LOCUS BC040430 1954 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens cytochrome P450, family 27, subfamily A, polypeptide
1, mRNA (cDNA clone MGC:48721 IMAGE:5760376), complete cds.
ACCESSION BC040430
VERSION BC040430.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1954)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1954)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-NOV-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 84 Row: m Column: 1
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 13904863.
FEATURES Location/Qualifiers
source 1..1954
/db_xref="H-InvDB:HIT000096160"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:48721 IMAGE:5760376"
/tissue_type="Colon, Kidney, Stomach, adult, whole pooled"
/clone_lib="NIH_MGC_116"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1954
/gene="CYP27A1"
/gene_synonym="CP27"
/gene_synonym="CTX"
/db_xref="GeneID:1593"
/db_xref="HGNC:HGNC:2605"
/db_xref="MIM:606530"
CDS 15..1610
/gene="CYP27A1"
/gene_synonym="CP27"
/gene_synonym="CTX"
/codon_start=1
/product="cytochrome P450, family 27, subfamily A,
polypeptide 1"
/protein_id="AAH40430.1"
/db_xref="GeneID:1593"
/db_xref="HGNC:HGNC:2605"
/db_xref="MIM:606530"
/translation="MAALGCARLRWALRGAGRGLCPHGARAKAAIPAALPSDKATGAP
GAGPGVRRRQRSLEEIPRLGQLRFFFQLFVQGYALQLHQLQVLYKAKYGPMWMSYLGP
QMHVNLASAPLLEQVMRQEGKYPVRNDMELWKEHRDQHDLTYGPFTTEGHHWYQLRQA
LNQRLLKPAEAALYTDAFNEVIDDFMTRLDQLRAESASGNQVSDMAQLFYYFALEAIC
YILFEKRIGCLQRSIPEDTVTFVRSIGLMFQNSLYATFLPKWTRPVLPFWKRYLDGWN
AIFSFGKKLIDEKLEDMEAQLQAAGPDGIQVSGYLHFLLASGQLSPREAMGSLPELLM
AGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHKDFAHMPLLKAVLKE
TLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEPESFQPHRWL
RNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLAPETGEL
KSVARIVLVPNKKVGLQFLQRQC"
BASE COUNT 467 a 546 c 544 g 397 t
ORIGIN
1 cgcgagcaca acccatggct gcgctgggct gcgcgaggct gaggtgggcg ctgcgagggg
61 ccggccgtgg cctctgcccc cacggggcca gagccaaggc cgcgatccct gccgccctcc
121 cctcggacaa ggccaccgga gctcccggag ccgggcctgg tgtccggcgg cggcaacgga
181 gcttagagga gattccacgt ctaggacagc tgcgcttctt ctttcagctg ttcgttcaag
241 gctatgccct gcaactgcac cagttacagg tgctttacaa ggccaagtac ggtccaatgt
301 ggatgtccta cttagggcct cagatgcacg tgaacctggc cagtgccccg ctcttggagc
361 aagtgatgcg gcaagagggc aagtacccag tacggaacga catggagcta tggaaggagc
421 accgggacca gcacgacctg acctatgggc cgttcaccac ggaaggacac cactggtacc
481 agctgcgcca ggctctgaac cagcggttgc tgaagccagc ggaagcagcg ctctatacgg
541 atgctttcaa tgaggtgatt gatgacttta tgactcgact ggaccagctg cgggcagaga
601 gtgcttcggg gaaccaggtg tcggacatgg ctcaactctt ctactacttt gccttggaag
661 ctatttgcta catcctgttc gagaaacgca ttggctgcct gcagcgatcc atccccgagg
721 acaccgtgac cttcgtcaga tccatcgggt taatgttcca gaactcactc tatgccacct
781 tcctccccaa gtggactcgc cccgtgctgc ctttctggaa gcgatacctg gatggttgga
841 atgccatctt ttcctttggg aagaagctga ttgatgagaa gctcgaagat atggaggccc
901 aactgcaggc agcagggcca gatggcatcc aggtgtctgg ctacctgcac ttcttactgg
961 ccagtggaca gctcagtcct cgggaggcca tgggcagcct gcctgagctg ctcatggctg
1021 gagtggacac gacatccaac acgctgacat gggccctgta ccacctctca aaggaccctg
1081 agatccagga ggccttgcac gaggaagtgg tgggtgtggt gccagccggg caagtgcccc
1141 agcacaagga ctttgcccac atgccgttgc tcaaagctgt gcttaaggag actctgcgtc
1201 tctaccctgt ggtccccaca aactcccgga tcatagaaaa ggaaattgaa gttgatggct
1261 tcctcttccc caagaacacc cagtttgtgt tctgccacta tgtggtgtcc cgggacccca
1321 ctgccttctc tgagcctgaa agcttccagc cccaccgctg gctgagaaac agccagcctg
1381 ctacccccag gatccagcac ccatttggct ctgtgccctt tggctatggg gtccgggcct
1441 gcctgggccg caggattgca gagctggaga tgcagctact cctcgcaagg ctgatccaga
1501 agtacaaggt ggtcctggcc ccggagacgg gggagttgaa gagtgtggcc cgcattgtcc
1561 tggttcccaa taagaaagtg ggcctgcagt tcctgcagag acagtgctga gctgagtctc
1621 cgccttgctg gggcttgtcc tagaggctcc agctctggca cagtggttcc tggctgctgc
1681 catgtctcag atgaggaggg agagaaggag gccgccagac tcgagaggtg ggaggaactc
1741 cttgcacaca ccctgagctt ttgccacttc tatcattttt gagcaactcc ctctcagcta
1801 aaaggccacc cctttatcgc attgctgtcc ttgggtagaa tataaaataa agggactttt
1861 atttcttatt ggaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1921 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa
//