LOCUS BC036381 4656 bp mRNA linear HUM 06-JUN-2006
DEFINITION Homo sapiens Smg-7 homolog, nonsense mediated mRNA decay factor (C.
elegans), mRNA (cDNA clone MGC:33347 IMAGE:4829267), complete cds.
ACCESSION BC036381
VERSION BC036381.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4656)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4656)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-AUG-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 47 Row: c Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 42476069.
FEATURES Location/Qualifiers
source 1..4656
/db_xref="H-InvDB:HIT000259080"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:33347 IMAGE:4829267"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..4656
/gene="SMG7"
/gene_synonym="EST1C"
/gene_synonym="KIAA0250"
/gene_synonym="SGA56M"
/gene_synonym="SMG-7"
/db_xref="GeneID:9887"
/db_xref="HGNC:HGNC:16792"
CDS 119..3655
/gene="SMG7"
/gene_synonym="EST1C"
/gene_synonym="KIAA0250"
/gene_synonym="SGA56M"
/gene_synonym="SMG-7"
/codon_start=1
/product="SMG7 protein"
/protein_id="AAH36381.1"
/db_xref="GeneID:9887"
/db_xref="HGNC:HGNC:16792"
/translation="MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKML
VTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFY
TQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGD
IARYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFP
FPAASTNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKL
EEQFKRLLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLAL
FMSFLGILCKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPW
LISLLNSFHPHEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQ
QRRIRQQRLISIGKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQE
TSVIESLAADGSPGLKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPP
KEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYV
IPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGP
MNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHS
GFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQP
LEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGIFR
PEQDPVPRMPFEDPKSSPLLPPDLLKSLAALEEEEELIFSNTPDLYPALLGPLASLPG
RSLFKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSP
SMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPF
SNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGH
GPSMEDSSAVLMESLKKQQHGVQQLGPKRQSEEEGSSSICVAHRGPRPLPSCSLPAST
FRVKFKAARTCAHQAQKKTRRRPFWKRRKKGK"
BASE COUNT 1255 a 1203 c 1049 g 1149 t
ORIGIN
1 agcgggaggg gaggaagatg gcggcggccg ccagcacccg cggtgccgcg gggccgctcc
61 gaggagcctg agagacccac ggaggcttcg cgggaagacg cggcggcggc ggcggaggat
121 gagcctgcag agcgcgcagt acctccggca ggcagaagtc ctgaaggctg acatgacaga
181 ttctaagctg ggtccagctg aagtctggac atccaggcag gctctgcagg acctgtacca
241 gaaaatgcta gttaccgatt tggaatacgc tttagacaag aaagtagaac aggatctctg
301 gaatcacgcc tttaagaatc agatcacaac actacaaggc caggcaaaga atcgagcaaa
361 tccgaatcgg agtgaagttc aggcaaacct ttctctgttc ctagaggcag ctagtggctt
421 ctatactcag ttattacaag aactgtgtac agtatttaat gtagatttac catgccgtgt
481 gaagtcttcc caattgggaa ttatcagcaa taaacagacg cataccagcg ccatagtgaa
541 gccacagtct agctcctgtt cctatatctg ccagcactgc ctcgtccacc ttggagacat
601 tgctcgatac agaaaccaga ccagccaggc agagtcctac tataggcatg cagctcagct
661 tgtcccctcc aatggtcagc cttataatca gttggctatc ttagcttctt ccaaaggaga
721 ccatctgacc acaattttct actactgcag aagcattgct gtgaagttcc ctttcccagc
781 tgcctccact aatctgcaaa aagcactttc taaagcactg gaaagccgag atgaggtgaa
841 aaccaagtgg ggtgtttctg acttcatcaa ggcctttatt aaattccacg gtcatgtgta
901 cctgagtaag agcttggaaa agttgagccc tcttcgagag aaattggaag aacagtttaa
961 gaggctgcta ttccaaaaag ctttcaactc tcagcagtta gttcatgtca ctgtcattaa
1021 cctgtttcaa cttcatcacc ttcgtgactt tagcaatgaa accgagcagc acacttatag
1081 ccaagatgag cagctatgtt ggacacagtt gctggccctc tttatgtctt ttctcggcat
1141 cctgtgcaag tgtcctctac agaatgagtc tcaggaggag tcctacaatg cctatcctct
1201 tccagcagtc aaggtctcca tggactggct aagactcaga cccagggtct ttcaggaggc
1261 agtggtggat gaaagacagt acatttggcc ctggttgatt tctcttctga atagtttcca
