LOCUS BC040520 5567 bp mRNA linear HUM 28-JUL-2005
DEFINITION Homo sapiens nephronophthisis 4, mRNA (cDNA clone MGC:39505
IMAGE:5295140), complete cds.
ACCESSION BC040520
VERSION BC040520.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5567)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 5567)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-NOV-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 63 Row: l Column: 7
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 34304361.
FEATURES Location/Qualifiers
source 1..5567
/db_xref="H-InvDB:HIT000052412"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:39505 IMAGE:5295140"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..5567
/gene="NPHP4"
/gene_synonym="KIAA0673"
/gene_synonym="SLSN4"
/db_xref="GeneID:261734"
/db_xref="MIM:607215"
CDS 270..3005
/gene="NPHP4"
/gene_synonym="KIAA0673"
/gene_synonym="SLSN4"
/codon_start=1
/product="NPHP4 protein"
/protein_id="AAH40520.1"
/db_xref="GeneID:261734"
/db_xref="MIM:607215"
/translation="MNDWHRIFTQNVLVPPHPQRARQPWKESTAFQCVLKWLDGPVIR
QGVLEVLSEVECHLRVSFFDVTYRHFFGRTWKTTVKPTKRPPSRIVFNEPLYFHTSLN
HPHIVAVVEVVAEGKKRDGSLQTLSCGFGILRIFSNQPDSPISASQDKRLRLYHGTPR
ALLHPLLQDPAEQNRHMTLIENCSLQYTLKPHPALEPAFHLLPENLLVSGLQQIPGLL
PAHGESGDALRKPRLQKPITGHLDDLFFTLYPSLEKFEEELLELHVQDHFQEGCGPLD
GGALEILERRLRVGVHNGLGFVQRPQVVVLVPEMDVALTRSASFSRKVVSSSKTSSGS
QALVLRSRLRLPEMVGHPAFAVIFQLEYVFSSPAGVDGNAASVTSLSNLACMHMVRWA
VWNPLLEADSGRVTLPLQGGIQPNPSHCLVYKVPSASMSSEEVKQVESGTLRFQFSLG
SEEHLDAPTEPVSGPKVERRPSRKPPTSPSSPPAPVPRVLAAPQNSPVGPGLSISQLA
ASPRSPTQHCLARPTSQLPHGSQASPAQAEFPLEAGISHLEADLSQTSLVLETSIAEQ
LQELPFTPLHAPIVVGTQTRSSAGQPSRASMVLLQSSGFPEILDANKQPAEAVSATEP
VTFNPQKEESDCLQSNEMVLQFLAFSRVAQDCRGTSWPKTVYFTFQFYRFPPATTPRL
QLVQLDEAGQPSSGALTHILVPVSRDGTFDAGSPGFQLRYMVGPGFLKPGERRCFARY
LAVQTLQIDVWDGDSLLLIGSAAVQMKHLLRQGRPAVQASHELEVVATEYEQDNMVVS
GDMLGFGRVKPIGVHSVVKGRLHLTLANVGHPCEQKVRGCSTLPPSRSRVISNDGASR
FSGGSLLTTGSSRRWALQATVLFGEVGTLPVAFVSGWLLICKGRRNGEKVRRNID"
BASE COUNT 1119 a 1667 c 1638 g 1143 t
ORIGIN
1 ggtgacgcga ggcgggttct tggactgagt gtgcggcgcg gtgcgccgcc ttccgaggct
61 cctcccgcgg gtggcagcgg acggggcgcg cccctcggcc agtcctcggt cctcaggctt
121 gtggctccgt tgagcaccgg ccgccgggcc tctgggtccg tcgagtggag actctctgaa
181 aagcgtgggc tccgtggcct ccggcgcggc cgcggcgggt cggtctccta gatcatccgg
241 gaagcccacg ggaccctcag gcgggcagga tgaacgactg gcacaggatc ttcacccaaa
301 acgtgcttgt ccctccccac ccacagagag cgcgccagcc ttggaaggaa tccacggcat
361 tccagtgtgt cctcaagtgg ctggacggac cggtaattag gcagggcgtg ctggaggtac
421 tgtcagaggt tgaatgccat ctgcgagtgt ctttctttga tgtcacctac cggcacttct
481 ttgggaggac gtggaaaacc acagtgaagc cgacgaagag accgccgtcc aggatcgtct
541 ttaatgagcc cttgtatttt cacacatccc taaaccaccc tcatatcgtg gctgtggtgg
601 aagtggtcgc tgagggcaag aaacgggatg ggagcctcca gacattgtcc tgtgggtttg
661 gaattcttcg gatcttcagc aaccagccgg actctcctat ctctgcttcc caggacaaaa
