LOCUS BC037965 2172 bp mRNA linear HUM 24-JAN-2005
DEFINITION Homo sapiens WNK lysine deficient protein kinase 2, mRNA (cDNA
clone IMAGE:5735496), partial cds.
ACCESSION BC037965
VERSION BC037965.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2172)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2172)
AUTHORS Director MGC Project.
TITLE Direct Submission
JOURNAL Submitted (20-SEP-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP/Gazdar
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 79 Row: j Column: 8
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 32455272.
FEATURES Location/Qualifiers
source 1..2172
/db_xref="H-InvDB:HIT000095068"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:5735496"
/tissue_type="Lung, large cell carcinoma"
/clone_lib="NIH_MGC_68"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene <1..2172
/gene="WNK2"
/gene_synonym="NY-CO-43"
/gene_synonym="P/OKcl.13"
/gene_synonym="PRKWNK2"
/gene_synonym="SDCCAG43"
/db_xref="GeneID:65268"
/db_xref="MIM:606249"
CDS <1..1953
/gene="WNK2"
/gene_synonym="NY-CO-43"
/gene_synonym="P/OKcl.13"
/gene_synonym="PRKWNK2"
/gene_synonym="SDCCAG43"
/codon_start=1
/product="WNK2 protein"
/protein_id="AAH37965.1"
/db_xref="GeneID:65268"
/db_xref="MIM:606249"
/translation="PRVRAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEA
VSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHV
VPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALG
SPRKRPEQQDVSSPAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVK
LAVRRAQTASSIEVGVGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAF
LQRPSRAGSLGPETPSRVGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQSLR
EKHLKEISELQSQQKQEIEALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKL
LNPLVRQLKVVASSTGHLADSSRGPPAKDPAQASVGLTADSTGLSGKAVQTQQPCSVR
ASLSSDICSGLASDGGGARGQGWTVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSAL
KRLCLGKEHSSRSSTSSLAPGPEPGPQPALHVQAQVNNSNNKKGTFTDDLHKLVDEWT
SKTVGAAQLKPTLNQLKQTQKLQDMEAQAGWAAPGEARAMTAPRAGVGMPRLPPAPGP
LSTTVIPGAAPTLSVPTPDPESEKPD"
BASE COUNT 486 a 697 c 657 g 332 t
ORIGIN
1 ccacgcgtcc gagctgggac ccctgtggag gtgggcgaca gagacttcac cctggagccc
61 ctgagagggg accagccccg ctcagaggtc tgcggggggg acctggccct gcccccagtg
121 cctaaggagg cggtctcagg gcgtgtccag ctgccccagc ccttggtgga gaagtcagaa
181 ctggccccca ctcgaggggc cgtgatggag cagggcacgt cctcgtcaat gacagcagag
241 tcgtctccca ggagtatgct aggctatgac agagatggaa ggcaggtggc ctcagactcc
301 catgtggtcc ccagcgtccc ccaggatgta cctgcttttg tgagacctgc acgtgtggag
361 cccacagaca gggatggtgg agaagctgga gaaagctcgg cagagccccc gccgagtgac
421 atgggcacag tggggggcca ggctagccac ccccagacac tcggcgctcg agctttgggg
481 tcccctcgga aacgtccaga gcagcaggat gtcagctcac cagccaagac tgtgggccgt
541 ttctcggtgg tcagcactca ggacgagtgg accctggcct ccccccacag cctgagatac
601 tctgccccac ccgacgtcta cctggacgag gccccctcca gccccgacgt gaagctggca
661 gtgcggcggg cgcagacggc ctcctccatc gaggtcggcg tgggcgagcc cgtgtccagc
721 gactctgggg acgagggccc tcgggcgaga cccccggtgc agaagcaggc gtccctgccc
781 gtgagtggca gcgtggctgg cgacttcgtg aagaaggcca ccgccttcct gcagaggcct
841 tctcgggccg gctcgctggg ccccgagaca cccagcaggg tgggcatgaa ggtccccacg
901 atcagcgtga cctccttcca ttcccagtcg tcctacatca gcagcgacaa tgattcggag
961 ctcgaggatg ctgacataaa gaaggagctg cagagtctgc gggagaagca cctgaaggag
1021 atctcggagc tgcagagcca gcagaagcag gagatcgaag ctctgtaccg ccgcctgggc
1081 aagccactgc cccccaacgt gggcttcttc cacacggcac cccccactgg ccgccggaga
1141 aaaaccagca agagcaagct gaaggcaggc aagctgctaa atcccctggt gcggcagctc
1201 aaggtcgtgg cctccagcac aggtcacttg gctgactcca gcagaggccc tcccgctaag
1261 gaccctgccc aagccagtgt ggggctcact gcagacagca cgggcctgag cgggaaggca
1321 gtgcagaccc agcagccctg ctccgtccgg gcctccctgt cttcggacat ctgctccggc
1381 ttagccagtg atggaggcgg agcgcgtggc caaggctgga cggtttacca cccaacgtct
1441 gagagagtga cctataagtc tagtagcaaa cctcgtgctc gattcctcag tggacccgta
1501 tctgtgtcca tctggtctgc cctgaagcgt ctctgcctag gcaaagaaca cagcagtagg
1561 tcctccacca gcagcctggc cccaggccct gagccaggcc cccagcccgc cctgcacgtc
1621 caggcgcagg tgaacaacag caacaacaag aagggtacct tcacggacga cctgcacaag
1681 ctggtggacg agtggacgag caagacggtg ggggccgcgc agctgaagcc cacgctcaac
1741 cagctgaagc agacccagaa gctgcaagac atggaggccc aggcaggctg ggctgcccct
1801 ggcgaggcgc gggctatgac cgcacctcga gcaggagtgg ggatgccacg tctgccccca
1861 gcgcccggcc ctctgtccac cacggtcatt cccggagccg ccccgaccct gtccgtgccc
1921 acaccagatc ctgagagtga gaagcctgac tgaccccgcc tagacgccag gcccacttca
1981 cgccgtctaa gtggagaagt gacggaccct cagggccagc tgctcctcct gtccagttca
2041 cgctgttttg taaccacttt ctaagcattt tttattcaca attggaaaca caaatgtaat
2101 gcaagaataa aaaatatttt ggggcaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2161 aaaaaaaaaa aa
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