LOCUS BC042605 3888 bp mRNA linear HUM 07-OCT-2003
DEFINITION Homo sapiens FK506 binding protein 5, mRNA (cDNA clone MGC:34489
IMAGE:4539929), complete cds.
ACCESSION BC042605
VERSION BC042605.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3888)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3888)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (02-JAN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 52 Row: c Column: 24
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 17149847.
FEATURES Location/Qualifiers
source 1..3888
/db_xref="H-InvDB:HIT000052721"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:34489 IMAGE:4539929"
/tissue_type="Testis, embryonal carcinoma"
/clone_lib="NIH_MGC_92"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3888
/gene="FKBP5"
/gene_synonym="FKBP51"
/gene_synonym="FKBP54"
/gene_synonym="P54"
/gene_synonym="PPIase"
/gene_synonym="Ptg-10"
/db_xref="GeneID:2289"
/db_xref="MIM:602623"
CDS 317..1690
/gene="FKBP5"
/gene_synonym="FKBP51"
/gene_synonym="FKBP54"
/gene_synonym="P54"
/gene_synonym="PPIase"
/gene_synonym="Ptg-10"
/codon_start=1
/product="FKBP5 protein"
/protein_id="AAH42605.1"
/db_xref="GeneID:2289"
/db_xref="MIM:602623"
/translation="MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGE
ETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEI
CHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYS
NPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILY
LGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGT
VYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYT
KAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQIS
MCQKKAKEHNERDRRIYANMFKKFAEQDAKEEANKAMGKKTSEGVTNEKGTDSQAMEE
EKPEGHV"
misc_feature 437..721
/gene="FKBP5"
/gene_synonym="FKBP51"
/gene_synonym="FKBP54"
/gene_synonym="P54"
/gene_synonym="PPIase"
/gene_synonym="Ptg-10"
/note="FKBP; Region: FKBP-type peptidyl-prolyl cis-trans
isomerase"
/db_xref="CDD:pfam00254"
misc_feature 782..1060
/gene="FKBP5"
/gene_synonym="FKBP51"
/gene_synonym="FKBP54"
/gene_synonym="P54"
/gene_synonym="PPIase"
/gene_synonym="Ptg-10"
/note="FKBP; Region: FKBP-type peptidyl-prolyl cis-trans
isomerase"
/db_xref="CDD:pfam00254"
BASE COUNT 1166 a 805 c 895 g 1022 t
ORIGIN
1 agaacaaact cctacctctg tttgcaacta agagttacat cccccatgcc aagaccttcc
61 gaggcgtccc agagggggaa attcctcgct gccggactgc gcccaccctt gaggacctca
121 cattctcttt gggcagagcg gaagccagac agagacaggg actacgaagc gacaatcccc
181 agccctgtgt gtgcaaggag cccccgaggg gcaggcagcc acgctgcaga aggctagact
241 ctccgacccc cagggagcct ggtgtgggct gcagggacag aacgcttctc agaggaggtt
301 ctctacttaa aagacaatga ctactgatga aggtgccaag aacaatgaag aaagccccac
361 agccactgtt gctgagcagg gagaggatat tacctccaaa aaagacaggg gagtattaaa
421 gattgtcaaa agagtgggga atggtgagga aacgccgatg attggagaca aagtttatgt
481 ccattacaaa ggaaaattgt caaatggaaa gaagtttgat tccagtcatg atagaaatga
541 accatttgtc tttagtcttg gcaaaggcca agtcatcaag gcatgggaca ttggggtggc
601 taccatgaag aaaggagaga tatgccattt actgtgcaaa ccagaatatg catatggctc
661 ggctggcagt ctccctaaaa ttccctcgaa tgcaactctc ttttttgaga ttgagctcct
721 tgatttcaaa ggagaggatt tatttgaaga tggaggcatt atccggagaa ccaaacggaa
781 aggagaggga tattcaaatc caaacgaagg agcaacagta gaaatccacc tggaaggccg
841 ctgtggtgga aggatgtttg actgcagaga tgtggcattc actgtgggcg aaggagaaga
901 ccacgacatt ccaattggaa ttgacaaagc tctggagaaa atgcagcggg aagaacaatg
961 tattttatat cttggaccaa gatatggttt tggagaggca gggaagccta aatttggcat
