LOCUS BC036755 4718 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens ligand of numb-protein X 2, mRNA (cDNA clone MGC:46315
IMAGE:5541168), complete cds.
ACCESSION BC036755
VERSION BC036755.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4718)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4718)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (23-AUG-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 25, 2003 this sequence version replaced BC036755.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 79 Row: a Column: 1
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 34222215.
FEATURES Location/Qualifiers
source 1..4718
/db_xref="H-InvDB:HIT000051795"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:46315 IMAGE:5541168"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_72"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..4718
/gene="LNX2"
/gene_synonym="MGC46315"
/db_xref="GeneID:222484"
/db_xref="HGNC:HGNC:20421"
/db_xref="MIM:609733"
CDS 139..2211
/gene="LNX2"
/gene_synonym="MGC46315"
/codon_start=1
/product="ligand of numb-protein X 2"
/protein_id="AAH36755.1"
/db_xref="GeneID:222484"
/db_xref="HGNC:HGNC:20421"
/db_xref="MIM:609733"
/translation="MGTTSDEMVSVEQTSSSSLNPLCFECGQQHWTRENHLYNYQNEV
DDDLVCHICLQPLLQPLDTPCGHTFCYKCLRNFLQEKDFCPLDRKRLHFKLCKKSSIL
VHKLLDKLLVLCPFSSVCKDVMQRCDLEAHLKNRCPGASHRRVALERRKTSRTQAEIE
NENGPTLLDPAGTLSPEADCLGTGAVPVERHLTSASLSTWSEEPGLDNPAFEESAGAD
TTQQPLSLPEGEITTIEIHRSNPYIQLGISIVGGNETPLINIVIQEVYRDGVIARDGR
LLAGDQILQVNNYNISNVSHNYARAVLSQPCNTLHLTVLRERRFGNRAHNHSDSNSPR
EEIFQVALHKRDSGEQLGIKLVRRTDEPGVFILDLLEGGLAAQDGRLSSNDRVLAING
HDLKYGTPELAAQIIQASGERVNLTIARPGKPQPGNTIREAGNHSSSSQHHTPPPYYS
RPSSHKDLTQCVTCQEKHITVKKEPHESLGMTVAGGRGSKSGELPIFVTSVPPHGCLA
RDGRIKRGDVLLNINGIDLTNLSHSEAVAMLKASAASPAVALKALEVQIVEEATQNAE
EQPSTFSENEYDASWSPSWVMWLGLPSTLHSCHDIVLRRSYLGSWGFSIVGGYEENHT
NQPFFIKTIVLGTPAYYDGRLKCGDMIVAVNGLSTVGMSHSALVPMLKEQRNKVTLTV
ICWPGSLV"
BASE COUNT 1419 a 908 c 985 g 1406 t
ORIGIN
1 ggacgcgtgg gcgcggcccg ggcagccgcg ctttcccaaa aaacacacct tgactttagt
61 cagatacatc actgtctgtt aaaggaaacc aagcgtgaag tggaagtcta acacatgagg
121 atacagaatt gattcaaaat gggaacaaca agtgatgaga tggtgtctgt ggaacagacc
181 tcctcctctt ctctaaaccc cctgtgtttt gaatgtggcc aacagcactg gacaagagaa
241 aaccatttgt acaattacca gaatgaagtg gatgatgacc tagtctgcca tatttgcctt
301 caacctctgc tgcagccact agacacaccc tgtggacata cattctgcta caagtgcctc
361 agaaactttt tacaagagaa agatttctgt ccgttggacc ggaaaagact tcattttaag
421 ttgtgcaaga agtctagtat tctagttcat aaactcctag acaaattatt agttttatgt
481 ccattttctt cagtgtgcaa agatgtaatg caacgttgtg atctggaggc acatctcaaa
541 aacagatgtc ctggagcttc tcatcggaga gttgccctgg agagaaggaa aactagtaga
601 actcaagcag agattgagaa tgaaaatggg cccactctac tagatcctgc aggtacctta
661 tctccagaag cagactgttt ggggacaggc gcagtgcctg tggagcggca cttgacatca
721 gcgtctcttt ccacatggag tgaggagcct ggccttgaca accctgcctt tgaggagagc
781 gctggagctg acaccacaca acagccactt agtttaccag aaggagaaat caccacgatt
841 gaaattcatc ggtccaatcc ttacattcag ttaggaatca gcattgtggg tggcaacgaa
901 acacctttga ttaacattgt catccaggag gtctatcggg atggggtcat tgccagagac
961 gggagacttc ttgctggaga ccagattctt caggtcaaca actacaatat cagcaatgtg
1021 tcccataact atgcccgagc tgtcctttcc cagccctgca acacactgca tcttactgtg
1081 cttcgagaga ggcgctttgg caaccgagca cacaaccatt ctgatagtaa ctctccacga
1141 gaagagattt tccaagtggc tcttcataaa cgggactctg gtgaacagct tggcattaaa
1201 ttggtgcgaa ggacagatga gccaggggtt tttattcttg acctgttgga aggggggttg
1261 gctgcccagg acggcaggct aagcagcaat gaccgagtgc tggccatcaa tgggcacgac
1321 ctgaagtatg gaactccgga gcttgctgcc cagattattc aggccagtgg agagagagtg
1381 aatttaacaa ttgctagacc agggaaaccc cagcctggta acaccattag agaagcagga
1441 aatcatagca gcagcagcca gcaccacaca ccaccaccgt attatagcag accaagctca
1501 cataaggatc ttactcagtg tgttacatgc caagaaaaac acattactgt aaagaaggaa
