LOCUS BC041156 2270 bp mRNA linear HUM 21-OCT-2003
DEFINITION Homo sapiens unc-5 homolog C (C. elegans), mRNA (cDNA clone
MGC:48696 IMAGE:5208108), complete cds.
ACCESSION BC041156
VERSION BC041156.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2270)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2270)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (16-DEC-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 84 Row: d Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 16933524.
FEATURES Location/Qualifiers
source 1..2270
/db_xref="H-InvDB:HIT000052525"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:48696 IMAGE:5208108"
/tissue_type="Lung, Spleen, fetal, pooled"
/clone_lib="NIH_MGC_122"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2270
/gene="UNC5C"
/gene_synonym="UNC5H3"
/db_xref="GeneID:8633"
/db_xref="MIM:603610"
CDS 350..2143
/gene="UNC5C"
/gene_synonym="UNC5H3"
/codon_start=1
/product="UNC5C protein"
/protein_id="AAH41156.1"
/db_xref="GeneID:8633"
/db_xref="MIM:603610"
/translation="MRKGLRATAARCGLGLGYLLQMLVLPALALLSASGTGSAAQDDD
FFHELPETFPSDPPEPLPHFLIEPEEAYIVKNKPVNLYCKASPATQIYFKCNSEWVHQ
KDHIVDERVDETSGLIVREVSIEISRQQVEELFGPEDYWCQCVAWSSAGTTKSRKAYV
RIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEDIIDPVEDRNFYI
IIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIVYVNGGWSTWTEWSVCNSRC
GRGYQKRTRTCTNPAPLNGGAFCEGQSVQKIACTTLCPVDGRWTPWSKWSTCGTECTH
WRRRECTAPAPKNGGKDCDGLVLQSKNCTDGLCMQSFIYPISTEQRTQNEYGFSSAPD
SDDVALYVGIVIAVIVCLAISVVVALFVYRKNHRDFESDIIDSSALNGGFQPVNIKAA
RQDLLAVPPDLTSAAAMYRGPVYALHDVSDKIPMTNSPILDPLPNLKIKVYNTSGAVT
PQDDLSEFTSKLSPQMTQSLLENEALSLKNQSLARQTDPSCTAFGSFNSLGGHLIVPN
SGVSLLIPAGAIPQGRVYEMYVTVHRKETMR"
misc_feature 866..1123
/gene="UNC5C"
/gene_synonym="UNC5H3"
/note="IG; Region: Immunoglobulin"
/db_xref="CDD:smart00409"
misc_feature 1136..1291
/gene="UNC5C"
/gene_synonym="UNC5H3"
/note="TSP1; Region: Thrombospondin type 1 repeats"
/db_xref="CDD:smart00209"
misc_feature 1304..1450
/gene="UNC5C"
/gene_synonym="UNC5H3"
/note="TSP1; Region: Thrombospondin type 1 repeats"
/db_xref="CDD:smart00209"
misc_feature 1988..2140
/gene="UNC5C"
/gene_synonym="UNC5H3"
/note="ZU5; Region: Domain present in ZO-1 and Unc5-like
netrin receptors"
/db_xref="CDD:smart00218"
BASE COUNT 577 a 569 c 585 g 539 t
ORIGIN
1 cagacttcgg cgtgcggcgg agctgcggct gctcctgctg ctggggggag cggcggaggt
61 ggccgccttg cgcctccctg gacttcccaa gtgggggcag agcagtcgct cgcgggagac
121 gtcagttaga aggcattggg aaagagggac cttcaaactc ctcctcggcg tctcctctcc
181 tccccctttt ggcccctgcc tttggagaaa gtggagtgtg gcgcttggtt gtcgttattt
241 cttcggactg cttcgcggtg cacggattca gcttctgccc agtggggctt tcagctgttt
301 gcgcgtctct ctgtccccct cccctccccc cggcacacct ctgtctacga tgaggaaagg
361 tctgcgggcg acagcggccc gctgcggact gggactggga tacttgctgc aaatgctcgt
421 gctacctgcc ctggccctgc tcagcgccag cggcactggc tccgccgccc aagatgatga
481 cttttttcat gaactcccag aaacttttcc ttctgatcca cctgagcctc tgccacattt
541 ccttattgag cctgaagaag cttatattgt gaagaataag cctgtgaacc tgtactgtaa
601 agcaagccct gccacccaga tctatttcaa gtgtaatagc gaatgggttc atcagaagga
661 ccacatagta gatgaaagag tagatgaaac ttccggtctc attgtccggg aagtgagcat
721 tgagatttcg cgccagcaag tggaagaact ctttggacct gaagattact ggtgccagtg
781 tgtggcctgg agctccgcgg gtaccacaaa gagccggaag gcgtatgtgc gcattgcata
841 tctacggaag acatttgagc aggaacccct aggaaaggaa gtgtctttgg aacaggaagt
901 cttactccag tgtcgaccac ctgaagggat cccagtggct gaggtggaat ggttgaaaaa
961 tgaagacata attgatcccg ttgaagatcg gaatttttat attattattg atcacaacct
1021 catcataaag caggcccgac tctctgatac tgcaaattac acctgtgttg ccaaaaacat
1081 tgttgccaag aggaaaagta caactgccac tgtcatagtc tatgtcaacg gtggctggtc
1141 cacctggacg gagtggtctg tgtgtaacag ccgctgtgga cgagggtatc agaaacgtac
1201 aaggacttgt accaacccgg caccactcaa tgggggtgcc ttctgtgaag ggcagagtgt
1261 gcagaaaata gcctgtacta cgttatgccc agtggatggc aggtggacgc catggagcaa
1321 gtggtctact tgtggaactg agtgcaccca ctggcgcagg agggagtgca cggcgccagc
1381 ccccaagaat ggaggcaagg actgcgacgg cctcgtcttg caatccaaga actgcactga
1441 tgggctttgc atgcagagtt tcatttatcc catttcaact gaacagagaa cccagaatga
1501 atatggattt tcttctgctc ctgattcaga tgatgttgct ctctatgttg ggattgtgat
1561 agcagtgatc gtttgcctgg cgatctctgt agttgtggcc ttgtttgtgt atcggaagaa
1621 tcatcgtgac tttgagtcag atattattga ctcttcggca ctcaatgggg gctttcagcc
1681 tgtgaacatc aaggcagcaa gacaagatct gctggctgta cccccagacc tcacgtcagc
1741 tgcagccatg tacagaggac ctgtctatgc cctgcatgac gtctcagaca aaatcccaat
1801 gaccaactct ccaattctgg atccactgcc caacctgaaa atcaaagtgt acaacacctc
1861 aggtgctgtc accccccaag atgacctctc tgagtttacg tccaagctgt cccctcagat
1921 gacccagtcg ttgttggaga atgaagccct cagcctgaag aaccagagtc tagcaaggca
1981 gactgatcca tcctgtaccg catttggcag cttcaactcg ctgggaggtc accttattgt
2041 tcccaattca ggagtcagct tgctgattcc cgctggggcc attccccaag ggagagtcta
2101 cgaaatgtat gtgactgtac acaggaaaga aactatgagg taaatatgct ttttctggtg
2161 cactgacttt accaatgtct aacttggagg agaattgtac aatagacaca ataaacccaa
2221 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//