LOCUS BC040457 4807 bp mRNA linear HUM 18-MAR-2009
DEFINITION Homo sapiens calcium/calmodulin-dependent protein kinase II alpha,
mRNA (cDNA clone MGC:26106 IMAGE:4811948), complete cds.
ACCESSION BC040457
VERSION BC040457.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4807)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4807)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-NOV-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 32 Row: j Column: 12
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 25952113.
FEATURES Location/Qualifiers
source 1..4807
/db_xref="H-InvDB:HIT000052392"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:26106 IMAGE:4811948"
/tissue_type="Brain, hippocampus"
/clone_lib="NIH_MGC_95"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..4807
/gene="CAMK2A"
/db_xref="GeneID:815"
/db_xref="HGNC:HGNC:1460"
/db_xref="MIM:114078"
CDS 131..1567
/gene="CAMK2A"
/codon_start=1
/product="calcium/calmodulin-dependent protein kinase II
alpha"
/protein_id="AAH40457.1"
/db_xref="GeneID:815"
/db_xref="HGNC:HGNC:1460"
/db_xref="MIM:114078"
/translation="MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKII
NTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIV
AREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLA
IEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQ
HRLYKQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRST
VASCMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSGGKSGGNKKSDGVKESSEST
NTTIEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGL
DFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSE
ETRVWHRRDGKWQIVHFHRSGAPSVLPH"
BASE COUNT 1048 a 1337 c 1277 g 1145 t
ORIGIN
1 agtcaaaccg gttctctgtt tgcactcggc agcacgggca ggcaagtggt ccctaggttc
61 gggagcagag cagcagcgcc tcagtcctgg tcccccagtc ccaagcctca cctgcctgcc
121 cagcgccagg atggccacca tcacctgcac ccgcttcacg gaagagtacc agctcttcga
181 ggaattgggc aagggagcct tctcggtggt gcgaaggtgt gtgaaggtgc tggctggcca
241 ggagtatgct gccaagatca tcaacacaaa gaagctgtca gccagagacc atcagaagct
301 ggagcgtgaa gcccgcatct gccgcctgct gaagcacccc aacatcgtcc gactacatga
361 cagcatctca gaggagggac accactacct gatcttcgac ctggtcactg gtggggaact
421 gtttgaagat atcgtggccc gggagtatta cagtgaggcg gatgccagtc actgtatcca
481 gcagatcctg gaggctgtgc tgcactgcca ccagatgggg gtggtgcacc gggacctgaa
541 gcctgagaat ctgttgctgg cctccaagct caagggtgcc gcagtgaagc tggcagactt
601 tggcctggcc atagaggtgg agggggagca gcaggcatgg tttgggtttg cagggactcc
661 tggatatctc tccccagaag tgctgcggaa ggacccgtac gggaagcctg tggacctgtg
721 ggcttgtggg gtcatcctgt acatcctgct ggttgggtac cccccgttct gggatgagga
781 ccagcaccgc ctgtacaagc agatcaaagc cggcgcctat gatttcccat cgccggaatg
841 ggacactgtc accccggaag ccaaggatct gatcaataag atgctgacca ttaacccatc
901 caaacgcatc acagctgccg aagcccttaa gcacccctgg atctcgcacc gctccaccgt
961 ggcatcctgc atgcacagac aggagaccgt ggactgcctg aagaagttca atgccaggag
1021 gaaactgaag ggagccattc tcaccacgat gctggccacc aggaacttct ccggagggaa
1081 gagtggggga aacaagaaga gcgatggtgt gaaggaatcc tcagagagca ccaacaccac
1141 catcgaggat gaagacacca aagtgcggaa acaggaaatt ataaaagtga cagagcagct
1201 gattgaagcc ataagcaatg gagattttga gtcctacacg aagatgtgcg accctggcat
1261 gacagccttc gaacctgagg ccctggggaa cctggttgag ggcctggact tccatcgatt
1321 ctattttgaa aacctgtggt cccggaacag caagcccgtg cacaccacca tcctgaatcc
1381 ccacatccac ctgatgggcg acgagtcagc ctgcatcgcc tacatccgca tcacgcagta
1441 cctggacgct ggcggcatcc cacgcaccgc ccagtcggag gagacccgtg tctggcaccg
1501 ccgggacggc aaatggcaga tcgtccactt ccacagatct ggggcgccct ccgtcctgcc
1561 ccactgaggg accaggctgg ggtcgctgcg ttgctgtgcc gcagagatcc actctgtccg
1621 tggagtggag ctgctggttc tcccaggtgg attttgctgg aattctccca tgtcatcacc
