LOCUS BC038234 2635 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens phosphodiesterase 4A, cAMP-specific (phosphodiesterase
E2 dunce homolog, Drosophila), mRNA (cDNA clone MGC:46146
IMAGE:5732341), complete cds.
ACCESSION BC038234
VERSION BC038234.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2635)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2635)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (30-SEP-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Invitrogen
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 79 Row: j Column: 23
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 5453861.
FEATURES Location/Qualifiers
source 1..2635
/db_xref="H-InvDB:HIT000052006"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:46146 IMAGE:5732341"
/tissue_type="Brain, hippocampus"
/clone_lib="NIH_MGC_124"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2635
/gene="PDE4A"
/gene_synonym="PDE4"
/db_xref="GeneID:5141"
/db_xref="HGNC:HGNC:8780"
/db_xref="MIM:600126"
CDS 326..2269
/gene="PDE4A"
/gene_synonym="PDE4"
/codon_start=1
/product="phosphodiesterase 4A, cAMP-specific
(phosphodiesterase E2 dunce homolog, Drosophila)"
/protein_id="AAH38234.1"
/db_xref="GeneID:5141"
/db_xref="HGNC:HGNC:8780"
/db_xref="MIM:600126"
/translation="MPLVDFFCETCSKPWLVGWWDQFKRMLNRELTHLSEMSRSGNQV
SEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPPPPVPHLQPMSQITGLKKL
MHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIF
QERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAV
FTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQ
EDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMC
DKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAIRQSPSP
PPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALD
ATIAWEASPAQESLEVMAQEASLEAELEAVYLTQQAQSTGSAPVAPDEFSSREEFVVA
VSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA
GTFGEDTSALPAPGGGGSGGDPT"
BASE COUNT 628 a 818 c 705 g 484 t
ORIGIN
1 cgggtgcaca cacagagctc cgcagcctcc tcctgggacc cttgccctgc ccccctccca
61 tgggcacgga ccccccaccg cctccaccca ctgccgcggg ggggcccgtt ggggcccagg
121 gctggcgggc catgtaacca gggctgctgc tgggagcgcg gaggggaagg gagcccccag
181 ccctgctggg ccggcccagg cccctccgcg gctccccctt ccactaccca cctgcccggc
241 accccctccc cagtggttgt taaccccggg actccccaag cccagcctct gtgtgcagca
301 gccccaggcg ggctaagtct ccaagatgcc cttggtggat ttcttctgcg agacctgctc
361 taagccttgg ctggtgggct ggtgggacca gttcaaaagg atgttgaacc gtgagctcac
421 acacctgtca gaaatgagca ggtccggaaa ccaggtctca gagtacattt ccacaacatt
481 cctggacaaa cagaatgaag tggagatccc atcacccacg atgaaggaac gagaaaaaca
541 gcaagcgccg cgaccaagac cctcccagcc gcccccgccc cctgtaccac acttacagcc
601 catgtcccaa atcacagggt tgaaaaagtt gatgcatagt aacagcctga acaactctaa
661 cattccccga tttggggtga agaccgatca agaagagctc ctggcccaag aactggagaa
721 cctgaacaag tggggcctga acatcttttg cgtgtcggat tacgctggag gccgctcact
781 cacctgcatc atgtacatga tattccagga gcgggacctg ctgaagaaat tccgcatccc
841 tgtggacacg atggtgacat acatgctgac gctggaggat cactaccacg ctgacgtggc
901 ctaccataac agcctgcacg cagctgacgt gctgcagtcc acccacgtac tgctggccac
961 gcctgcacta gatgcagtgt tcacggacct ggagattctc gccgccctct tcgcggctgc
1021 catccacgat gtggatcacc ctggggtctc caaccagttc ctcatcaaca ccaattcgga
1081 gctggcgctc atgtacaacg atgagtcggt gctcgagaat caccacctgg ccgtgggctt
1141 caagctgctg caggaggaca actgcgacat cttccagaac ctcagcaagc gccagcggca
1201 gagcctacgc aagatggtca tcgacatggt gctggccacg gacatgtcca agcacatgac
1261 cctcctggct gacctgaaga ccatggtgga gaccaagaaa gtgaccagct caggggtcct
1321 cctgctagat aactactccg accgcatcca ggtcctccgg aacatggtgc actgtgccga
1381 cctcagcaac cccaccaagc cgctggagct gtaccgccag tggacagacc gcatcatggc
1441 cgagttcttc cagcagggtg accgagagcg cgagcgtggc atggaaatca gccccatgtg
1501 tgacaagcac actgcctccg tggagaagtc tcaggtgggt tttattgact acattgtgca
1561 cccattgtgg gagacctggg cggaccttgt ccacccagat gcccaggaga tcttggacac
1621 tttggaggac aaccgggact ggtactacag cgccatccgg cagagcccat ctccgccacc
1681 cgaggaggag tcaagggggc caggccaccc acccctgcct gacaagttcc agtttgagct
1741 gacgctggag gaggaagagg aggaagaaat atcaatggcc cagataccgt gcacagccca
1801 agaggcattg actgcgcagg gattgtcagg agtcgaggaa gctctggatg caaccatagc
1861 ctgggaggca tccccggccc aggagtcgtt ggaagttatg gcacaggaag catccctgga
1921 ggccgagctg gaggcagtgt atttgacaca gcaggcacag tccacaggca gtgcacctgt
1981 ggctccggat gagttctcgt cccgggagga attcgtggtt gctgtaagcc acagcagccc
2041 ctctgccctg gctcttcaaa gcccccttct ccctgcttgg aggaccctgt ctgtttcaga
2101 gcatgccccg ggcctcccgg gcctcccctc cacggcggcc gaggtggagg cccaacgaga
2161 gcaccaggct gccaagaggg cttgcagtgc ctgcgcaggg acatttgggg aggacacatc
2221 cgcactccca gctcctggtg gcggggggtc aggtggagac cctacctgat ccccagacct
2281 ctgtccctgt tcccctccac tcctcccctc actcccctgc tcccccgacc acctcctcct
2341 ctgcctcaaa gactcttgtc ctcttgtccc tcctgagaaa aaagaaaacg aaaagtgggg
2401 tttttttctg ttttcttttt ttcccctttc cccctgcccc cacccacggg gccttttttt
2461 ggaggtgggg gctggggaat gaggggctga ggtcccggaa gggattttat ttttttgaat
2521 tttaattgta acatttttag aaaaagaaca aaaaaagaaa aaaaaaagaa agaaacacaa
2581 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa
//