LOCUS BC036445 4178 bp mRNA linear HUM 22-FEB-2007
DEFINITION Homo sapiens aggrecan, mRNA (cDNA clone IMAGE:4823544), complete
cds.
ACCESSION BC036445
VERSION BC036445.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4178)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4178)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (09-AUG-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 33 Row: g Column: 8
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4501990
This clone has the following problem: The cds is short compared to
the longest cds in the locus.
FEATURES Location/Qualifiers
source 1..4178
/db_xref="H-InvDB:HIT000051698"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4823544"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..4178
/gene="ACAN"
/gene_synonym="AGCAN"
/gene_synonym="CSPGCP"
/gene_synonym="SEDK"
/db_xref="GeneID:176"
/db_xref="HGNC:HGNC:319"
/db_xref="MIM:155760"
CDS 346..2511
/gene="ACAN"
/gene_synonym="AGCAN"
/gene_synonym="CSPGCP"
/gene_synonym="SEDK"
/codon_start=1
/product="aggrecan"
/protein_id="AAH36445.1"
/db_xref="GeneID:176"
/db_xref="HGNC:HGNC:319"
/db_xref="MIM:155760"
/translation="MTTLLWVFVTLRVITAAVTVETSDHDNSLSVSIPQPSPLRVLLG
TSLTIPCYFIDPMHPVTTAPSTAPLAPRIKWSRVSKEKEVVLLVATEGRVRVNSAYQD
KVSLPNYPAIPSDATLEVQSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRAI
STRYTLDFDRAQRACLQNSAIIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPRE
GCYGDKDEFPGVRTYGIRDTNETYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRL
GARLATTGQLYLAWQAGMDMCSAGWLADRSVRYPISKARPNCGGNLLGVRTVYVHANQ
TGYPDPSSRYDAICYTGEDFVDIPENFFGVGGEEDITVQTVTWPDMELPLPRNITEGE
ARGSVILTVKPIFEVSPSPLEPEEPFTFAPEIGATAFAEVENETGEATRPWGFPTPGL
GPATAFTSEDLVVQVTAVPGQPHLPGGVVFHYRPGPTRYSLTFEEAQQACLRTGAVIA
SPEQLQAAYEAGYEQCDAGWLRDQTVRYPIVSPRTPCVGDKDSSPGVRTYGVRPSTET
YDVYCFVDRLEGEVFFATRLEQFTFQEALEFCESHNATLATTGQLYAAWSRGLDKCYA
GWLADGSLRYPIVTPRPACGGDKPGVRTVYLYPNQTGLPDPLSRHHAFCFRGMQPHFG
SNSPFCLERTPLGSPDPATTQYPIHQSKKMSVPLGQSQL"
BASE COUNT 958 a 1233 c 1082 g 905 t
ORIGIN
1 agcggagtgc tgaggacgcg cgcagcgctg ctcaaggtct ctctctctca gcaccctcgc
61 cggccggcgt ctgacgcggg tgccagggtc tccgggcacc tttcagtgtc cattccctca
121 gccagccagg actccgcaac ccagcagttg ccgctgcggc cacagcccga ggggacctgc
181 ggacaggacg ccggcaggag gaggggtgcg cagcgcccgc gcagagcgtc tccctcgcta
241 cgcagcgaga cccgggcctc ccggccccag gagcccccag ctgcctcgcc aggtgtgtgg
301 gactgaagtt cttggagaag ggagtccaac tcttcaaggt gaactatgac cactttactc
361 tgggttttcg tgactctgag ggtcatcact gcagctgtca ctgtagaaac ttcagaccat
421 gacaactcgc tgagtgtcag catcccccaa ccgtccccgc tgagggtcct cctggggacc
481 tccctcacca tcccctgcta tttcatcgac cccatgcacc ctgtgaccac cgccccttct
541 accgccccac tggccccaag aatcaagtgg agccgtgtgt ccaaggagaa ggaggtagtg
601 ctgctggtgg ccactgaagg gcgcgtgcgg gtcaacagtg cctatcagga caaggtctca
661 ctgcccaact acccggccat ccccagtgac gccaccttgg aagtccagag cctgcgctcc
721 aatgactctg gggtctaccg ctgcgaggtg atgcatggca tcgaggacag cgaggccacc
781 ctggaagtcg tggtgaaagg catcgtgttc cattacagag ccatctctac acgctacacc
841 ctcgactttg acagggcgca gcgggcctgc ctgcagaaca gtgccatcat tgccacgcct
901 gagcagctgc aggccgccta cgaagacggc ttccaccagt gtgacgccgg ctggctggct
961 gaccagactg tcagataccc catccacact ccccgggaag gctgctatgg agacaaggat
1021 gagtttcctg gtgtgaggac gtatggcatc cgagacacca acgagaccta tgatgtgtac
1081 tgcttcgccg aggagatgga gggtgaggtc ttttatgcaa catctccaga gaagttcacc
1141 ttccaggaag cagccaatga gtgccggcgg ctgggtgccc ggctggccac cacgggccag
1201 ctctacctgg cctggcaggc tggcatggac atgtgcagcg ccggctggct ggccgaccgc
