LOCUS BC036515 4665 bp mRNA linear HUM 11-AUG-2006
DEFINITION Homo sapiens ADAM metallopeptidase with thrombospondin type 1
motif, 1, mRNA (cDNA clone MGC:32979 IMAGE:5266513), complete cds.
ACCESSION BC036515
VERSION BC036515.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4665)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4665)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (16-AUG-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 25, 2003 this sequence version replaced BC036515.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 47 Row: k Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 50845383.
FEATURES Location/Qualifiers
source 1..4665
/db_xref="H-InvDB:HIT000051723"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:32979 IMAGE:5266513"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..4665
/gene="ADAMTS1"
/gene_synonym="C3-C5"
/gene_synonym="KIAA1346"
/gene_synonym="METH1"
/db_xref="GeneID:9510"
/db_xref="HGNC:HGNC:217"
/db_xref="MIM:605174"
CDS 456..3359
/gene="ADAMTS1"
/gene_synonym="C3-C5"
/gene_synonym="KIAA1346"
/gene_synonym="METH1"
/codon_start=1
/product="ADAM metallopeptidase with thrombospondin type 1
motif, 1"
/protein_id="AAH36515.1"
/db_xref="GeneID:9510"
/db_xref="HGNC:HGNC:217"
/db_xref="MIM:605174"
/translation="MQRAVPEGFGRRKLGSDMGNAERAPGSRSFGPVPTLLLLAAALL
AVSDALGRPSEEDEELVVPELERAPGHGTTRLRLHAFDQQLDLELRPDSSFLAPGFTL
QNVGRKSGSETPLPETDLAHCFYSGTVNGDPSSAAALSLCEGVRGAFYLLGEAYFIQP
LPAASERLATAAPGEKPPAPLQFHLLRRNRQGDVGGTCGVVDDEPRPTGKAETEDEDE
GTEGEDEGPQWSPQDPALQGVGQPTGTGSIRKKRFVSSHRYVETMLVADQSMAEFHGS
GLKHYLLTLFSVAARLYKHPSIRNSVSLVVVKILVIHDEQKGPEVTSNAALTLRNFCN
WQKQHNPPSDRDAEHYDTAILFTRQDLCGSQTCDTLGMADVGTVCDPSRSCSVIEDDG
LQAAFTTAHELGHVFNMPHDDAKQCASLNGVNQDSHMMASMLSNLDHSQPWSPCSAYM
ITSFLDNGHGECLMDKPQNPIQLPGDLPGTSYDANRQCQFTFGEDSKHCPDAASTCST
LWCTGTSGGVLVCQTKHFPWADGTSCGEGKWCINGKCVNKTDRKHFDTPFHGSWGMWG
PWGDCSRTCGGGVQYTMRECDNPVPKNGGKYCEGKRVRYRSCNLEDCPDNNGKTFREE
QCEAHNEFSKASFGSGPAVEWIPKYAGVSPKDRCKLICQAKGIGYFFVLQPKVVDGTP
CSTDSTSVCVQGQCVKAGCDRIIDSKKKFDKCGVCGGNGSTCKKISGSVTSAKPGYHD
IITIPTGATNIEVKQRNQRGSRNNGSFLAIKAADGTYILNGDYTLSTLEQDIMYKGVV
LRYSGSSAALERIRSFSPLKEPLTIQVLTVGNALRPKIKYTYFVKKKKESFNAIPTFS
AWVIEEWGECSKSCELGWQRRLVECRDINGQPASECAKEVKPASTRPCADHPCPQWQL
GEWSSCSKTCGKGYKKRSLKCLSHDGGVLSHESCDPLKKPKHFIDFCTMAECS"
BASE COUNT 1242 a 1086 c 1257 g 1080 t
ORIGIN
1 gcactcgctg gaaagcggct ccgagccagg ggctattgca aagccagggt gcgctaccgg
61 acggagaggg gagagccctg agcagagtga gcaacatcgc agccaaggcg gaggccgaag
121 aggggcgcca ggcaccaatc tccgcgttgc ctcagccccg gaggcgcccc agagcgcttc
181 ttgtcccagc agagccactc tgcctgcgcc tgcctctcag tgtctccaac tttgcgctgg
