LOCUS BC039082 1732 bp mRNA linear HUM 20-DEC-2004
DEFINITION Homo sapiens transmembrane protease, serine 6, mRNA (cDNA clone
MGC:35027 IMAGE:5164881), complete cds.
ACCESSION BC039082
VERSION BC039082.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1732)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1732)
AUTHORS Director MGC Project.
TITLE Direct Submission
JOURNAL Submitted (01-NOV-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 52 Row: k Column: 12
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 23957701.
FEATURES Location/Qualifiers
source 1..1732
/db_xref="H-InvDB:HIT000052136"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:35027 IMAGE:5164881"
/tissue_type="Brain, adult medulla"
/clone_lib="NIH_MGC_119"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1732
/gene="TMPRSS6"
/db_xref="GeneID:164656"
CDS 118..1503
/gene="TMPRSS6"
/codon_start=1
/product="TMPRSS6 protein"
/protein_id="AAH39082.1"
/db_xref="GeneID:164656"
/translation="MLLLFHSKRMPVAEAPQVAGGQGDGGDGEEAEPEGMFKACEDSK
RKARGYLRLVPLFVLLALLVLASAGVLLWYFLGYKAEVMVSQVYSGSLRVLNRHFSQD
LTRRESSAFRSETAKAQKMLKELITSTRLGTYYNSSSVYSFGEGPLTCFFWFILQIPE
HRRLMLSPEVVQALLVEELLSTVNSSAAVPYRAEYEVDPEGLVILEASVKDIAALNST
LGCYRYSYVGQGQVLRLKGPDHLASSCLWHLQGPKDLMLKLRLEWTLAECRDRLAMYD
VAGPLEKRLITSVYGCSRQEPVVEVLASGAIMAVVWKKGLHSYYDPFVLSVQPVVFQA
CEVNLTLDNRLDSQGVLSTPYFPSYYSPQTHCSWHLTVPSLDYGLALWFDAYALRRQK
YDLPCTQGQWTIQNRRYHFLSSLWLPFLPPPPSLPSSTVTPSLEAQVPNLRGAARGAS
RGWGWCQACCP"
BASE COUNT 340 a 555 c 481 g 356 t
ORIGIN
1 gttcttgagc cagacccagt ccagctctgg tgcctgccct ctggtgcgag ctgacctgag
61 atgcacttcc ctcctctgtg agctgtctcg gcacccactt gcagtcactg ccgcctgatg
121 ttgttactct tccactccaa aaggatgccc gtggccgagg ccccccaggt ggctggcggg
181 cagggggacg gaggtgatgg cgaggaagcg gagccagagg ggatgttcaa ggcctgtgag
241 gactccaaga gaaaagcccg gggctacctc cgcctggtgc ccctgtttgt gctgctggcc
301 ctgctcgtgc tggcttcggc gggggtgcta ctctggtatt tcctagggta caaggcggag
361 gtgatggtca gccaggtgta ctcaggcagt ctgcgtgtac tcaatcgcca cttctcccag
421 gatcttaccc gccgggaatc tagtgccttc cgcagtgaaa ccgccaaagc ccagaagatg
481 ctcaaggagc tcatcaccag cacccgcctg ggaacttact acaactccag ctccgtctat
541 tcctttgggg agggacccct cacctgcttc ttctggttca ttctccaaat ccccgagcac
601 cgccggctga tgctgagccc cgaggtggtg caggcactgc tggtggagga gctgctgtcc
661 acagtcaaca gctcggctgc cgtcccctac agggccgagt acgaagtgga ccccgagggc
721 ctagtgatcc tggaagccag tgtgaaagac atagctgcat tgaattccac gctgggttgt
781 taccgctaca gctacgtggg ccagggccag gtcctccggc tgaaggggcc tgaccacctg
841 gcctccagct gcctgtggca cctgcagggc cccaaggacc tcatgctcaa actccggctg
901 gagtggacgc tggcagagtg ccgggaccga ctggccatgt atgacgtggc cgggcccctg
961 gagaagaggc tcatcacctc ggtgtacggc tgcagccgcc aggagcccgt ggtggaggtt
1021 ctggcgtcgg gggccatcat ggcggtcgtc tggaagaagg gcctgcacag ctactacgac
1081 cccttcgtgc tctccgtgca gccggtggtc ttccaggcct gtgaagtgaa cctgacgctg
1141 gacaacaggc tcgactccca gggcgtcctc agcaccccgt acttccccag ctactactcg
1201 ccccaaaccc actgctcctg gcacctcacg gtgccctctc tggactacgg cttggccctc
1261 tggtttgatg cctatgcact gaggaggcag aagtatgatt tgccgtgcac ccagggccag
1321 tggacgatcc agaacaggag gtaccacttc ctctcctccc tctggcttcc tttcctccct
1381 ccccctccct ctcttccctc ctcaacagtg accccctcat tggaagccca agtccccaat
1441 ctcagagggg cagcaagggg agcgagcaga ggctggggct ggtgtcaggc ctgctgccct
1501 tgaccttgtc ctcgtcccaa cctccgccct ggccccggct tcccctctgg ctaccccaga
1561 ggtctcagac acgtttggtc atcagacacc ttggatgttt attctaatta cagcaaaatt
1621 gtctcatctt cttgggtgct gtaaccccct ctggcaccct caatccttca ataaaatgtt
1681 tccagagcca aaggaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa
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