LOCUS BC041049 2024 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens mitogen-activated protein kinase-activated protein
kinase 5, mRNA (cDNA clone MGC:52129 IMAGE:4909021), complete cds.
ACCESSION BC041049
VERSION BC041049.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2024)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2024)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (13-DEC-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 44 Row: g Column: 23
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21237764.
FEATURES Location/Qualifiers
source 1..2024
/db_xref="H-InvDB:HIT000052487"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:52129 IMAGE:4909021"
/tissue_type="Pancreas, epithelioid carcinoma"
/clone_lib="NIH_MGC_42"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2024
/gene="MAPKAPK5"
/gene_synonym="PRAK"
/db_xref="GeneID:8550"
/db_xref="HGNC:HGNC:6889"
/db_xref="MIM:606723"
CDS 494..1909
/gene="MAPKAPK5"
/gene_synonym="PRAK"
/codon_start=1
/product="mitogen-activated protein kinase-activated
protein kinase 5"
/protein_id="AAH41049.1"
/db_xref="GeneID:8550"
/db_xref="HGNC:HGNC:6889"
/db_xref="MIM:606723"
/translation="MSEESDMDKAIKETSILEEYSINWTQKLGAGISGPVRVCVKKST
QERFALKILLDRPKARNEVRLHMMCATHPNIVQIIEVFANSVQFPHESSPRARLLIVM
EMMEGGELFHRISQHRHFTEKQASQVTKQIALALRHCHLLNIAHRDLKPENLLFKDNS
LDAPVKLCDFGFAKIDQGDLMTPQFTPYYVAPQVLEAQRRHQKEKSGIIPTSPTPYTY
NKSCDLWSLGVIIYVMLCGYPPFYSKHHSRTIPKDMRRKIMTGSFEFPEEEWSQISEM
AKDVVRKLLKVKPEERLTIEGVLDHPWLNSTEALDNVLPSAQLMMDKAVVAGIQQAHA
EQLANMRIQDLKVSLKPLHSVNNPILRKRKLLGTKPKDSVYIHDHENGAEDSNVALEK
LRDVIAQCILPQAGENEDEKLNEVMQEAWKYNRECKLLRDTLQSFSWNGRGFTDKVDR
LKLAEIVKQVIEEQTTSHESQ"
BASE COUNT 531 a 524 c 551 g 418 t
ORIGIN
1 gtggcgctga ggcggcggcg ggagcagcgg cgccgagctc tgcttcggct tcggcttcgg
61 cttcgcggcg gtgcaggcgg cggaggcgga ggcgcaggct cttctttagg acctggcgag
121 cccaggtcta agcggcggcc ccgcgaggcc cttgcacggc gccccgggtc gaggccctcc
181 ccgcctcgcc ctaccccagg agcctgcctc cccagctggg gatgaggcta ggaggcggcc
241 gcgtggggcc cagcacaaag acctgtcccc aggggccgcc gcctccgccg ctgctgctgc
301 cgccagccta gagccgcccg ccgaagcaga gccggcgccg gggtcctcat ccccaccggt
361 cccgaggggc ggctgctgcc cgtcgccacg aggcccaggg gcccgagtgc cgagcccttt
421 gctccctcgg ccgcgcgggg acagggctgc tgagcagcct ccgcctctcc cggctgtggg
481 ggccccactg agtatgtcgg aggagagcga catggacaaa gccatcaagg aaacttccat
541 tttagaagaa tacagtatca attggactca gaagctggga gctggaatta gtggtccagt
601 tagagtctgt gtaaagaaat ctactcaaga acggtttgcg ctgaaaattc ttcttgatcg
661 tccaaaagct agaaatgagg tacgtctgca catgatgtgt gccacacacc caaacatagt
721 tcagattatt gaagtgtttg ctaacagtgt ccagtttccc catgagtcca gccctagggc
781 ccgactctta attgtaatgg agatgatgga agggggagag ctatttcaca gaatcagcca
841 gcaccggcac tttacagaga agcaagccag ccaagtaaca aagcagatag ctttggctct
901 gcggcactgt cacttgttaa acattgcgca cagagacctc aagcctgaaa atctgctttt
961 taaggataac tctttggatg ccccagtgaa gttgtgtgac tttggatttg ccaagattga
1021 ccaaggtgac ttgatgacac cccagttcac cccttattat gtagcacccc aggtactgga
1081 ggcgcaaaga aggcatcaga aggagaaatc tggcatcata cctacctcac cgacgcccta
1141 cacttacaac aagagctgtg acttgtggtc cctaggggtg attatctatg tgatgctgtg
1201 cggataccct cctttttact ccaaacacca cagccggact atcccaaagg atatgcgaag
1261 aaagatcatg acaggcagtt ttgagttccc agaggaagag tggagtcaga tctcagagat
1321 ggccaaagat gttgtgagga agctcctgaa ggtcaaaccg gaggagagac tcaccatcga
1381 gggagtgctg gaccacccct ggctcaattc caccgaggcc ctggataatg tgctgccttc
1441 tgctcagctg atgatggaca aggcagtggt tgcaggaatc cagcaggctc acgcggaaca
1501 gttggccaac atgagaatcc aggatctgaa agtcagcctc aaacccctgc actcagtgaa
1561 caaccccatt ctgcggaaga ggaagttact tggcaccaag ccaaaggaca gtgtctatat
1621 ccacgaccat gagaatggag ccgaggattc caatgttgcc ttggaaaaac tccgagatgt
1681 gattgctcag tgtattctcc cccaggctgg agagaatgaa gatgagaaac tgaatgaagt
1741 aatgcaggag gcttggaagt ataaccggga atgcaaactc ctaagagata ctctgcagag
1801 cttcagctgg aatggtcgtg gattcacaga taaagtagat cgactaaaac tggcagaaat
1861 tgtgaagcag gtgatagaag agcaaaccac gtcccacgaa tcccaataat gacagcttca
1921 gactttgttt ttttaacaat ttgaaaaatt attctttaat gtataaagta attttatgta
1981 aattaataaa tcataatttc atttccaaaa aaaaaaaaaa aaaa
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