241 aagaaaaact tcccgcgcgc cggcagaact gcagcgcctc ctcttagtga ctccgggagc
301 ttcggctgta gccggctctg cgcgcccttc caacgaataa tagaaattgt taattttaac
361 aatccagagc aggccaacga ggctttgctc tcccgacccg aactaaagct ccctcgctcc
421 gtgcgctgct acgagcggtg tctcctgggg ctccaatgca gcgagctgtg cccgaggggt
481 tcggaaggcg caagctgggc agcgacatgg ggaacgcgga gcgggctccg gggtctcgga
541 gctttgggcc cgtacccacg ctgctgctgc tcgccgcggc gctactggcc gtgtcggacg
601 cactcgggcg cccctccgag gaggacgagg agctagtggt gccggagctg gagcgcgccc
661 cgggacacgg gaccacgcgc ctccgcctgc acgcctttga ccagcagctg gatctggagc
721 tgcggcccga cagcagcttt ttggcgcccg gcttcacgct ccagaacgtg gggcgcaaat
781 ccgggtccga gacgccgctt ccggaaaccg acctggcgca ctgcttctac tccggcaccg
841 tgaatggcga tcccagctcg gctgccgccc tcagcctctg cgagggcgtg cgcggcgcct
901 tctacctgct gggggaggcg tatttcatcc agccgctgcc cgccgccagc gagcgcctcg
961 ccaccgccgc cccaggggag aagccgccgg caccactaca gttccacctc ctgcggcgga
1021 atcggcaggg cgacgtaggc ggcacgtgcg gggtcgtgga cgacgagccc cggccgactg
1081 ggaaagcgga gaccgaagac gaggacgaag ggactgaggg cgaggacgaa gggcctcagt
1141 ggtcgccgca ggacccggca ctgcaaggcg taggacagcc cacaggaact ggaagcataa
1201 gaaagaagcg atttgtgtcc agtcaccgct atgtggaaac catgcttgtg gcagaccagt
1261 cgatggcaga attccacggc agtggtctaa agcattacct tctcacgttg ttttcggtgg
1321 cagccagatt gtacaaacac cccagcattc gtaattcagt tagcctggtg gtggtgaaga
1381 tcttggtcat ccacgatgaa cagaaggggc cggaagtgac ctccaatgct gccctcactc
1441 tgcggaactt ttgcaactgg cagaagcagc acaacccacc cagtgaccgg gatgcagagc
1501 actatgacac agcaattctt ttcaccagac aggacttgtg tgggtcccag acatgtgata
1561 ctcttgggat ggctgatgtt ggaactgtgt gtgatccgag cagaagctgc tccgtcatag
1621 aagatgatgg tttacaagct gccttcacca cagcccatga attaggccac gtgtttaaca
1681 tgccacatga tgatgcaaag cagtgtgcca gccttaatgg tgtgaaccag gattcccaca
1741 tgatggcgtc aatgctttcc aacctggacc acagccagcc ttggtctcct tgcagtgcct
1801 acatgattac atcatttctg gataatggtc atggggaatg tttgatggac aagcctcaga
1861 atcccataca gctcccaggc gatctccctg gcacctcgta cgatgccaac cggcagtgcc
1921 agtttacatt tggggaggac tccaaacact gccctgatgc agccagcaca tgtagcacct
1981 tgtggtgtac cggcacctct ggtggggtgc tggtgtgtca aaccaaacac ttcccgtggg
2041 cggatggcac cagctgtgga gaagggaaat ggtgtatcaa cggcaagtgt gtgaacaaaa
2101 ccgacagaaa gcattttgat acgccttttc atggaagctg gggaatgtgg gggccttggg
2161 gagactgttc gagaacgtgc ggtggaggag tccagtacac gatgagggaa tgtgacaacc
2221 cagtcccaaa gaatggaggg aagtactgtg aaggcaaacg agtgcgctac agatcctgta
2281 accttgagga ctgtccagac aataatggaa aaacctttag agaggaacaa tgtgaagcac
2341 acaacgagtt ttcaaaagct tcctttggga gtgggcctgc ggtggaatgg attcccaagt
2401 acgctggcgt ctcaccaaag gacaggtgca agctcatctg ccaagccaaa ggcattggct
