LOCUS BC042899 3028 bp mRNA linear HUM 11-APR-2007
DEFINITION Homo sapiens sphingomyelin synthase 1, mRNA (cDNA clone MGC:17342
IMAGE:4342258), complete cds.
ACCESSION BC042899
VERSION BC042899.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3028)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3028)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (06-JAN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Lou Staudt
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 26 Row: k Column: 3
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 41350331.
FEATURES Location/Qualifiers
source 1..3028
/db_xref="H-InvDB:HIT000052754"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:17342 IMAGE:4342258"
/tissue_type="Lymph, lymphoma"
/clone_lib="NIH_MGC_85"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3028
/gene="SGMS1"
/gene_synonym="MOB"
/gene_synonym="MOB1"
/gene_synonym="SMS1"
/db_xref="GeneID:259230"
/db_xref="HGNC:HGNC:29799"
CDS 216..1457
/gene="SGMS1"
/gene_synonym="MOB"
/gene_synonym="MOB1"
/gene_synonym="SMS1"
/codon_start=1
/product="sphingomyelin synthase 1"
/protein_id="AAH42899.1"
/db_xref="GeneID:259230"
/db_xref="HGNC:HGNC:29799"
/translation="MKEVVYWSPKKVADWLLENAMPEYCEPLEHFTGQDLINLTQEDF
KKPPLCRVSSDNGQRLLDMIETLKMEHHLEAHKNGHANGHLNIGVDIPTPDGSFSIKI
KPNGMPNGYRKEMIKIPMPELERSQYPMEWGKTFLAFLYALSCFVLTTVMISVVHERV
PPKEVQPPLPDTFFDHFNRVQWAFSICEINGMILVGLWLIQWLLLKYKSIISRRFFCI
VGTLYLYRCITMYVTTLPVPGMHFNCSPKLFGDWEAQLRRIMKLIAGGGLSITGSHNM
CGDYLYSGHTVMLTLTYLFIKEYSPRRLWWYHWICWLLSVVGIFCILLAHDHYTVDVV
VAYYITTRLFWWYHTMANQQVLKEASQMNLLARVWWYRPFQYFEKNVQGIVPRSYHWP
FPWPVVHLSRQVKYSRLVNDT"
BASE COUNT 914 a 596 c 605 g 913 t
ORIGIN
1 caaaaatgag gtgaattaat acttgggcgc tcaggaaccc tggacagcta catgaggtgt
61 ttaaaaactg ccctgaccat cttgccaaac aagtctctgc tcatgaggcc ccacaggatg
121 aacgagccga ggcaggacag tgtcctgccc tgtcggaaca gtgactgctg acctgccaag
181 agagagctgg ggactgcctg ctgtctgcca gtacaatgaa ggaagtggtt tattggtcac
241 ccaagaaggt ggcagactgg ctgctggaga atgctatgcc agaatactgt gagcctctgg
301 agcatttcac aggccaggac ttgatcaacc taacccaaga ggatttcaaa aaacccccct
361 tgtgccgagt ctcctctgac aacgggcagc ggctcctgga catgatagaa accctgaaaa
421 tggagcacca tttggaagca cacaagaacg gccatgccaa tgggcacctc aacattggcg
481 tagacatccc cacccccgac ggcagcttca gcatcaagat taaacccaac gggatgccaa
541 atgggtatag gaaagagatg ataaagatcc ccatgccaga actggagcgc tctcagtacc
601 ccatggagtg gggcaagact tttctggcct ttctttatgc actttcctgt ttcgttctca
661 ccacagtgat gatctcggtc gtccacgaac gagtacctcc taaggaggtg cagcctccac
721 taccggacac attttttgac cattttaacc gggtgcagtg ggccttttct atttgtgaaa
781 ttaatggcat gatccttgta ggactctggt taattcagtg gctgctctta aaatacaagt
