LOCUS BC040961 3459 bp mRNA linear HUM 07-OCT-2003
DEFINITION Homo sapiens neurogenic differentiation 4, mRNA (cDNA clone
MGC:48946 IMAGE:5490979), complete cds.
ACCESSION BC040961
VERSION BC040961.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3459)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3459)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (06-DEC-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 84 Row: f Column: 23.
FEATURES Location/Qualifiers
source 1..3459
/db_xref="H-InvDB:HIT000052471"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:48946 IMAGE:5490979"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3459
/gene="NEUROD4"
/gene_synonym="ATH-3"
/gene_synonym="Atoh3"
/gene_synonym="MATH-3"
/db_xref="GeneID:58158"
CDS 97..864
/gene="NEUROD4"
/gene_synonym="ATH-3"
/gene_synonym="Atoh3"
/gene_synonym="MATH-3"
/codon_start=1
/product="NEUROD4 protein"
/protein_id="AAH40961.1"
/db_xref="GeneID:58158"
/translation="MTKARLERFRARRVKANARERTRMHGLNDALDNLRRVMPCYSKT
QKLSKIETLRLARNYIWALSEVLETGQTPEGKGFVEMLCKGLSQPTSNLVAGCLQLGP
QSVLLEKHEDKSPICDSAISVHNFNYQSPGLPSPPYGHMETHLLHLKPQVFKSLGESS
FGSHLPDCSTPPYEGPLTPPLSISGNFSLKQDGSPDLEKSYSFMPHYPSSSLSSGHVH
STPFQAGTPRYDVPIDMSYDSYPHHGIGTQLNTVFTE"
misc_feature 130..285
/gene="NEUROD4"
/gene_synonym="ATH-3"
/gene_synonym="Atoh3"
/gene_synonym="MATH-3"
/note="HLH; Region: Helix-loop-helix DNA-binding domain"
/db_xref="CDD:pfam00010"
BASE COUNT 1056 a 697 c 629 g 1077 t
ORIGIN
1 agcagcttaa ctgaagagca tgacagtatt gaggaagaag aagaagagga agaagatggg
61 gagaaaccta agagaagggg tcccaagaaa aagaagatga ccaaagctcg ccttgagaga
121 ttcagggctc gaagagtcaa ggctaatgcc agagaacgga cccggatgca tggcctgaat
181 gacgccctgg ataacctgag gcgagtcatg ccatgctact ctaaaaccca aaaactttcc
241 aagatagaga ctcttagact ggccaggaac tatatttggg ctttatctga agtcctggag
301 actggccaga cacctgaagg gaaaggcttt gtggagatgc tgtgtaaagg gctctctcag
361 cccacaagca acctggtggc tggatgtctc caactgggcc ctcagtctgt cctcctggag
421 aagcacgagg ataaatctcc tatttgtgac tctgccatct ctgtccacaa cttcaactat
481 cagtctccgg ggcttcctag ccctccttat ggtcatatgg aaacacatct ccttcatctc
541 aagccccaag tattcaagag tttgggagaa tcgtcctttg ggagccatct gcctgactgc
601 agtacacccc cttatgaggg cccactcact ccacccctga gcatcagtgg gaacttctcc
661 ttgaagcaag atgggtctcc tgacctagaa aaatcctaca gcttcatgcc acattaccct
721 tcttcaagtc taagctcagg gcatgtgcat tcaactcctt ttcaggctgg taccccccgt
781 tatgatgttc ctatagacat gtcctatgat tcctaccccc atcatggtat tgggacccaa
841 ctcaatacag tcttcactga gtgaggcagt taagttcaat gtttcagaga atgacgtgga
901 gacattttcc ataattcaag tggttgagct aaagattcaa tgaccttaaa ggatccctat
961 ggatatatat caaacaatag ttcaagtcca tttaggcttt ccttcaccta tcacctcttt
1021 tctcatcacc ttctcacatt gcattgattt ctttatagag tcctcaagtg aaaatatttg
1081 atgatttaac aaccatgtga aaatagaaca gaagacctgg gccctattcc agtggtgcca
