LOCUS BC039731 2791 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens preferentially expressed antigen in melanoma, mRNA
(cDNA clone MGC:47530 IMAGE:5744328), complete cds.
ACCESSION BC039731
VERSION BC039731.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2791)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2791)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-NOV-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 82 Row: j Column: 22
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 46249365.
FEATURES Location/Qualifiers
source 1..2791
/db_xref="H-InvDB:HIT000052242"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:47530 IMAGE:5744328"
/tissue_type="Brain, adult medulla"
/clone_lib="NIH_MGC_119"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2791
/gene="PRAME"
/gene_synonym="OIP4"
/db_xref="GeneID:23532"
/db_xref="HGNC:HGNC:9336"
/db_xref="MIM:606021"
CDS 830..2359
/gene="PRAME"
/gene_synonym="OIP4"
/codon_start=1
/product="preferentially expressed antigen in melanoma"
/protein_id="AAH39731.1"
/db_xref="GeneID:23532"
/db_xref="HGNC:HGNC:9336"
/db_xref="MIM:606021"
/translation="MERRRLRGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAA
LELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLD
GLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRK
VDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAM
PMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYI
SPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRL
SEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATLQDLVFDECGITD
DQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVLYPVPLESYED
IHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEPILCPCFMP
N"
BASE COUNT 690 a 698 c 751 g 652 t
ORIGIN
1 gccagaagcc gggcctgcag cgcctcagca ccgctccggg acaccccacc cgcttcccag
61 gcgtgacctg tcaacagcaa cttcgcggtg tggtgaactc tctgaggaaa aacgtaagtt
121 cgagccctga ttcctccgct tccccgcagg gtgaccttgg gcttgtgccc ccggcaccac
181 ccctgtcccg ggtccctgtt ttctctctgg aaatgggttg aagaccaaag aaaataatgt
241 gcgccacttg ggtcaccccg ggccgcctgc cccggaaaat tggccccagt tgaggagttg
301 tggctgtaag gatgccttga accgaggcgg cggtgctcgt ggttggagct ctccagggtg
361 ggtgcgcatt tgtaatgcgg tggatgctct gggactcggc ccctctgaag gtgcttgggg
421 gttggggacg gcccaggcag cagtggcgta ggcgtcctag gaaggcggga gcagaggcag
481 aaatgtcgct gcaagaccgt agtcagggtc cttgaccaca ggggtcactt gtgaccaacc
541 acatggtctg ttgttcctcc tgccccctgg ttcagcccag gaaacactgg tgctcaggtt
601 tggagccaga gatttgcact gaaagggcgg gattgagtcg ccagttgtca gtttcctcag
661 cagtattcgc ggaggttttc acaggaggcc gttgcttcgt aaatattata catgtatctt
721 tctttttgga gcattttgat tattactctc agacgtgcgt ggcaacaagt gactgagacc
781 tagaaatcca agcgttggag gtcctgaggc cagcctaagt cgcttcaaaa tggaacgaag
841 gcgtttgcgg ggttccattc agagccgata catcagcatg agtgtgtgga caagcccacg
901 gagacttgtg gagctggcag ggcagagcct gctgaaggat gaggccctgg ccattgccgc
961 cctggagttg ctgcccaggg agctcttccc gccactcttc atggcagcct ttgacgggag
1021 acacagccag accctgaagg caatggtgca ggcctggccc ttcacctgcc tccctctggg
1081 agtgctgatg aagggacaac atcttcacct ggagaccttc aaagctgtgc ttgatggact
1141 tgatgtgctc cttgcccagg aggttcgccc caggaggtgg aaacttcaag tgctggattt
1201 acggaagaac tctcatcagg acttctggac tgtatggtct ggaaacaggg ccagtctgta
1261 ctcatttcca gagccagaag cagctcagcc catgacaaag aagcgaaaag tagatggttt
1321 gagcacagag gcagagcagc ccttcattcc agtagaggtg ctcgtagacc tgttcctcaa
1381 ggaaggtgcc tgtgatgaat tgttctccta cctcattgag aaagtgaagc gaaagaaaaa
1441 tgtactacgc ctgtgctgta agaagctgaa gatttttgca atgcccatgc aggatatcaa
1501 gatgatcctg aaaatggtgc agctggactc tattgaagat ttggaagtga cttgtacctg
1561 gaagctaccc accttggcga aattttctcc ttacctgggc cagatgatta atctgcgtag
1621 actcctcctc tcccacatcc atgcatcttc ctacatttcc ccggagaagg aagagcagta
1681 tatcgcccag ttcacctctc agttcctcag tctgcagtgc ctgcaggctc tctatgtgga
1741 ctctttattt ttccttagag gccgcctgga tcagttgctc aggcacgtga tgaacccctt
1801 ggaaaccctc tcaataacta actgccggct ttcggaaggg gatgtgatgc atctgtccca
1861 gagtcccagc gtcagtcagc taagtgtcct gagtctaagt ggggtcatgc tgaccgatgt
1921 aagtcccgag cccctccaag ctctgctgga gagagcctct gccaccctcc aggacctggt
1981 ctttgatgag tgtgggatca cggatgatca gctccttgcc ctcctgcctt ccctgagcca
2041 ctgctcccag cttacaacct taagcttcta cgggaattcc atctccatat ctgccttgca
2101 gagtctcctg cagcacctca tcgggctgag caatctgacc cacgtgctgt atcctgtccc
2161 cctggagagt tatgaggaca tccatggtac cctccacctg gagaggcttg cctatctgca
2221 tgccaggctc agggagttgc tgtgtgagtt ggggcggccc agcatggtct ggcttagtgc
2281 caacccctgt cctcactgtg gggacagaac cttctatgac ccggagccca tcctgtgccc
2341 ctgtttcatg cctaactagc tgggtgcaca tatcaaatgc ttcattctgc atacttggac
2401 actaaagcca ggatgtgcat gcatcttgaa gcaacaaagc agccacagtt tcagacaaat
2461 gttcagtgtg agtgaggaaa acatgttcag tgaggaaaaa acattcagac aaatgttcag
2521 tgaggaaaaa aaggggaagt tgggggtagg cagatgttga cttgaggagt taatgtgctc
2581 tttggggaga tacatcttat agagttagaa atagaatctg aatttctaaa gggagattct
2641 ggcttgggaa gtacatgtag gagttaatcc ctgtgtagac tgttgtaaag aaactgttga
2701 aaataaagag aagcaatgtg aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2761 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a
//