LOCUS BC037491 3992 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens ligase IV, DNA, ATP-dependent, mRNA (cDNA clone
MGC:33819 IMAGE:5259632), complete cds.
ACCESSION BC037491
VERSION BC037491.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3992)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3992)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (06-SEP-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 25, 2003 this sequence version replaced BC037491.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 47 Row: e Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 46255051.
FEATURES Location/Qualifiers
source 1..3992
/db_xref="H-InvDB:HIT000051922"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:33819 IMAGE:5259632"
/tissue_type="Brain, hippocampus"
/clone_lib="NIH_MGC_95"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3992
/gene="LIG4"
/db_xref="GeneID:3981"
/db_xref="HGNC:HGNC:6601"
/db_xref="MIM:601837"
CDS 153..2888
/gene="LIG4"
/codon_start=1
/product="ligase IV, DNA, ATP-dependent"
/protein_id="AAH37491.1"
/db_xref="GeneID:3981"
/db_xref="HGNC:HGNC:6601"
/db_xref="MIM:601837"
/translation="MAASQTSQTVASHVPFADLCSTLERIQKSKGRAEKIRHFREFLD
SWRKFHDALHKNHKDVTDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPRD
GKDALKLLNYRTPTGTHGDAGDFAMIAYFVLKPRCLQKGSLTIQQVNDLLDSIASNNS
AKRKDLIKKSLLQLITQSSALEQKWLIRMIIKDLKLGVSQQTIFSVFHNDAAELHNVT
TDLEKVCRQLHDPSVGLSDISITLFSAFKPMLAAIADIEHIEKDMKHQSFYIETKLDG
ERMQMHKDGDVYKYFSRNGYNYTDQFGASPTEGSLTPFIHNAFKADIQICILDGEMMA
YNPNTQTFMQKGTKFDIKRMVEDSDLQTCYCVFDVLMVNNKKLGHETLRKRYEILSSI
FTPIPGRIEIVQKTQAHTKNEVIDALNEAIDKREEGIMVKQPLSIYKPDKRGEGWLKI
KPEYVSGLMDELDILIVGGYWGKGSRGGMMSHFLCAVAEKPPPGEKPSVFHTLSRVGS
GCTMKELYDLGLKLAKYWKPFHRKAPPSSILCGTEKPEVYIEPCNSVIVQIKAAEIVP
SDMYKTGCTLRFPRIEKIRDDKEWHECMTLDDLEQLRGKASGKLASKHLYIGGDDEPQ
EKKRKAAPKMKKVIGIIEHLKAPNLTNVNKISNIFEDVEFCVMSGTDSQPKPDLENRI
AEFGGYIVQNPGPDTYCVIAGSENIRVKNIILSNKHDVVKPAWLLECFKTKSFVPWQP
RFMIHMCPSTKEHFAREYDCYGDSYFIDTDLNQLKEVFSGIKNSNEQTPEEMASLIAD
LEYRYSWDCSPLSMFRRHTVYLDSYAVINDLSTKNEGTRLAIKALELRFHGAKVVSCL
AEGVSHVIIGEDHSRVADFKAFRRTFKRKFKILKESWVTDSIDKCELQEENQYLI"
BASE COUNT 1381 a 618 c 783 g 1210 t
ORIGIN
1 cttctggcgc cagcttccgg cttagcggct gagcttcagg cttgacgtca ggaaaccatc
61 aagatctcat tttacagctg ggattctctg gttcacagag gtaacggagc ttgcccgagg
121 ccagttaaac gagaagattc atcaccgctt tgatggctgc ctcacaaact tcacaaactg
181 ttgcatctca cgttcctttt gcagatttgt gttcaacttt agaacgaata cagaaaagta
241 aaggacgtgc agaaaaaatc agacacttca gggaattttt agattcttgg agaaaatttc
301 atgatgctct tcataagaac cacaaagatg tcacagactc tttttatcca gcaatgagac
361 taattcttcc tcagctagaa agagagagaa tggcctatgg aattaaagaa actatgcttg
421 ctaagcttta tattgagttg cttaatttac ctagagatgg aaaagatgcc ctcaaacttt
481 taaactacag aacacccact ggaactcatg gagatgctgg agactttgca atgattgcat
541 attttgtgtt gaagccaaga tgtttacaga aaggaagttt aaccatacag caagtaaacg
601 accttttaga ctcaattgcc agcaataatt ctgctaaaag aaaagaccta ataaaaaaga
661 gccttcttca acttataact cagagttcag cacttgagca aaagtggctt atacggatga
721 tcataaagga tttaaagctt ggtgttagtc agcaaactat cttttctgtt tttcataatg
781 atgctgctga gttgcataat gtcactacag atctggaaaa agtctgtagg caactgcatg
841 atccttctgt aggactcagt gatatttcta tcactttatt ttctgcattt aaaccaatgc
901 tagctgctat tgcagatatt gagcacattg agaaggatat gaaacatcag agtttctaca
961 tagaaaccaa gctagatggt gaacgtatgc aaatgcacaa agatggagat gtatataaat
1021 acttctctcg aaatggatat aactacactg atcagtttgg tgcttctcct actgaaggtt