1561 ccacatgaat cccttggcat gaccgttgct gggggcaggg gaagtaagag tggtgagctg
1621 cccatctttg tgaccagtgt gccaccccat ggctgccttg cacgagatgg cagaataaag
1681 agaggtgatg tgttgctaaa tatcaacggc attgatttga ccaatttaag tcacagtgag
1741 gcagttgcaa tgctgaaagc cagtgccgcg tcccctgctg ttgcccttaa agcacttgag
1801 gtccagattg ttgaggaggc gactcagaac gcggaggagc agccgagtac tttcagcgaa
1861 aatgagtatg atgccagttg gtccccatca tgggtcatgt ggcttgggct tcccagcaca
1921 cttcatagct gccacgatat agttttacga agaagttact tgggaagttg gggctttagt
1981 atcgttggtg gatatgaaga gaaccacacc aatcagcctt ttttcattaa aactattgtc
2041 ttgggaactc ctgcttatta tgatggaaga ttaaagtgtg gtgacatgat tgtggccgta
2101 aatgggctgt caaccgtggg catgagccac tctgcactag ttcccatgtt gaaggagcag
2161 aggaacaaag tcactctgac cgttatttgt tggcctggca gccttgtata gattttggaa
2221 attggtttca aatcttgcat cttccttttt tagatttttg aaagaaaacc ctttggtttc
2281 attgtgtttg tggtttagga gctgctgaca ctgctggtat acacagggcc aaaacccact
2341 aagattgtcc gtttatgttt atttaaatgg tttcctaagt tagttacatt tcttttagct
2401 tggaaacagt cttccactaa cctttgtgag tttatatttt cagaattcag acttagttgt
2461 taaaatgtta cctatggtaa tgagcaaagc tcacccaaac tgtgccccag atggagtaaa
2521 gaccttctgg tgggtctttg ttttcagtaa ctgaatcata gaacgagttc tgtatccctc
2581 aggcctgatg tcagcaaagc cagtaacaac agcgtgtact gccactgtca taaccaatac
2641 catgaatgaa tatactttaa attttggtga taactgttcc ccattttttt ttgaaccacg
2701 gtctcactct cacccaggct ggagtgcagt ggcacaatct cagctcactg caagctccgc
2761 ctcctgggtt cacgccattc tcccgcctca gcctcccgag tagctgggac tacaggcgtg
2821 tgccaccatg cccagctaat tttttgtact tttagtagag acggggtttc gccgtgttgg
2881 ccaggatggt ctcgatctcc tgaccttgtg atctgcccgc ctcagcctcc caaagtgctg
2941 ggattacagg tgtgagctgc cgcacccggc cgttcccatt ttttattggt gccaacattt
3001 caaaacttca tactgtttat aaactgattt tctggtttat ttctactgta atctctcaat
3061 attcatagaa gatgaagaaa taagtctgac aacactaaag aaatttctta atatactatt
3121 attagaatag tagaggataa aagataatgt tatccagtta caaaggaatt tggatgataa
3181 ttataactta atgttagaga tggtaaagct gcacttactt gaacagccca aaagcattaa
3241 aaatctattt ccagaggaat gttttgctat gtagggaaat tttgaagtag tttttgctaa
3301 aaaattattt ctagagttgt gttattctta gcagtaatct tggctagaaa tgtttttgtg
3361 atttatgcga ttaaacgaaa tgataaagat aaaaccatat tattaaatac ctatatatca
3421 cagctaagta ggagaaaggg agaccttttt attttgttca ggtaggagta tttcttgtgt
3481 attttagaaa caattatttt tcccattatt tcttatgaga ttagttgttt caagtaggag
3541 acagaaaagt tctgttttgt tggaaatgta ggttttagat gtatctttca gtcagctctc
3601 agtcactaga ctatttcata ttttttgaaa tgtttttgaa aattatgact agcccatttt
3661 ttgtccttta ttcaacatac ttatcctctg aacacataaa taagtgaata agataaaaat
3721 atctttacct tattaatatt atacatactt gaaaaaaatt tcatttagaa acctagttca
3781 gaatctgagc aaatttacaa gtgacctctg taataaatgg tattgataat cagagaatgt
3841 atttcagaat actacagtac aatatattat gaagcatgac cactttattt tgaaacttag
3901 caattgtatt gctggggttt attgtatctg tagcatgtca ctgattattt cagttagttt
3961 tataatgatt tttaaaaaac atatctattt ggaataagat acagcaacaa tcattgctac
4021 tgacttgttc aaccccttag ttacactgta tgatcaacat ataacaagat acagtggaat
4081 ggcccataca gtatattact gttgtgtgat gattggcttt ggaagcagtt tgattttgaa
4141 atgctttgat attctaattg acatggaaca agttttttcc ctgctcccca aatagaattt
4201 tgtaaccaac tttgctattt ttttaaagtt tgtaagaatg tgtcatttct tggggagtag
4261 ccatccatca acaaatatcc tgactgctac tttgttatat acaaaatact tacattgaac
4321 ctggtggcat aatgagtatt ttgaaagaag aaatttcttc actctcattt ttatagaaat
4381 cttggaatca gcttaagctg tagcttttat gacaaaagac agtcattttt ggtcagagtg
4441 atatttggtg acggaaactt gttcataatt tattgttact atagaactat ttggattttc
4501 tcatttttag ttctgatagt taaatatttt ggtttgttct gtgccttcag tttaaattat
4561 ttcaggattt ttcagatgtt taaataatgg tgtgaatcat tcaggatgga aataaaagtc
4621 atcctttctg taaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
4681 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//