LOCUS BC035802 1074 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens granzyme K (granzyme 3; tryptase II), mRNA (cDNA clone
MGC:46219 IMAGE:5748080), complete cds.
ACCESSION BC035802
VERSION BC035802.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1074)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1074)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (31-JUL-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 79 Row: l Column: 3
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4504234.
FEATURES Location/Qualifiers
source 1..1074
/db_xref="H-InvDB:HIT000051515"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:46219 IMAGE:5748080"
/tissue_type="Pancreas, Spleen, adult pooled"
/clone_lib="NIH_MGC_120"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1074
/gene="GZMK"
/gene_synonym="TRYP2"
/db_xref="GeneID:3003"
/db_xref="HGNC:HGNC:4711"
/db_xref="MIM:600784"
CDS 45..839
/gene="GZMK"
/gene_synonym="TRYP2"
/codon_start=1
/product="granzyme K (granzyme 3; tryptase II)"
/protein_id="AAH35802.1"
/db_xref="GeneID:3003"
/db_xref="HGNC:HGNC:4711"
/db_xref="MIM:600784"
/translation="MTKFSSFSLFFLIVGAYMTHVCFNMEIIGGKEVSPHSRPFMASI
QYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAHSLSKNEASKQTLEIKKF
IPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSKTSLRSGTKCKVTGWGATDPD
SLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDAKGQKDSCKGDSGGPL
ICKGVFHAIVSGGHECGVATKPGIYTLLTKKYQTWIKSNLVPPHTN"
BASE COUNT 330 a 233 c 205 g 306 t
ORIGIN
1 gatcaacaca tttcatctgg gcttcttaaa tctaaatctt taaaatgact aagttttctt
61 ccttttctct gtttttccta atagttgggg cttatatgac tcatgtgtgt ttcaatatgg
121 aaattattgg agggaaagaa gtgtcacctc attccaggcc atttatggcc tccatccagt
181 atggcggaca tcacgtttgt ggaggtgttc tgattgatcc acagtgggtg ctgacagcag
241 cccactgcca atatcggttt accaaaggcc agtctcccac tgtggtttta ggcgcacact
301 ctctctcaaa gaatgaggcc tccaaacaaa cactggagat caaaaaattt ataccattct
361 caagagttac atcagatcct caatcaaatg atatcatgct ggttaagctt caaacagccg
421 caaaactcaa taaacatgtc aagatgctcc acataagatc caaaacctct cttagatctg
481 gaaccaaatg caaggttact ggctggggag ccaccgatcc agattcatta agaccttctg
541 acaccctgcg agaagtcact gttactgtcc taagtcgaaa actttgcaac agccaaagtt
601 actacaacgg cgaccctttt atcaccaaag acatggtctg tgcaggagat gccaaaggcc
661 agaaggattc ctgtaagggt gactcagggg gccccttgat ctgtaaaggt gtcttccacg
721 ctatagtctc tggaggtcat gaatgtggtg ttgccacaaa gcctggaatc tacaccctgt
781 taaccaagaa ataccagact tggatcaaaa gcaaccttgt cccgcctcat acaaattaag
841 ttacaaataa ttttattgga tgcacttgct tcttttttcc taatatgctc gcaggttaga
901 gttgggtgta agtaaagcag agcacatatg gggtccattt ttgcacttgt aagtcatttt
961 attaaggaat caagttcttt ttcacttgta tcactgatgt atttctacca tgctggtttt
1021 attctaaata aaatttagaa gactcaaaaa aaaaaaaaaa aaaaaaaaaa aaaa
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