1021 tgaacctaat gctgagctta tatatgaagt tacacttaag agcttcgaaa aggccaaaga
1081 atcctgggag atggatacca aagaaaaatt ggagcaggct gccattgtca aagagaaggg
1141 aaccgtatac ttcaagggag gcaaatacat gcaggcggtg attcagtatg ggaagatagt
1201 gtcctggtta gagatggaat atggtttatc agaaaaggaa tcgaaagctt ctgaatcatt
1261 tctccttgct gcctttctga acctggccat gtgctacctg aagcttagag aatacaccaa
1321 agctgttgaa tgctgtgaca aggcccttgg actggacagt gccaatgaga aaggcttgta
1381 taggaggggt gaagcccagc tgctcatgaa cgagtttgag tcagccaagg gtgactttga
1441 gaaagtgctg gaagtaaacc cccagaataa ggctgcaaga ctgcagatct ccatgtgcca
1501 gaaaaaggcc aaggagcaca acgagcggga ccgcaggata tacgccaaca tgttcaagaa
1561 gtttgcagag caggatgcca aggaagaggc caataaagca atgggcaaga agacttcaga
1621 aggggtcact aatgaaaaag gaacagacag tcaagcaatg gaagaagaga aacctgaggg
1681 ccacgtatga cgccacgcca aggagggaag agtcccagtg aactcggccc ctcctcaatg
1741 ggctttcccc caactcagga cagaacagtg tttaatgtaa agtttgttat agtctatgtg
1801 attctggaag caaatggcaa aaccagtagc ttcccaaaaa cagcccccct gctgctgccc
1861 ggagggttca ctgaggggtg gcacgggacc actccaggtg gaacaaacag aaatgactgt
1921 ggtgtggagg gagtgagcca gcagcttaag tccagctcat ttcagtttct atcaaccttc
1981 aagtatccaa ttcagggtcc ctggagatca tcctaacaat gtggggctgt taggttttac
2041 ctttgaactt tcatagcact gcagaaacct ttaaaaaaaa aatgcttcat gaatttctcc
2101 tttcctacag ttgggtaggg taggggaagg aggataagct tttgtttttt aaatgactga
2161 agtgctataa atgtagtctg ttgcattttt aaccaacaga acccacagta gaggggtctc
2221 atgtctcccc agttccacag cagtgtcaca gacgtgaaag ccagaacctc agaggccact
2281 tgcttgctga cttagcctcc tcccaaagtc cccctcctca gccagcctcc ttgtgagagt
2341 ggctttctac cacacacagc ctgtccctgg gggagtaatt ctgtcattcc taaaacaccc
2401 ttcagcaatg ataatgagca gatgagagtt tctggattag cttttcctat tttcgatgaa
2461 gttctgagat actgaaatgt gaaaagagca atcagaattg tgctttttct cccctcctct
2521 attcctttta gggaataata ttcaatacac agtacttcct cccagcattg ctactgctca
2581 gcttcttctt tcattctaat ccttgctatt aagaatttaa gacttgtgct tacaatattt
2641 ttgacctgga gtggatctat ttacatagtc atttaggatc catgcagctt tttttgtctt
2701 tttaagatta ttggctcata agcatatgta tactggttta tggaacttta tttacactcc
2761 tctatcatgc aaaaatattt tgacttttta gtactaagct taatttttaa aaacaaaatc
2821 tgtagggttg acaaataaat agttgctctt ctacactagg ggtttcacct gcaggtttga
2881 cacgcagttg ctcgcttttc ctgccctgtc aagcttctct gttctggcgt gagttgtgaa
2941 agagttgaag acagcttccc atgccggtac acagccagta gcctaaatct ccagtacttg
3001 agctgaccat tgaactaggg caagtcttaa atgtgtacat gtagttgaat ttcagtcctt
3061 acgggtaaac agattgagca tggctctcta ttccctcagc ctaagaaaca ctcatgggaa
3121 tgcatttggc aacccaagga accatttgct taaacctgga acatctcacc tttttaaatc
3181 ctaaaaaaca ctggcagtta tattttaaat tagtttttat ttttatgatg gttttatcaa
3241 aagactttta ttattagatt gggaccccct tcaaacctaa aaatcaagtt atttcctttt
3301 ataatacttt tcttccccat ggaacaaatg ggatcaattt gtgagttttt tcctttaatg
3361 ataactaaaa tccctctaat ttctcattta tgcttttgtc ttttttatga aatatttctt
3421 ttaaaagccc cagtctcacc tacgaaatat gaagagcaaa agctgatttt gcttacttgc
3481 taaactgttg ggaaagctct gtagagcatg gttccagtga ggccaagatt gaaatttgat
3541 actaaaaagg ccacctagct ttttgcagat aacaaacaag aaagctattc caagactcag
3601 atgatgccag ctgtctccca cgtgtgtatt atggttcacc agggggaact ggcaaaagtg
3661 tgtgtgggga ggggaagggt gtgtgagtgg ttctgagcaa ataactacag ggtgcccatt
3721 accactcaag aagacacttc acgtattctt gtatcaaatt caataatctt aaacaatttg
3781 tgtagaagtc cacagacatc tttcaaccac cttttaggct gcatatggat tgccaagtca
3841 gcatatgagg aattaaagac attgtttttt aaaaaaaaaa aaaaaaaa
//