721 ggttgcggct gtaccatggc acccccagag ccctcctgca cccgcttctc caggaccccg
781 cagagcaaaa cagacacatg accctcattg agaactgcag cctgcagtac acgctgaagc
841 cacacccggc cctggagcct gcgttccacc ttcttcctga gaaccttctg gtgtctggtc
901 tgcagcagat acctggcctg cttccagctc atggagaatc cggcgacgct ctccgaaagc
961 ctcgcctcca gaagcccatc acggggcact tggatgactt attcttcacc ctgtacccct
1021 ccctggagaa gtttgaggaa gagctgctgg agctccacgt ccaggaccac ttccaggagg
1081 gatgtggccc actggacggt ggtgccctgg agatcctgga gcggcgcctg cgtgtgggcg
1141 tgcacaatgg tctgggcttc gtgcagaggc cgcaggtcgt tgtactggtg cctgagatgg
1201 atgtggcctt gacgcgctca gctagcttca gcaggaaagt ggtctcctct tccaagacca
1261 gctccgggag ccaagctctg gttttgagaa gccgcctccg cctcccagag atggtcggcc
1321 accctgcatt tgcggtcatc ttccagctgg agtacgtgtt cagcagccct gcaggagtgg
1381 acggcaatgc agcttcggtc acctctctgt ccaacctggc atgcatgcac atggtccgct
1441 gggctgtttg gaaccccttg ctggaagctg attctggaag ggtgaccctg cctctgcagg
1501 gtgggatcca gcccaacccc tcgcactgtc tggtctacaa ggtaccctca gccagcatga
1561 gctctgaaga ggtgaagcag gtggagtcgg gtacactccg gttccagttc tcgctgggct
1621 cagaagaaca cctggatgca cccacggagc ctgtcagtgg ccccaaagtg gagcggcggc
1681 cttccaggaa accacccacg tccccttcga gcccgccagc gccagtacct cgagttctcg
1741 ctgccccgca gaactcacct gtgggaccag ggttgtcaat ttcccagctg gcggcctccc
1801 cgcggtcccc gactcagcac tgcttggcca ggcctacttc acagctaccc catggctctc
1861 aggcctcccc ggcccaggca gagttcccgt tggaggccgg tatctcccac ctggaagccg
1921 acctgagcca gacctccctg gtcctggaaa catccattgc cgaacagtta caggagctgc
1981 cgttcacgcc tttgcatgcc cctattgttg tgggaaccca gaccaggagc tctgcagggc
2041 agccctcgag agcctccatg gtgctcctgc agtcctccgg ctttcccgag attctggatg
2101 ccaataaaca gccagccgag gctgtcagcg ctacagaacc tgtgacgttt aaccctcaga
2161 aggaagaatc agattgtcta caaagcaacg agatggtgct acagtttctt gcctttagca
2221 gagtggccca ggactgccga ggaacatcat ggccaaagac tgtgtatttc accttccagt
2281 tctaccgctt cccacccgca acgacgccac gactgcagct ggtccagctg gatgaggccg
2341 gccagcccag ctctggcgcc ctgacccaca tcctcgtgcc tgtgagcaga gatggcacct
2401 ttgatgctgg gtctcctggc ttccagctga ggtacatggt gggccctggg ttcctgaagc
2461 caggtgagcg gcgctgcttt gcccgctacc tggccgtgca gaccctgcag attgacgtct
2521 gggacggaga ctccctgctg ctcatcggat ctgctgccgt ccagatgaag catctcctcc
2581 gccaaggccg gccggctgtg caggcctccc acgagcttga ggtcgtggca actgaatacg
2641 agcaggacaa catggtggtg agtggagaca tgctggggtt tggccgcgtc aagcccatcg
2701 gcgtccactc ggtggtgaag ggccggctgc acctgacttt ggccaacgtg ggtcacccgt
2761 gtgaacagaa agtgagaggt tgtagcacat tgccaccgtc cagatctcgg gtcatctcaa
2821 acgatggagc cagccgcttc tctggaggca gcctcctcac gactggaagc tcaaggcgct
2881 gggctctgca ggcgactgtg ctgtttggag aagtgggaac cctgccagtg gcatttgtgt
2941 ctggttggct gctcatctgc aagggaagga gaaatggaga gaaggtcagg aggaacatag
3001 actgattttc aaaacaagtt gaagtcccct atgttgtgaa cagaagaaag aagccaatta
3061 tggagcttgg gaaagaaaga cctggtttgg agaggaagac ctgggtttgg tgaaaatgtg
3121 tttcacagca gggaggctct gaagtttttc tatcccctta aaatgaaaac acgtggtgca
