LOCUS BC037780 3485 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens glutamate decarboxylase 1 (brain, 67kDa), mRNA (cDNA
clone MGC:41888 IMAGE:5273792), complete cds.
ACCESSION BC037780
VERSION BC037780.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3485)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3485)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (16-SEP-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 25, 2003 this sequence version replaced BC037780.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 75 Row: e Column: 21
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 58331245.
FEATURES Location/Qualifiers
source 1..3485
/db_xref="H-InvDB:HIT000051953"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:41888 IMAGE:5273792"
/tissue_type="Brain, hippocampus"
/clone_lib="NIH_MGC_95"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3485
/gene="GAD1"
/db_xref="GeneID:2571"
/db_xref="HGNC:HGNC:4092"
/db_xref="MIM:605363"
CDS 423..2207
/gene="GAD1"
/codon_start=1
/product="glutamate decarboxylase 1 (brain, 67kDa)"
/protein_id="AAH37780.1"
/db_xref="GeneID:2571"
/db_xref="HGNC:HGNC:4092"
/db_xref="MIM:605363"
/translation="MASSTPSSSATSSNAGADPNTTNLRPTTYDTWCGVAHGCTRKLG
LKICGFLQRTNSLEEKSRLVSAFKERQSSKNLLSCENSDRDARFRRTETDFSNLFARD
LLPAKNGEEQTVQFLLEVVDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSD
HPESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEI
APVFVLMEQITLKKMREIVGWSSKDGDGIFSPGGAISNMYSIMAARYKYFPEVKTKGM
AAVPKLVLFTSEQSRYSIKKAGAALGFGTDNVILIKCNERGEIIPADFEAKILEAKQK
GYVPFYVNATAGTTVYGAFDPIQEIADICEKYNLWLHVDAAWGGGLLMSRKHRHKLNG
IERANSVTWNPHKMMGVLLQCSAILVKEKGILQGCNQMCAGYLFQPDKQYDVSYDTGD
KAIQCGRHVDIFKFWLMWKAKGTVGFENQINKCLELAEYLYAKIKNREEFEMVFNGEP
EHTNVCFWYIPQSLRGVPDSPQRREKLHKVAPKIKALMMESGTTMVGYQPQGDKANFF
RMVISNPAATQSDIDFLIEEIERLGQDL"
BASE COUNT 960 a 801 c 842 g 882 t
ORIGIN
1 ggaaaaccgt gagctggatt tataatcgcc ctataaagct ccagaggcgg tcaggcacct
61 gcagaggagc cccgccgctc cgccgactag ctgcccacgc gagcaacggc ctcgtgattt
121 ccccgccgat ccggtccccg cctacccact ctgcgcccgc ctaccccgga gccgtgcagc
181 cgcctctccg aatctctctc ttctcctggc gctcgcgtgc gagagggaac tagcgagaac
241 gaggaagcag ctggaggtga cgccgggcag attacacctg tcagggccga gccgagcgga
301 tcgctgggcg ctgtgcagag gaaaggcggg agtgcccggc tcgctgtcgc agagcggagc
361 ctgtttctgc gccggaccag tcgaggactc tggacagtag aggccccggg acgaccgagc
421 tgatggcgtc ttcgacccca tcttcgtccg caacctcctc gaacgcggga gcggacccca
481 ataccactaa cctgcgcccc acaacgtacg atacctggtg cggcgtggcc catggatgca
541 ccagaaaact ggggctcaag atctgcggct tcttgcaaag gaccaacagc ctggaagaga
601 agagtcgcct tgtgagtgcc ttcaaggaga ggcaatcctc caagaacctg ctttcctgtg
661 aaaacagcga ccgggatgcc cgcttccggc gcacagagac tgacttctct aatctgtttg
721 ctagagatct gcttccggct aagaacggtg aggagcaaac cgtgcaattc ctcctggaag
781 tggtggacat actcctcaac tatgtccgca agacatttga tcgctccacc aaggtgctgg
841 actttcatca cccacaccag ttgctggaag gcatggaggg cttcaacttg gagctctctg
901 accaccccga gtccctggag cagatcctgg ttgactgcag agacaccttg aagtatgggg