1141 aaaactcatt gcataatctg tgccaattaa ttttccattt ctggcctttg tttatttact
1201 agcaattgta aataaacaaa ttgtatttat atgaggcaac tattctaagt ccagatgatt
1261 tctaaagtcc ttcacagttc tgaaatgcta taactgtggt gatcactctt gacaatttct
1321 tgaaactgaa agaatagaga aataatagga aagggatgct atgcatagaa tgatcaaatt
1381 gaattatcag agggatcaca aggtacatgt ctcttggctc acagaatgca aagcttgttt
1441 ggatttaatg ataggacctc tttgtatcta ttgaaaaata gcttctggaa gctaaaagtc
1501 taacatggct gtcactgtga agaacaaaac atgttcgtta agagactaac tctatttgtt
1561 attagactaa aagttgaaca tatcttcctt atgatttgaa gaaccataat agagaaccat
1621 aatagaggcc tcatgccaac tttattcttg ataatatttc aaaaccattt ttctcagtac
1681 tagaggtagg gcaaacaagt cactgaagcc tcagactcct ataactaatg ggacatagag
1741 aagtctttta gaccatgacc tccataacca gagggctctg gaacttctga tgaagctcag
1801 gtgctgctgt tagaatcagc acacaacaca ggtttatatt aaagagcaat aaaatagcta
1861 ttggctataa taactactat agttcaggga ctctctccag ctcacagttg cccatgggaa
1921 aaaccaatgg attttttttt aagcaagatg aatttcattt ggttaaacgt gattaaaacc
1981 atccacctct gtccacacca atatattttc cagaagcaca agcaccaatc aatttattga
2041 tcaaggttaa atttttccaa catatatgta gttccttatc tctcccccta cactaattgt
2101 tacctcttcc tcacttctaa gatagaatat gttattatat attgtaaata acatttcagg
2161 tgaccaaact taaggatgca gaaatgaaat ccaaggttgg tgaatatttt taccaactat
2221 gtcttcatca caggtttaac ccaatttgca gagtgtttat ttttctttat gtaactcctt
2281 tttcctttat atcaatgcta acttcatcaa atttgtattt tttttcagaa aatgggacct
2341 gagaaatttt cctatcttgt tcaatcagcc aggacagtta tttaagtcaa accagagcct
2401 gaatggctta tttgatagta gattaggtcc tgctcctgcc agaaaggata agtttaacat
2461 gcagggtaca tcaatagggc caatttaaaa aatgataaca catattagta tgtcattttc
2521 tatagctcag ctatccccta aaatctgcca actatatgtg tatcttgtct gtttacctct
2581 cttatttatt atctccatac agtataagtt attttttttc cattttgctc tcagcactta
2641 ccctgctgta ttttgcaccc ttggtttgta aattcacttg aaagtagcct tgcagagaga
2701 tcttaagccc catcagtcac caaagtggtt cccttcatca caatctgccc tagaggaaat
2761 aggcaagtaa aatgatatat aaagccatac tatgtgcttt ctgagtatat actgcactta
2821 cctttgtgag cggctgtagg agggtctatc ctcgaagcta gcattttctg gcatttaagt
2881 ttgtagataa tcactgttgt ttgagttatt tattagatat tatttattta atttatttct
2941 ctcttccttt cacgaaaatt cctttagccc catagatgtg cttgcaaacc cttcctaaaa
3001 ttttatttgg aaagtagctc ataattttgc taagaactgc tgagttttgg agtgagggga
3061 aagaaaaaaa tagagaatta cctctgtgat aatttttata aaaagcagca ataattcgaa
3121 tggctatgca agttaatgtt tttagagtct tttcttcagt ctaaaatgag ccagagttat
3181 tctttaataa tctgctgttt atgcctttgg ggagtatggt acccatgagc caagcctccc
3241 tgaaattgta cagagggatt ttataattga attaaaattt aggaatgcaa tagcttgtaa
3301 agagcctgct ctccaacata gggtggtctc attcttctgg agactttttt agataaagta
3361 aaataattgt ttaaatattt tgtttaaaat atgactgttt ttcctccctt tttcctagca
3421 gaaataaagc tgtaagtctt attaaaaaaa aaaaaaaaa
//