841 ctattattag cagaagattt ttctgcatag ttggcacgct gtacctgtat cggtgtatta
901 caatgtatgt aactacactc ccagtacctg gtatgcattt caactgttct ccgaagcttt
961 tcggagactg ggaagcccaa ctgcgaagaa taatgaagct cattgctgga ggtggcttgt
1021 ctatcactgg ctctcacaac atgtgtgggg actatctgta cagcggccac acggtcatgc
1081 taacacttac ctacttattt atcaaagagt attcccctcg gcgactctgg tggtatcact
1141 ggatttgctg gcttctcagc gtagttggaa tcttctgtat tctcttagcg catgaccact
1201 acactgtgga cgtggtggtg gcatattaca tcaccacgag actcttctgg tggtatcaca
1261 ctatggccaa tcagcaagtg ctaaaggaag cttcccagat gaacctcctg gccagggtgt
1321 ggtggtacag gccatttcag tactttgaaa agaatgtcca aggaattgta cctcgatctt
1381 accattggcc tttcccctgg ccagtagtcc acctcagtag gcaagttaaa tacagccggc
1441 tggtgaatga cacataacag ctgtacaaag tggggaaaag acaaattgtc cgaagtgcta
1501 agaactccat gagagaagat gccataaaat aaacacctcc ctaatcctat tatctttcaa
1561 tggttacctt gacttaacct attgagttac ctggtcagca ctgtgatctt tttttctctc
1621 caaaggacct gcgttggaca acaataaaga aaaatttaac ctatcatgca ctgtacacat
1681 ttcctgttca taagtttggg atttacataa cccgcaacca ccatgttcct ttgtatatga
1741 tgcagcagca taaatgtaag cttttatatc ataagttctg gtctttccag tcacatctgg
1801 aaataaagcg tattattttc ttgggaaaac atacttttca tatctcttgc cccaaagatt
1861 gggctgtaag ccattttcta gcaaatgtct ctatgaaggt ttctaagtac ctgaatgggg
1921 tttgattctg aaatctttct acctgttgca ccgatattca aataaaaatg atagacacag
1981 aaaggtttgg taactttggg ttttgtaaaa tcagcaaagg cagtgtttca aaaagtgcaa
2041 aaaaaaagat tctgttataa agtgattttc taagtatttc ctaactttat ttttcaaaat
2101 gatgttatga acaccaaatt taaagatttt taacatgtca gagagaagag agttaaaatt
2161 taaaaatgca tcttgggaga gaaatttgtc tatgtttcta gtgcctttct tgtcttgatt
2221 gtatggtcag taggcaatct taaatgtttt tatttaaaat aaagtattcc ttgaaaatat
2281 aaatatatgt atacactact aaattttgca tttatagcta aattgaatca gaagactgct
2341 tatggtttta aaattgcaat gacttaaata atgaggttgt taattagagt cagagcctgt
2401 tcacatattg tgatcaggta gcaatgacat gtaccactta aattatttta tcgtcgattt
2461 ggtagttcga ttttaactac tcaatgaaaa cagccatgaa tatcttttct taaagagagt
2521 tttgaaaatg atcacttacc taaaacttga aagctatgaa ttagttatcc atactctcat
2581 gacaattttg ttggtgaaca acaaaaaaga gatctatttc tttaaaagat atttgtgcag
2641 aaactgcatg taactctaag ttttactcct aacatacata tgtttgggga agtattctat
2701 tctatacttg cctatgtgga gaacaaaata gttttttaag aatgaagaag tatatatatc
2761 cattctgtat tttacgtgca gcagaattat cttccgtagg atttttttgt gtattcacaa
2821 ggtgatattt gtattgtaaa acaataatgg tgaaggaaat aaaaaggctt ttaaaatttt
2881 gtttgtttta aatctttgta aagttattat tccagagagt atactggtat cttacagctt
2941 acctagatca taaattaatc aaaatgcact ttttaataaa aactgatact taaaataaat
3001 ggctgttatt tctaaaaaaa aaaaaaaa
//