LOCUS BC041063 2982 bp mRNA linear HUM 11-AUG-2006
DEFINITION Homo sapiens eyes absent homolog 4 (Drosophila), mRNA (cDNA clone
MGC:52237 IMAGE:5458911), complete cds.
ACCESSION BC041063
VERSION BC041063.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2982)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2982)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (13-DEC-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 44 Row: k Column: 9
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 26667248.
FEATURES Location/Qualifiers
source 1..2982
/db_xref="H-InvDB:HIT000052491"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:52237 IMAGE:5458911"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_47"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2982
/gene="EYA4"
/db_xref="GeneID:2070"
/db_xref="HGNC:HGNC:3522"
/db_xref="MIM:603550"
CDS 398..2248
/gene="EYA4"
/codon_start=1
/product="eyes absent homolog 4 (Drosophila)"
/protein_id="AAH41063.1"
/db_xref="GeneID:2070"
/db_xref="HGNC:HGNC:3522"
/db_xref="MIM:603550"
/translation="MEDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGG
GDTPGSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDTFTGSVI
TSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQ
TGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMP
GSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNT
ADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGSKSRGRGRK
NNPSPPPDSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFN
LADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRG
GVDWMRKLAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALK
SLSIISTRSNCINVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIM
QRFGRKVVYVVIGDGVEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL"
BASE COUNT 864 a 660 c 660 g 798 t
ORIGIN
1 gggaaaagcc ggggagtgac gactgcggcg gctgggcgcg ctctctcatt ttcttttctt
61 ctcctttccc ccctgtcgca gtccggagtt ttggctcctc tcctttcctc ctccccctcg
121 gagccggctt ctccctccgc cccgcttctc ccccgcttgt gtacgctatt tgttgtgggg
181 tggccgaagg ggatgtcctg ttttcaccag aggcacagcg cgaaggggaa acttcgacac
241 tggaaggaac gagaataaat acttaattac ggacgcactg aaccgcggct gggacagaca
301 cttcgggaac ccgaggcgga ccgggcgacg agatagtcat ttttacttga aggaagctgc
361 ttctacttgg gagtggcagg agaagtgaga aaaccacatg gaagactccc aggatttaaa
421 tgaacaatca gtaaagaaaa cgtgcacaga atcagatgtt tcacaatctc agaattccag
481 gtctatggaa atgcaggacc tagcaagtcc tcatactctt gttggaggtg gtgatactcc
541 aggtagctcc aaactggaaa aatctaatct cagcagcaca tcagttacta caaatgggac
601 aggagtgtct cttcttgcag tcaaaacaga gcccttgaac agcagtgaaa ccacagccac
661 gactggagat ggagcgcttg acacttttac tgggtcagta attacaagta gtggctacag
721 ccccagatca gcacatcagt attccccaca gctgtatcct tccaagccct atccacacat
781 tctttctaca ccagcagctc aaacaatgtc tgcctatgca ggccagactc agtattcggg
841 gatgcagcag ccagccgtct acacagccta ctcacagaca ggacagccct acagcttgcc
901 cacttacgat ttgggtgtga tgttgccagc catcaagaca gagagtggac tttcccaaac
961 tcagtcccca ttacagagtg gctgcctcag ttacagccca gggttctcta ccccacagcc
1021 aggccagaca ccttattctt accaaatgcc aggttctagt tttgcaccat catctactat
1081 ttatgcaaat aattcagttt ccaattcaac aaatttcagt ggttcacaac aggattatcc
1141 atcctataca gcctttggcc aaaaccagta tgcacagtat tattcagcat caacgtatgg
1201 agcgtatatg acatcgaata acacagccga tggcacaccc tcttcaacct ctacttatca
1261 gttgcaggaa tctctcccag gactgactaa ccaaccagga gagttcgata ccatgcagag
1321 tccctccaca cccatcaaag atcttgatga gagaacctgt aggagttctg ggtcaaagtc
1381 cagaggaaga ggccggaaaa ataatccctc cccgcctcct gatagtgacc tggagcgtgt
1441 gtttgtctgg gatttggatg aaaccatcat tgtttttcac tcactgctca ccgggtctta
1501 tgcacagaag tatggcaagg atccccccat ggctgtaacc cttggactcc gcatggaaga
1561 aatgattttt aatcttgctg atactcattt gttttttaat gatttagagg agtgtgatca
1621 agttcatata gatgatgttt cctctgatga taatgggcag gacttaagta cctacagttt
1681 tgcaactgat ggcttccatg cagctgcaag tagtgcaaac ctttgtttgc caacaggtgt
1741 aagaggaggg gttgactgga tgaggaagtt ggcttttcgt tacagaagag taaaagaatt
1801 atataacacc tacaagaaca acgttggagg actccttggc cctgccaaga gggatgcctg
1861 gctacagtta agggcagaga ttgaaggtct gacagattcc tggctaacaa atgcacttaa
1921 gtctttatca attattagca ctaggagtaa ctgcataaat gtcttggtaa cgacaactca
1981 actgatccca gcacttgcga aggttctact ctatagttta ggaggtgctt tccccattga
2041 gaatatttac agtgcaacta aaataggaaa agaaagttgc tttgaacgaa taatgcaaag
2101 gtttggcaga aaagtagtgt atgttgtaat tggggatggt gtagaagaag aacaggcagc
2161 aaaaaagcac aacatgccct tctggaggat atccagtcac tcagacctcc tggctctcca
2221 ccaagcactg gaattagagt atttgtaact gtgttcttta gccggagatc tattttttat
2281 atttcaagta cactgaattt ttatgtgtga ttcaatgcct ctggctctac acatataaat
2341 tgtcttaatg gatgaaatca tatttggaat aaaaattcca gaatgaagaa ttcagattgc
2401 tgaatggagt taaactttag tgctacagaa aagaaactct atggtcttat atttacaaca
2461 ctttaatggg ttttttaaaa atctgtggag gttgctggta cacaccaaat gagtccaaac
2521 tggaatgagc agctttagca aagaactctt acctggcaaa gcagcaacac acatgctccg
2581 tctgacaagg tggtcaacaa cattcctcaa aatgggagat cttctcagcc ctgaggtttg
2641 aatctgactt tagcctacct aacccagaaa atctgaattg gaatgcactc agactgtata
2701 aggacagtcc tatttagaca tgtaatttgt gtaaattatt gatgaaaata atttactgtg
2761 actttattag cagctgactt tcaaagtgga tgcaattttt ctttcttttg ttggggaggg
2821 gaatgggagg ggaaatggga atataatatt gtctcttttt taagtttggc aaacagaatg
2881 ttcatactga tgtgttgtgc cttaaagaca agacagcatt tgtgtgttac aatgtaactt
2941 tggttaaaat ctctgtagat aatgaaaaaa aaaaaaaaaa aa
//