1261 agcgtgcgct accccatctc caaggcccgg cccaactgcg gtggcaacct cctgggcgtg
1321 aggaccgtct acgtgcatgc caaccagacg ggctaccccg acccctcatc ccgctacgac
1381 gccatctgct acacaggtga agactttgtg gacatcccag aaaacttctt tggagtgggg
1441 ggtgaggagg acatcaccgt ccagacagtg acctggcctg acatggagct gccactgcct
1501 cgaaacatca ctgagggtga agcccgaggc agcgtgatcc ttaccgtaaa gcccatcttc
1561 gaggtctccc ccagtcccct ggaacccgag gagcccttca cgtttgcccc tgaaataggg
1621 gccactgcct tcgctgaggt tgagaatgag actggagagg ccaccaggcc ctggggcttt
1681 cccacacctg gcctgggccc tgccacggca ttcaccagtg aggacctcgt cgtgcaggtg
1741 accgctgtcc ctgggcagcc gcatttgcca gggggggtcg tcttccacta ccgcccggga
1801 cccacccgct actcgctgac ctttgaggag gcacagcagg cctgcctgcg cacgggggcg
1861 gtcattgcct cgccggagca gctccaggcc gcctacgaag caggctatga gcagtgtgac
1921 gccggctggc tgcgggacca gaccgtcaga taccccattg tgagcccccg gaccccatgc
1981 gtgggtgaca aggacagcag cccaggggtc aggacctatg gcgtgcgccc atcaacagag
2041 acctacgatg tctactgctt tgtagacaga cttgaggggg aggtgttctt cgccacacgc
2101 cttgagcagt tcaccttcca ggaagcactg gagttctgtg aatctcacaa tgccacgctg
2161 gccaccacgg gccagctcta cgccgcctgg agccgcggcc tggacaagtg ctatgccggc
2221 tggctggccg acggcagcct ccgctacccc atcgtcaccc caaggcctgc ctgcggtggg
2281 gacaagccag gcgtgagaac ggtctacctc taccctaacc agacgggcct cccagaccca
2341 ctgtcccggc accatgcctt ctgcttccga ggtatgcagc ctcacttcgg ctccaacagc
2401 cccttttgtc tggagaggac cccactgggt tcaccggatc ctgccaccac ccagtatccc
2461 atccatcaga gcaagaaaat gtcagtccct ctggggcaga gccagctctg aaaccagcac
2521 aacgcaggct ttgaccccaa ggcaaggtca tccttctaaa gttccccaga gacaagtaga
2581 gataaataag aacttgagct ggtatttatg tctactagat atgaagcaga cctgaatttg
2641 agttatggct ctgctactta atagctgtgt gaaaatggag atatgatggt tcctacttca
2701 gagagagctg caagaattaa ttaagtgcac gtggtgccct tggcatagtg cctgggacac
2761 agtaaatgct caataaatgt tagctttatt tcatatacat atctatatgt aaagctgtaa
2821 tatatagctt tattttgtac aacctgtaat ttgtacactc ttgtcaaatt ctctcctgct
2881 tgcaaatatt tttgtgatga gtttagtcaa attattctat tattcttcac taagcactgg
2941 tggttcaagt ttttcgttga cctatgctat ggatatgcta ccatttcaac catcactccc
3001 cactggactt ctgagagtga tgtcatcaag caatatagta agcatggcca gggcatagcc
3061 acggaattgc tgggctctgg atgagttcct gcagagtcca tggagggtct gggtgcatgg
3121 accagaatgt agattgtaat aacagcctgt gccatgtttt atagtttaca tcaaaactga
3181 gtgtctttgc aacttcctgt gaatctagaa ttattctcaa ataaacttaa ggggaaaaaa
3241 cttgagtgtc cccaagtttc ccagacatcc agggtcacct tttaaaaccc aattcaaggc
3301 caggagcagt ggcttacgcc tgtaatccca gcactttggg aggccaaggc aggcagatca
3361 cttgaggtta ggagttcgag atcagcctgg ccaacatggt gaaaccctgt ctctactaaa
3421 aaaaagtgca aaaattagcc tagtttggtg gtgtgtacct gtaatcccag ctactaggga
3481 ggctgaggca ggagaatcac ctcaacccag gaggcggagg ttgcagtgag ccgagattat
3541 tctgctctac tccagcctgg gcagcagagc aagactctgt ctcaaaaaaa aaaaaaaaaa
3601 ttcaaagttc agccagcctc aataagtcaa gtccaattct ctcccagagg ctttgatgag
3661 gctcttgtcc cagtgcccct tccctgctct gggaagcaga aaccaagcca gttaacctcc
3721 cagaaatttc ccagccatgc tgcccccagc ctcccacccc tgaccctccg tgaactcagc
3781 cttgtgtatt atcctgcaca gttcagcttc cttgctgacc aagcccactg ctggtttccc
3841 ccacaccagt acagttaccc ccagcccatg aatcctgcct tcacgctttc aaatgccgag
3901 atggtttcat ggaattgagt accatcctcc tatttttggt cgtgacacac ttggaacata
3961 atccctgtcc cccaaggttg ttcagtagtt gagagcgtgg agtctggtac cagatgctta
4021 aattcaaaga ctagatctga catttgtaag ccattgtctc tgggcaaatc atgtaactct
4081 gtgcctcagt ttccccatct gtaaaatgag ataatcatat ctctctcata aagctgttgt
4141 gagataaagt gattttagat acaaaaaaaa aaaaaaaa
//