3181 agcacagaag ctggcggacg tggacagtga gctggctgcc atgctactga cccatgcccg
3241 gcagggcaag gggccccagg acgtcagccg cgagtcggat gccacccgca ggcgtaagct
3301 ggagcggatg aggtctgtgc gcctgcagga ggccggggga gacttgggcc ggcgtgggac
3361 gagcgtgttg taaactcagc agggctgcca ctcagcctcc ctgccagcaa ggcgttggtg
3421 ctcaaaggtg gatgcagacg cctcggtccc tccctaggct cagttcagtc tgatggggcg
3481 aggaagaggc atggtgagaa gacacgggca cagcctgtca gaggttccac tcctgaaaag
3541 ctctgaggat gaaattctga tggaggcccc aagtgtgaaa ggccagctcc aatccccctg
3601 caaaggaaca gccagagcct tggatgttgg aaagcgcagc agagcgtccg cacacagcac
3661 ttgcgggacc tacaggtcat cgccgcctac cgggaacgca cgaaggccga gagcatcgcc
3721 agcctgctga gcctggccat caccacggag cacacgctcc acgccacgct gggggtcgcc
3781 gagttctttg agtttgtgct taagaacccc cacaacacac agcacacggt gactgtggag
3841 atcgacaacc ccgagctcag cgtcatcgtg gacagtcagg agtggaggga cttcaagggt
3901 gctgctggcc tgcacacacc ggtggaggag gacatgttcc acctgcgtgg cagcctggcc
3961 ccccagctct acctgcgccc ccacgagacc gcccacgtcc ccttcaagtt ccagagcttc
4021 tctgcagggc agctggccat ggtgcaggcc tctcctgggt tgagcaacga gaagggcatg
4081 gacgccgtgt caccttggaa gtccagcgca gtgcccacta aacacgccaa ggtcttgttc
4141 cgagcgagtg gtggcaagcc catcgccgtg ctctgcctga ctgtggagct gcagccccac
4201 gtggtggacc aggtcttccg cttctatcac ccggagctct ccttcctgaa gaaggccatc
4261 cgcctgccgc cctggcacac atttccaggt gctccggtgg gaatgcttgg tgaggacccc
4321 ccagtccatg ttcgctgcag cgacccgaac gtcatctgtg agacccagaa tgtgggcccc
4381 ggggaaccac gggacatatt tctgaaggtg gccagtggtc caagcccgga gatcaaagac
4441 ttctttgtca tcatttactc ggatcgctgg ctggcgacac ccacacagac gtggcaggtc
4501 tacctccact ccctgcagcg cgtggatgtc tcctgcgtcg caggccagct gacccgcctg
4561 tcccttgtcc ttcgggggac acagacagtg aggaaagtga gagctttcac ctctcatccc
4621 caggagctga agacagaccc caaaggtgtc ttcgtgctgc cgcttcgtgg ggtgcaggac
4681 ctgcatgttg gcgtgaggcc ccttagggcc ggcagccgct ttgtccatct caacctggtg
4741 gacgtggatt gccaccagct ggtggcctcc tggctcgtgt gcctctgctg ccgccagccg
4801 ctcatctcca aggcctttga gatcatgttg gctgcgggcg aagggaaggg tgtcaacaag
4861 aggatcacct acaccaaccc ctacccctcc cggaggacat tccacctgca cagcgaccac
4921 ccggagctgc tgcggttcag agaggactcc ttccaggtcg ggggtggaga gacctacacc
4981 atcggcttgc agtttgcgcc tagtcagaga gtgggtgagg aggagatcct gatctacatc
5041 aatgaccatg aggacaaaaa cgaagaggca ttttgcgtga aggtcatcta ccagtgaggg
5101 cttgagggtg acgtccttcc tgcggcaccc agctggggcc tgtctgtgcc cctcctgccc
5161 tgcaggctgt cctccccgcc tctctgcagc ctttcacttc agtgcccacc tggctgacct
5221 gtgcacttgg ctgaggaagc agagaccgag cgctggtcat tttgtagtac ctgcatccag
5281 cttagctgct gctgacaccc agcaggcctg ggttccgtga gcgcgaactc cgtggtggtg
5341 ggtctggctc tggtgctgcc atctacgcat gtgggaccct cgttatcgct gttgctcaaa
5401 atgtatttta tgaatcatcc taaatgagaa aattatgttt ttcttactgg attttgtaca
5461 aacataatct attatttgct atgcaatatt ttatgctggt attatatctg ttttttaaat
5521 tgttgaacaa aatactaaac ttttacacgc caaaaaaaaa aaaaaaa
//