LOCUS BC039841 2573 bp mRNA linear HUM 11-AUG-2006
DEFINITION Homo sapiens ferrochelatase (protoporphyria), mRNA (cDNA clone
MGC:48846 IMAGE:6042757), complete cds.
ACCESSION BC039841
VERSION BC039841.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2573)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2573)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-NOV-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 84 Row: n Column: 10
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 60499020.
FEATURES Location/Qualifiers
source 1..2573
/db_xref="H-InvDB:HIT000052266"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:48846 IMAGE:6042757"
/tissue_type="Testis, embryonal carcinoma"
/clone_lib="NIH_MGC_92"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2573
/gene="FECH"
/gene_synonym="EPP"
/gene_synonym="FCE"
/db_xref="GeneID:2235"
/db_xref="HGNC:HGNC:3647"
/db_xref="MIM:177000"
CDS 85..1356
/gene="FECH"
/gene_synonym="EPP"
/gene_synonym="FCE"
/codon_start=1
/product="ferrochelatase (protoporphyria)"
/protein_id="AAH39841.2"
/db_xref="GeneID:2235"
/db_xref="HGNC:HGNC:3647"
/db_xref="MIM:177000"
/translation="MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAA
VTTETAQHAQGAKPQVQPQKRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLP
IQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYY
IGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPT
MKWSTIDRWPTHHLLIQCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPY
PQEVSATVQKVMERLEYCNPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVP
IAFTSDHIETLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSN
ELCSKQLTLSCPLCVNPVCRETKSFFTSQQL"
BASE COUNT 689 a 588 c 610 g 686 t
ORIGIN
1 ctacccggct cggccactgc tgggcggaca cctgggcgcg ccgccgcggg aggagcccgg
61 actcgggccg aggctgccca ggcaatgcgt tcactcggcg caaacatggc tgcggccctg
121 cgcgccgcgg gcgtcctgct ccgcgatccg ctggcatcca gcagctggag ggtctgtcag
181 ccatggaggt ggaagtcagg tgcagctgca gcggccgtca ccacagaaac agcccagcat
241 gcccagggtg caaaacctca agttcaaccg cagaagagga agccgaaaac tggaatatta
301 atgctaaaca tgggaggccc tgaaactctt ggagatgttc acgacttcct tctgagactc
361 ttcttggacc gagacctcat gacacttcct attcagaata agctggcacc attcatcgcc
421 aaacgccgaa cccccaagat tcaagagcag taccgcagga ttggaggcgg atcccccatc
481 aagatatgga cttccaagca gggagagggc atggtgaagc tgctggatga attgtccccc
541 aacacagccc ctcacaaata ctatattgga tttcggtacg tccatccttt aacagaagaa
601 gcaattgaag agatggagag agatggccta gaaagggcta ttgctttcac acagtatcca
661 cagtacagct gctccaccac aggcagcagc ttaaatgcca tttacagata ctataatcaa
721 gtgggacgga agcccacgat gaagtggagc actattgaca ggtggcccac acatcacctc
781 ctcatccagt gctttgcaga tcatattcta aaggaactgg accattttcc acttgagaag
841 agaagcgagg tggtcattct gttttctgct cactcactgc ccatgtctgt ggtcaacaga
901 ggcgacccat atcctcagga ggtaagcgcc actgtccaaa aagtcatgga aaggctggag
961 tactgcaacc cctaccgact ggtgtggcaa tccaaggttg gtccaatgcc ctggttgggt
1021 cctcaaacag acgaatctat caaagggctt tgtgagaggg ggaggaagaa tatcctcttg
1081 gttccgatag catttaccag tgaccatatt gaaacgctgt atgagctgga catcgagtac
1141 tctcaagttt tagccaagga gtgtggagtt gaaaacatca gaagagctga gtctcttaat
1201 ggaaatccat tgttctctaa ggccctggcc gacttggtgc attcacacat ccagtcaaac
1261 gagctgtgtt ccaagcagct gaccctgagc tgtccgctct gtgtcaatcc tgtctgcagg
1321 gagactaaat ccttcttcac cagccagcag ctgtgacccc cgccggtgga ccccgtggcg
1381 ttaggcaaat gcccaacctc cagatacctc cgatgtggag agggtgttat ttagagatca
1441 aggaaggaag tcatccttcc ttgatatata tacagccttt gggtacaaat tgtgtggttt
1501 cttgaggatt ggactcttga tggatttcta tttttatata actatacagt aagcatttgt
1561 attttctctc tctaggtata agttactagt ttggaatgtc catcaggacc tttaataaat
1621 gagttaaaaa tttgtcttat gagacacacc tatttaagta cagattttgg ctttattgcc
1681 caaaaccctc ctgaaagggt acggagagtc ccctctgtgg gctggcagtg tgaatgagat
1741 ctgtttagtc tcgtgcatat agttgctgtt ttttaaatga acacagttga gtatttgaag
1801 tgaatttgaa aaagaaatgt tacttaatct ttccctaagc ccatgggtta cagaatgcta
1861 gggaggcaat ttggttacct gcaatggctg cttttgccag cgaggccacc attcattggt
1921 catcttggta tttgtgtgtg aatctcactt tcctcaatgt aaaaaggaat caagtatgga
1981 tttcagaggt gctcttagat tccccataca cccaagggta ataaacgtgt acaagtacag
2041 tgttcatgat acgtgccttg gtgggagtcc gtggtgccac agggaagggg ctcccactgc
2101 ttctggtctc cagggacagt gctgctggaa aggctagtga tgagcttcac cctggagctc
2161 ctcccgggac cttgcaagcc tctccatcca gcatcttctc tatcttagtt gaatgccttc
2221 tttctgaaca tttgttttaa gaattatttt ataaagtcaa caatactttg cttgaattct
2281 ttcttaattt acgatttttt attataaaaa tgtatagtga tacaatggga catgtgaaga
2341 atacagaaaa gtaaccactt taatgcaata actgttatca taatattgta tttcgtggta
2401 gtcctttcct gtagatattt ttaatgccat ttaatgccat tgtcaccttg gatttatgag
2461 tgaaaagtgt ttctaaaaat atagaaataa tgtcagatca gagtctgatc ttctatgttt
2521 gtatttaaat ggattaaaag atccccggtg gttccatgaa aaaaaaaaaa aaa
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