1321 tccccatgaa gaggacctct caagtattag tgcgacacca cttccagagg agtttgaatt
1381 acaaggattt ttggcattga gaccttcttt caggaacttg gatttttcca aaggtcacca
1441 gggtattaca ggggacaaag aaggccagca acgacgaata cgacagcaac gcttgatctc
1501 tataggcaaa tggattgctg ataatcagcc aaggctgatt cagtgtgaaa atgaggtagg
1561 gaaattgttg tttatcacag aaatcccaga attaatactg gaagacccca gtgaagccaa
1621 agagaacctc attctgcaag aaacatctgt gatagagtcg ctggctgcag atgggagccc
1681 agggctaaaa tcagtgctat ctacaagccg aaatttaagc aacaactgtg acacaggaga
1741 gaagccagtg gttaccttca aagaaaacat taagacacga gaagtgaaca gagaccaagg
1801 aagaagtttt cctcccaaag aggtaaaatc ccagacagaa ctaagaaaga ctccagtgtc
1861 tgaagccaga aaaacacctg taactcaaac cccaactcaa gcaagtaact cccagttcat
1921 ccccattcat caccctggag ccttccctcc tcttcccagc aggccagggt ttccgccccc
1981 aacatatgtt atccccccgc ctgtggcatt ttctatgggc tcaggttaca ccttcccagc
2041 tggtgtttct gtcccaggaa cctttcttca gcctacagct cactctccag caggaaacca
2101 ggtgcaagct gggaaacagt cccacattcc ttacagccag caacggccct ctggaccagg
2161 gccaatgaac cagggacctc aacaatcaca gccaccttcc cagcaacccc ttacatcttt
2221 accagctcag ccaacagcac agtctacaag ccagctgcag gttcaagctc taactcagca
2281 acaacaatcc cctacaaaag ctgtgccggc tttggggaaa agcccgcctc accactctgg
2341 attccagcag tatcaacagg cagatgcctc caaacagctg tggaatcccc ctcaggttca
2401 aggcccatta gggaaaatta tgcctgtgaa acagccctac taccttcaga cccaagaccc
2461 cataaaactg tttgagccgt cattgcaacc tcctgtaatg cagcagcagc ctctagaaaa
2521 aaaaatgaag ccttttccca tggagccata taaccataat ccctcagaag tcaaggtccc
2581 agaattctac tgggattctt cctacagcat ggctgataac agatctgtaa tggcacagca
2641 agcaaacata gaccgcaggg gcaaacggtc accaggaatc ttccgtccag agcaggatcc
2701 tgtacccaga atgccgtttg aggaccccaa gagctcccct ctgcttcctc cggacctgtt
2761 aaagagtctg gctgccttgg aggaagagga agagctgatt ttttctaaca ctcctgatct
2821 ttacccggct ctgctggggc ctctcgcctc tcttcctgga cgaagccttt ttaaatcctt
2881 attggagaag ccctcagagc tcatgtcaca ttcatcctct ttcctgtccc tcaccggatt
2941 ctctctcaat caggaaagat acccaaataa tagtatgttc aatgaggtat atgggaaaaa
3001 cctgacatcc agctccaaag cagaactcag tccctcaatg gccccccagg aaacatctct
3061 gtattccctt tttgaaggga ctccgtggtc tccatcactt cctgccagtt cagatcattc
3121 aacaccagcc agccagtctc ctcattcctc taacccaagc agcctaccca gctctcctcc
3181 aacacacaac cataattctg ttccattctc caattttgga cccattggga ctccagataa
3241 cagggataga aggactgcag atcggtggaa aactgataag ccagccatgg gtgggtttgg
3301 cattgattat ctctcagcaa cgtcatcctc tgagagcagt tggcatcagg ccagcactcc
3361 gagtggcacc tggacaggcc atggcccttc catggaggat tcctctgctg tcctcatgga
3421 aagcctaaag aagcaacagc atggggtcca gcagttgggg cccaaaagac agtctgaaga
3481 ggaaggaagc agcagtatct gcgtagccca cagagggccc aggcccctgc ccagctgcag
3541 tctcccagcc tccactttca gagtgaaatt caaggcagca cggacatgtg cccatcaggc
3601 acagaagaaa acacgacgtc gtccattttg gaagagacga aagaaaggaa aataaactct
3661 ttttatgata tttattagga ggaaagagga ctgaaaatgt tcttgtgtag aaacagaagg
3721 acagcatttc tgttagtcat ttcctggaaa agtaatattt taaggggaaa ttatggaaac
3781 aatctaattg ttcaattgct gtgctagtgg tagggtttat tttctgggag gtctctcctt
3841 tgtgtgtctg tatgtttgtg tacacacacg tgcccatctg ctgtcccaga ggggaggggt
3901 tgtgtgtgcg agtgtatgga gttagtgtgg aacttaagag ctggaagaca gctgtagagc
3961 aaagcacatc caggagcccc agttgtcact gcagtctggg caaccccagc aatgaaaagg
4021 ggtgagataa cgctcattgc tcttcagaga gagtggttgg agcccccccc gccccgtatg
4081 cttacattat tgctctttta gtttgacatg gtgtttgggt tttgtttttt tgaaaggtct
4141 gaaaaggtga agccccctac ccaatggcaa tatgaaacct tttgtgcttc tcttcagccc
4201 cttccctgtg tccacctttc tctcctcttc ccaagccttt ttcctactac ctttacccag
4261 tttgtgtgtt tgagctctgc attcaggcag ctgcaacatt ccagtgtttg aactgtcact
4321 gattcttgcg ccctagacaa gctaaccagg tttaccatct cactcccagt aatacccagc
4381 tcctatctaa agccccattc tgcatgagaa tttggtgttt ggaatgtttt ctgactcttg
4441 gggcgggatt cctcgcctta tcatcctcac tgtggagtaa tgagggggag gagaatcttt
4501 atcagaaact ggttttgtgt agtaaacttt cttttgtggt tttttgtttt gttttctggg
4561 ttttgttttt tgtttttgtc tgtgcaagac ctgcagctgc tgaaaatcag ctttgccttt
4621 aattaaacca tgttctctcc aaaaaaaaaa aaaaaa
//