1081 ctcttacccc attcattcat aatgcattca aagcagatat acaaatctgt attcttgatg
1141 gtgagatgat ggcctataat cctaatacac aaactttcat gcaaaaggga actaagtttg
1201 atattaaaag aatggtagag gattctgatc tgcaaacttg ttattgtgtt tttgatgtat
1261 tgatggttaa taataaaaag ctagggcatg agactctgag aaagaggtat gagattctta
1321 gtagtatttt tacaccaatt ccaggtagaa tagaaatagt gcagaaaaca caagctcata
1381 ctaagaatga agtaattgat gcattgaatg aagcaataga taaaagagaa gagggaatta
1441 tggtaaaaca acctctatcc atctacaagc cagacaaaag aggtgaaggg tggttaaaaa
1501 ttaaaccaga gtatgtcagt ggactaatgg atgaattgga cattttaatt gttggaggat
1561 attggggtaa aggatcacgg ggtggaatga tgtctcattt tctgtgtgca gtagcagaga
1621 agccccctcc tggtgagaag ccatctgtgt ttcatactct ctctcgtgtt gggtctggct
1681 gcaccatgaa agaactgtat gatctgggtt tgaaattggc caagtattgg aagccttttc
1741 atagaaaagc tccaccaagc agcattttat gtggaacaga gaagccagaa gtatacattg
1801 aaccttgtaa ttctgtcatt gttcagatta aagcagcaga gatcgtaccc agtgatatgt
1861 ataaaactgg ctgcaccttg cgttttccac gaattgaaaa gataagagat gacaaggagt
1921 ggcatgagtg catgaccctg gacgacctag aacaacttag ggggaaggca tctggtaagc
1981 tcgcatctaa acacctttat ataggtggtg atgatgaacc acaagaaaaa aagcggaaag
2041 ctgccccaaa gatgaagaaa gttattggaa ttattgagca cttaaaagca cctaacctta
2101 ctaacgttaa caaaatttct aatatatttg aagatgtaga gttttgtgtt atgagtggaa
2161 cagatagcca gccaaagcct gacctggaga acagaattgc agaatttggt ggttatatag
2221 tacaaaatcc aggcccagac acgtactgtg taattgcagg gtctgagaac atcagagtga
2281 aaaacataat tttgtcaaat aaacatgatg ttgtcaagcc tgcatggctt ttagaatgtt
2341 ttaagaccaa aagctttgta ccatggcagc ctcgctttat gattcatatg tgcccatcaa
2401 ccaaagaaca ttttgcccgt gaatatgatt gctatggtga tagttatttc attgatacag
2461 acttgaacca actgaaggaa gtattctcag gaattaaaaa ttctaacgag cagactcctg
2521 aagaaatggc ttctctgatt gctgatttag aatatcggta ttcctgggat tgctctcctc
2581 tcagtatgtt tcgacgccac accgtttatt tggactcgta tgctgttatt aatgacctga
2641 gtaccaaaaa tgaggggaca aggttagcta ttaaagcctt ggagcttcgg tttcatggag
2701 caaaagtagt ttcttgttta gctgagggag tgtctcatgt aataattggg gaagatcata
2761 gtcgtgttgc agattttaaa gcttttagaa gaacttttaa gagaaagttt aaaatcctaa
2821 aagaaagttg ggtaactgat tcaatagaca agtgtgaatt acaagaagaa aaccagtatt
2881 tgatttaaag ctaggtttcc tagtgaggaa agcctctgat ctggcagact cattgcagca
2941 ggtggtaatg ataaaatact aaactacatt ttatttttgt atcttaaaaa tctatgccta
3001 aaaagtatca ttacatatag gaaaacaata attttaactt ttaaggttga aaagacaata
3061 gcccaaagcc aagaaagaaa aattatcttg aatgtagtat tcaatgattt tttatgatca
3121 aggtgaaata aacagtctaa agaagaggtg tttttataat atccatatag aaatctagaa
3181 tttttactta gatactaata aaatacattt agaaactttt aaagtcatga aaaagcatta
3241 accttctaaa cagtatattc taaaaagtca aaacgttaac aatagttttt atctaataaa
3301 agcactgcaa gaaaataggg tagaattgtt acagctggac ttgtaaaaat atgtttttac
3361 tcagggttta aaatgtccca tttaaatatg aaatgtaaac aaatttgttt tttaaggtta
3421 aggccaaatg taacaataaa accctgtcga tggttttagc taaattagag gaagttgtat
3481 gagacttaat gatctaaaaa cttaaaattg aattggtttg attaaaaata aagcttgcaa
3541 ttttaaaagt agctcacatt taatttcttg tgtgaaatag aacatgcttt aaaggaagta
3601 tttttatgtg aatttgcatt ccagtataaa tagtattcac aaaaaagatt ttcctagatt
3661 ttatctattg aataggtgtc aatatggcat gcatattgta actttcatta gaaataagtt
3721 gctttgactt ttaaaaatga catagttaga ttatttaaag tcaatgtata tagtatatat
3781 tatgtatgga tttatatacc aaattttgga atacagccta tctcatgacc atattgaaat
3841 gtacggaatt tgatccatgc gatactatgt gtgcattatt tgaaagttat tggaattttt
3901 attcaaaccg tggaacaaat gtatgtgatt ttgttatact tcttaattta aataaaatat
3961 ttaatgcact attaaaaaaa aaaaaaaaaa aa
//