1681 ccaccacggt cacttctgta cctgcatcaa gaaaacctgc ttgttcacaa aagtcatcgc
1741 aacttcagag cgaacggcca catctcccca cctctcaccc ccaccctctc ccctgccagg
1801 ctggggcttc ctcaggcatg ggtgtccaca gcactggccc cctctcccca gcctcagctg
1861 ctgtccgcct gatctgtctt gggctgtagg ctagaatgcc cgggctgtgt gcccaccagg
1921 ggctggggag aaggaggggt ggcatgatga ggaaggcagc atccgtccgt ccctctccaa
1981 gacctctcct cttccagtgt ccacggggaa gggcggatga cactcccttc cccctaagcc
2041 aaccgcactg aaggagtggg gagaagagca tacgccagga gcctcatgcc tcaaagtgct
2101 cccctaagtc ttcttcctcc tgtgctgacc tcagggtggt ctgacccttc cctcggtgtg
2161 ggggatgtgg ccctctcagg tgcccctact tgctttctgc ttccttctgg tgaagtccac
2221 ctccaacatt aacctgccca ccccaccccc gtcatccctg gagaattcca gctttgtcgt
2281 atctcagaga gggaatctaa ttgtttttgg ggggcaaaag aaagcaacgt ttaggtatca
2341 cttctacttg gaccgcatgc ctttttatag ccaaatttct gtgtatttcg taaatggatt
2401 tcgcgttaat ggatatttat gtaataacta gacttctcag attattgtga gaagggtcag
2461 gttggaaggg gtgtaggaag aggggtgagg ggtagttttt ttctgttcta gttttttttt
2521 tttttttttt ttttttgtca tctctgaggt ggaccttgtc acctgtggtt attggggcca
2581 aggcggactg agctccgggg agaagggcct ctctgccatt tcggtcccaa ggtgagctga
2641 cacaggcgtt ccttttggga ctgtggaagc atcagatgcc agcactgact caggaacagc
2701 aagtcagggc agagaggagg agggaggctg tcaggatgga aatacctgga cttttctttg
2761 cttccctcgc aaactggggt cttctctacc gaacttccaa ggatttcatc tcacaatatc
2821 tgtgtgccgc ccccagcacc ccccacccac ctctgggggg cccgtgagcg tgtgtcttca
2881 ttgcctctct ccccttggcg tctgatgacc acagcaaagc actgggaatt tctactcttc
2941 atgcctcatc ctgcagcctc gggttcgcat tctctctttc ttttcctctt tccctctttc
3001 cctgggattg actctgagtg gaataccttg gcacatccac taggatctac tgtctgcact
3061 gttttctttg catgacttta tacgcagtaa gtatgttgaa aacaaacaaa aagaagaaaa
3121 cactcaacaa aaccaatcta catgttttgg actaaaaaaa aaaatagagg ttgtattctc
3181 agtgtccgac tcggaattat gttgctgcct ctctgtgctt ttggcctctg tgtggccgtg
3241 ttttgccagc atgagatact gtcccctctg gaggatttta ggggaggaag agccacgtcc
3301 ccagggattg gaggaggctc cggtaccctc gaccctcctg ggtgttggtt ggagcagaac
3361 tggtgaggat gtttgatccg agattttctg agctctcccc gatcaccagc tgtctgctgg
3421 gttcttttct caagtcctgc tgcccaggcc caggtgagac aggcaacgcc aggtctgcag
3481 gccaggagag atgctgccca ggcctcctgg tttccaagct ggtccatcac tggcctctgt
3541 ccttggcaga gaccttgctg cccaggccca ggggcaggct cttggcctgc cccaggccca
3601 gagggcttcc cagtaaggcc cagtgatccc attatcccag gggcaaaacc acctgtcccc
3661 ttttgagctg ccagttccct acagccatcc ccagtcaagg gtgagggtgt ggccttcacc
3721 aggggctgct gtaattaccg agcaaggtct gagctcttct tcagcctaag ttccctcatt
3781 ggttaaaagg gttctttgtt cccatccagc cgatgaagga gcaaacgtct ggctatgtga
3841 agcctaattt acctgcagga actggcaggg atagtcactg gctggactcc tgtttacttc
3901 tagacctggt caggctccat cccctccccc acctgcccct gattcccctc gtcggtgcct
3961 gtcaactgct tttcagcagt ggactgcagg ggaaagagca gtgatttggg gtgagtaggc
4021 ttcaattccc agctctgacc agacttgctg tgtgaccttg ggcaagttcc tttccctctt
4081 tggagcttgg tttccctgcc agaggaaact gagctggagg agcctgaggt cctgcctttc
4141 attggctgac acacctcctg tccactgtgt cactctccaa gtgccagaga agtggaggca
4201 gatcgctacc ccaggctgag atggccccca ctgtgaaggc cacgcctgtg ggtgggcagc
4261 cacctggtgc caccacaggg caccagggat gatcctgatg cggcaggcag gggagactca
4321 cagaaaaatc tgcccagagc ctaccctcac cagacaaact ctgtgctcct ccaaaacatc
4381 ctttagatgc aaaataataa taaataataa taataaataa ataaaaatcc aaacccaagt
4441 caaaaccttg gctccagcat gaaaacacgt ttacaggaaa gtgttctcct gggtttgtgc
4501 ccaccatggt gcgaatcctg acccaaggcc tcctgtctcc cttcaaaggg agaccctttt
4561 gggggatgag tttgccagac tccccgtgct ggtttctttg ttactatttg tttggggttt
4621 tgttttagtt cttttttttt tttcttttct tttttaaaaa tatgtggctg tgaacttgaa
4681 tgaacactgc tcaaactttc tgctattgag gggggcgggt gggatgggaa gaaggggcat
4741 ttgttttatt cttggtgttt tcagtgcaat aaatagctac aaacttctgt gcaaaaaaaa
4801 aaaaaaa
//