961 ttcgcacagg tcatcctcga tttttcaacc agctctccac tggattggat attattggcc
1021 tagctggaga atggctgaca tcaacggcca ataccaacat gtttacatat gaaattgcac
1081 cagtgtttgt cctcatggaa caaataacac ttaagaagat gagagagata gttggatggt
1141 caagtaaaga tggtgatggg atattttctc ctgggggcgc catatccaac atgtacagca
1201 tcatggctgc tcgctacaag tacttcccgg aagttaagac aaagggcatg gcggctgtgc
1261 ctaaactggt cctcttcacc tcagaacaga gtcgctattc cataaagaaa gctggggctg
1321 cacttggctt tggaactgac aatgtgattt tgataaagtg caatgaaagg ggggaaataa
1381 ttccagctga ttttgaggca aaaattcttg aagccaaaca gaagggatat gttccctttt
1441 atgtcaatgc aactgctggc acgactgttt atggagcttt tgatccgata caagagattg
1501 cagatatatg tgagaaatat aacctttggt tgcatgtcga tgctgcctgg ggaggtgggc
1561 tgctcatgtc caggaagcac cgccataaac tcaacggcat agaaagggcc aactcagtca
1621 cctggaaccc tcacaagatg atgggcgtgc tgttgcagtg ctctgccatt ctcgtcaagg
1681 aaaagggtat actccaagga tgcaaccaga tgtgtgcagg atacctcttc cagccagaca
1741 agcagtatga tgtctcctac gacaccgggg acaaggcaat tcagtgtggc cgccacgtgg
1801 atatcttcaa gttctggctg atgtggaaag caaagggcac agtgggattt gaaaaccaga
1861 tcaacaaatg cctggaactg gctgaatacc tctatgccaa gattaaaaac agagaagaat
1921 ttgagatggt tttcaatggc gagcctgagc acacaaacgt ctgtttttgg tatattccac
1981 aaagcctcag gggtgtgcca gacagccctc aacgacggga aaagctacac aaggtggctc
2041 caaaaatcaa agccctgatg atggagtcag gtacgaccat ggttggctac cagccccaag
2101 gggacaaggc caacttcttc cggatggtca tctccaaccc agccgctacc cagtctgaca
2161 ttgacttcct cattgaggag atagaaagac tgggccagga tctgtaatca tccttcgcag
2221 aacatgagtt tatgggaatg ccttttccct ctggcactcc agaacaaacc tctatatgtt
2281 gctgaaacac acaggccatt tcattgaggg aaaacataat atcttgaaga atattgttaa
2341 aaccttactt aaagcttgtt tgttctagtt agcaggaaat agtgttcttt ttaaaaagtt
2401 gcacattagg aacagagtat atatgtacag ttatacatac ctctctctat atatacatgt
2461 atagtgagtg tggcttagta atagatcacg gcatgtttcc cgctccaaga gaattcactt
2521 taccttcagc agttaccgag gagctaaaca tgctgccaac cagcttgtcc aacaactcca
2581 ggaaaactgt ttttcaaaac gccatgtcct aggggccaag ggaaatgctg ttggtgagaa
2641 tcgacctcac tgtcagcgtt tctccacctg aagtgatgat ggatgagaaa aaacaccacc
2701 aaatgacaag tcacaccctc cccattagta tcctgttagg ggaaaatagt agcagagtca
2761 ttgttacagg tgtactatgg ctgtattttt agagattaat ttgtgtagat tgtgtaaatt
2821 cctgttgtct gaccttggtg gtgggagggg gagactatgt gtcatgattt caatgattgt
2881 ttaattgtag gtcaatgaaa tatttgctta tttatattca gagatgtacc atgttaaaga
2941 ggcgtcttgt attttcttcc catttgtaat gtatcttatt tatatatgaa gtaagttctg
3001 aaaactgttt atggtatttt cgtgcatttg tgagccaaag agaaaagatt aaaattagtg
3061 agatttgtat ttatattaga gtgcccttaa aataatgatt taagcatttt actgtctgta
3121 agagaattct aagattgtac ataaagtcat atatatggaa atcctgttac ttaaatagca
3181 tctgctcttc tcttacgctc tctgtctggc tgtacgtctg gtgttctcaa tgcttttcta
3241 gcaactgttg gataataact agatctcctg taattttgta gtagttgatg accaatctct
3301 gtgactcgct tagctgaaac ctaaggcaac atttccgaag accttctgaa gatctcagat
3361 aaagtgacca ggctcacaac tgtttttgaa gaagggaaat tcacactgtg cgttttagag
3421 tatgcaagaa gaatataaat aaataaaaat attctccatg gagaattcga aaaaaaaaaa
3481 aaaaa
//