tgtgacaagc ccttctcgga ggagcaagct cgcctctacc tgcgggacgt
901 catcctgggc ctcgagtact tgcactgcca gaagatcgtc cacagggaca tcaagccatc
961 caacctgctc ctgggggatg atgggcacgt gaagatcgcc gactttggcg tcagcaacca
1021 gtttgagggg aacgacgctc agctgtccag cacggcggga accccagcat tcatggcccc
1081 cgaggccatt tctgattccg gccagagctt cagtgggaag gccttggatg tatgggccac
1141 tggcgtcacg ttgtactgct ttgtctatgg gaagtgccca ttcatcgacg atttcatcct
1201 ggccctccac aggaagatca agaatgagcc cgtggtgttt cctgaggagc cagaaatcag
1261 cgaggagctc aaggacctga tcctgaagat gttagacaag aatcccgaga cgagaattgg
1321 ggtgccagac atcaagttgc acccttgggt gaccaagaac ggggaggagc cccttccttc
1381 ggaggaggag cactgcagcg tggtggaggt gacagaggag gaggttaaga actcagtcag
1441 gctcatcccc agctggacca cggtgatcct ggtgaagtcc atgctgagga agcgttcctt
1501 tgggaacccg tttgagcccc aagcacggag ggaagagcga tccatgtctg ctccaggaaa
1561 cctactggtg aaagaagggt ttggtgaagg gggcaagagc ccagagctcc ccggcgtcca
1621 ggaagacgag gctgcatcct gagcccctgc atgcacccag ggccacccgg cagcacactc
1681 atcccgcgcc tccagaggcc cacccctcat gcaacagccg cccccgcagg cagggggctg
1741 gggactgcag ccccactccc gcccctcccc catcgtgctg catgacctcc acgcacgcac
1801 gtccagggac agactggaat gtatgtcatt tggggtcttg ggggcagggc tcccacgagg
1861 ccatcctcct cttcttggcc ctccttggcc tgacccattc tgtggggaaa ccgggtgccc
1921 atggagcctc agaaatgcca cccggctggt tggcatggcc tggggcagga ggcagaggca
1981 ggagaccaag atggcaggtg gaggccaggc ttaccacaac ggaagagacc tcccgctggg
2041 gccgggcagg cctggctcag ctgccacagg catatggtgg agaggggggt accctgccca
2101 ccttggggtg gtggcaccag agctcttgtc tattcagacg ctggtatggg ggctcggacc
2161 cctcactggg gacagggcca gtgttggaga attctgattc ctttttttgt tgtcttttac
2221 ttttgttttt aacctggggg ttcggggaga ggccctgctt gggaacatct cacgagcttt
2281 cctacatctt ccgtggttcc cagcacagcc caagattatt tggcagccaa gtggatggaa
2341 ctaactttcc tggactgtgt ttcgcattcg gcgttatctg gaaagtggac tgaacggaat
2401 caagctctga gcagaggcct gaagcggaag caccacatcg tccctgccca tctcactctc
2461 tcccttgatg atgcccctag agctgaggct ggagaagaca ccagggctga ctttgactga
2521 gggccatgga cgcgacaggc ctgtggccct gcgcatgctg aaataactgg aacccagcct
2581 ctcctcctac accggcctac ccatctgggc ccaagagctg cactcacact cctacaacga
2641 aggacaaact gtccaggtcg gagggatcac gagacacaga acctggaggg gtgtgcacgc
2701 tggcaggtgg cctctgcggc aattgcctca ccctgaggac atcagcagtc agcctgctca
2761 gagcgggggt gctggagcgc gtgcagacac agctcttccg gagcagcctt caccttctct
2821 ctgggatcag tgtccggctg gccgacgtgg catttgctga ccgaatgctc atagaggttg
2881 acccccacag ggtcacgcag gactcggaca ctgccctgga aacatggatg gacaagggct
2941 tttggccaca ggtgtgggtg tcctgttgga ggagggcttg tttggagaag ggaggctggc
3001 tgggggagaa acccggatcc cgctgcatct ccgcgcctgt gggtgcatgt cgcgtgctca
3061 tctgttgcac acagctcact cgtatgtcct gcactggtac atgcatctgt aatacagttt
3121 ctacgtctat ttaaggctag gagccgaatg tgccccattg tcagtgggtc cacgtttctc
3181 cccggctcct ctgggctaag gcagtgtggc ccgaggctta aaaagttact cggtactgtt
3241 tttaagaaca cttttataga gttagtggaa ggcaagttaa gagccaatca ctgatcccca
3301 agtgtttctt gagcatctgg tctgggggga ccactttgat cggacccacc cttggaaagc
3361 tcaggggtag gcccaggtgg gatgctcacc ctgtcactga gggttttggt tggcatcgtt
3421 gtttttgaat gtagcacaag cgatgagcaa actctataag agtgttttaa aaattaactt
3481 cccaggaagt gagttaaaaa caataaaagc ccttttttgg gtttaaaagg aaaaaaaaaa
3541 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa
//