LOCUS BC042637 1762 bp mRNA linear HUM 03-NOV-2006
DEFINITION Homo sapiens activin A receptor type II-like 1, mRNA (cDNA clone
MGC:34522 IMAGE:5179243), complete cds.
ACCESSION BC042637
VERSION BC042637.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1762)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1762)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-JAN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 51 Row: p Column: 13
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4557242.
FEATURES Location/Qualifiers
source 1..1762
/db_xref="H-InvDB:HIT000052732"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:34522 IMAGE:5179243"
/tissue_type="Brain, Lung, Testis, adult, pooled whole"
/clone_lib="NIH_MGC_115"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1762
/gene="ACVRL1"
/gene_synonym="ALK-1"
/gene_synonym="ALK1"
/gene_synonym="HHT"
/gene_synonym="HHT2"
/gene_synonym="SKR3"
/gene_synonym="TSR-I"
/db_xref="GeneID:94"
/db_xref="HGNC:HGNC:175"
/db_xref="MIM:601284"
CDS 33..1544
/gene="ACVRL1"
/gene_synonym="ALK-1"
/gene_synonym="ALK1"
/gene_synonym="HHT"
/gene_synonym="HHT2"
/gene_synonym="SKR3"
/gene_synonym="TSR-I"
/codon_start=1
/product="activin A receptor type II-like 1"
/protein_id="AAH42637.1"
/db_xref="GeneID:94"
/db_xref="HGNC:HGNC:175"
/db_xref="MIM:601284"
/translation="MTLGSPRKGLLMLLMALVTQGDPVKPSRGPLVTCTCESPHCKGP
TCRGAWCTVVLVREEGRHPQEHRGCGNLHRELCRGRPTEFVNHYCCDSHLCNHNVSLV
LEATQPPSEQPGTDGQLALILGPVLALLALVALGVLGLWHVRRRQEKQRGLHSELGES
SLILKASEQGDSMLGDLLDSDCTTGSGSGLPFLVQRTVARQVALVECVGKGRYGEVWR
GLWHGESVAVKIFSSRDEQSWFRETEIYNTVLLRHDNILGFIASDMTSRNSSTQLWLI
THYHEHGSLYDFLQRQTLEPHLALRLAVSAACGLAHLHVEIFGTQGKPAIAHRDFKSR
NVLVKSNLQCCIADLGLAVMHSQGSDYLDIGNNPRVGTKRYMAPEVLDEQIRTDCFES
YKWTDIWAFGLVLWEIARRTIVNGIVEDYRPPFYDVVPNDPSFEDMKKVVCVDQQTPT
IPNRLAADPVLSGLAQMMRECWYPNPSARLTALRIKKTLQKISNSPEKPKVIQ"
BASE COUNT 380 a 508 c 552 g 322 t
ORIGIN
1 ctccacctct cttgctcctc tctgcaggga ccatgacctt gggctccccc aggaaaggcc
61 ttctgatgct gctgatggcc ttggtgaccc agggagaccc tgtgaagccg tctcggggcc
121 cgctggtgac ctgcacgtgt gagagcccac attgcaaggg gcctacctgc cggggggcct
181 ggtgcacagt agtgctggtg cgggaggagg ggaggcaccc ccaggaacat cggggctgcg
241 ggaacttgca cagggagctc tgcagggggc gccccaccga gttcgtcaac cactactgct
301 gcgacagcca cctctgcaac cacaacgtgt ccctggtgct ggaggccacc caacctcctt
361 cggagcagcc gggaacagat ggccagctgg ccctgatcct gggccccgtg ctggccttgc
421 tggccctggt ggccctgggt gtcctgggcc tgtggcatgt ccgacggagg caggagaagc
481 agcgtggcct gcacagcgag ctgggagagt ccagtctcat cctgaaagca tctgagcagg
541 gcgacagcat gttgggggac ctcctggaca gtgactgcac cacagggagt ggctcagggc
601 tccccttcct ggtgcagagg acagtggcac ggcaggttgc cttggtggag tgtgtgggaa
661 aaggccgcta tggcgaagtg tggcggggct tgtggcacgg tgagagtgtg gccgtcaaga
721 tcttctcctc gagggatgaa cagtcctggt tccgggagac tgagatctat aacacagtgt
781 tgctcagaca cgacaacatc ctaggcttca tcgcctcaga catgacctcc cgcaactcga
841 gcacgcagct gtggctcatc acgcactacc acgagcacgg ctccctctac gactttctgc
901 agagacagac gctggagccc catctggctc tgaggctagc tgtgtccgcg gcatgcggcc
961 tggcgcacct gcacgtggag atcttcggta cacagggcaa accagccatt gcccaccgcg
1021 acttcaagag ccgcaatgtg ctggtcaaga gcaacctgca gtgttgcatc gccgacctgg
1081 gcctggctgt gatgcactca cagggcagcg attacctgga catcggcaac aacccgagag
1141 tgggcaccaa gcggtacatg gcacccgagg tgctggacga gcagatccgc acggactgct
1201 ttgagtccta caagtggact gacatctggg cctttggcct ggtgctgtgg gagattgccc
1261 gccggaccat cgtgaatggc atcgtggagg actatagacc acccttctat gatgtggtgc
1321 ccaatgaccc cagctttgag gacatgaaga aggtggtgtg tgtggatcag cagaccccca
1381 ccatccctaa ccggctggct gcagacccgg tcctctcagg cctagctcag atgatgcggg
1441 agtgctggta cccaaacccc tctgcccgac tcaccgcgct gcggatcaag aagacactac
1501 aaaaaattag caacagtcca gagaagccta aagtgattca atagcccagg agcacctgat
1561 tcctttctgc ctgcaggggg ctgggggggt ggggggcagt ggatggtgcc ctatctgggt
1621 agaggtagtg tgagtgtggt gtgtgctggg gatgggcagc tgcgcctgcc tgtttggccc
1681 ccagcccccc cagccaaaaa tacagctggg ctgaaacctg aaaaaaaaaa aaaaaaaaaa
1741 aaaaaaaaaa aaaaaaaaaa aa
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