2461 acttcttcgt tttgcagccc aaggttgtag atggtactcc atgtagcaca gattccacct
2521 ctgtctgtgt gcaaggacag tgtgtaaaag ctggttgtga tcgcatcata gactccaaaa
2581 agaagtttga taaatgtggt gtttgcgggg gaaatggatc tacttgtaaa aaaatatcag
2641 gatcagttac tagtgcaaaa cctggatatc atgatatcat cacaattcca actggagcca
2701 ccaacatcga agtgaaacag cggaaccaga ggggatccag gaacaatggc agctttcttg
2761 ccatcaaagc tgctgatggc acatatattc ttaatggtga ctacactttg tccaccttag
2821 agcaagacat tatgtacaaa ggtgttgtct tgaggtacag cggctcctct gcggcattgg
2881 aaagaattcg cagctttagc cctctcaaag agcccttgac catccaggtt cttactgtgg
2941 gcaatgccct tcgacctaaa attaaataca cctacttcgt aaagaagaag aaggaatctt
3001 tcaatgctat ccccactttt tcagcatggg tcattgaaga gtggggcgaa tgttctaagt
3061 catgtgaatt gggttggcag agaagactgg tagaatgccg agacattaat ggacagcctg
3121 cttccgagtg tgcaaaggaa gtgaagccag ccagcaccag accttgtgca gaccatccct
3181 gcccccagtg gcagctgggg gagtggtcat catgttctaa gacctgtggg aagggttaca
3241 aaaaaagaag cttgaagtgt ctgtcccatg atggaggggt gttatctcat gagagctgtg
3301 atcctttaaa gaaacctaaa catttcatag acttttgcac aatggcagaa tgcagttaag
3361 tggtttaagt ggtgttagct ttgagggcaa ggcaaagtga ggaagggctg gtgcagggaa
3421 agcaagaagg ctggagggat ccagcgtatc ttgccagtaa ccagtgaggt gtatcagtaa
3481 ggtgggatta tgggggtaga tagaaaagga gttgaatcat cagagtaaac tgccagttgc
3541 aaatttgata ggatagttag tgaggattat taacctctga gcagtgatat agcataataa
3601 agccccgggc attattatta ttatttcttt tgttacatct attacaagtt tagaaaaaac
3661 aaagcaattg tcaaaaaaag ttagaactat tacaacccct gtttcctggt acttatcaaa
3721 tacttagtat catgggggtt gggaaatgaa aagtaggaga aaagtgagat tttactaaga
3781 cctgttttac tttacctcac taacaatggg gggagaaagg agtacaaata ggatctttga
3841 ccagcactgt ttatggctgc tatggtttca gagaatgttt atacattatt tctaccgaga
3901 attaaaactt cagattgttc aacatgagag aaaggctcag caacgtgaaa taacgcaaat
3961 ggcttcctct ttcctttttt ggaccatctc agtctttatt tgtgtaattc attttgagga
4021 aaaaacaact ccatgtattt attcaagtgc attaaagtct acaatggaaa aaaagcagtg
4081 aagcattaga tgctggtaaa agctagagga gacacaatga gcttagtacc tccaacttcc
4141 tttctttcct accatgtaac cctgctttgg gaatatggat gtaaagaagt aacttgtgtc
4201 tcatgaaaat cagtacaatc acacaaggag gatgaaacgc cggaacaaaa atgaggtgtg
4261 tagaacaggg tcccacaggt ttggggacat tgagatcact tgtcttgtgg tggggaggct
4321 gctgaggggt agcaggtcca tctccagcag ctggtccaac agtcgtatcc tggtgaatgt
4381 ctgttcagct cttctgtgag aatatgattt tttccatatg tatatagtaa aatatgttac
4441 tataaattac atgtacttta taagtattgg tttgggtgtt ccttccaaga aggactatag
4501 ttagtaataa atgcctataa taacatattt atttttatac atttatttct aatgaaaaaa
4561 acttttaaat tatatcgctt ttgtggaagt gcatataaaa tagagtattt atacaatata
4621 tgttactaga aataaaagaa cacttttgga aaaaaaaaaa aaaaa
//