LOCUS BC035407 1760 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens interleukin 3 receptor, alpha (low affinity), mRNA
(cDNA clone MGC:34174 IMAGE:5167281), complete cds.
ACCESSION BC035407
VERSION BC035407.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1760)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1760)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (31-JUL-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 52 Row: o Column: 22
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 28416950.
FEATURES Location/Qualifiers
source 1..1760
/db_xref="H-InvDB:HIT000051392_04"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:34174 IMAGE:5167281"
/tissue_type="Brain, adult medulla"
/clone_lib="NIH_MGC_119"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1760
/gene="IL3RA"
/gene_synonym="CD123"
/gene_synonym="hIL-3Ra"
/gene_synonym="IL3R"
/gene_synonym="IL3RAY"
/gene_synonym="IL3RX"
/gene_synonym="IL3RY"
/gene_synonym="MGC34174"
/db_xref="GeneID:3563"
/db_xref="HGNC:HGNC:6012"
/db_xref="MIM:430000"
CDS 350..1486
/gene="IL3RA"
/gene_synonym="CD123"
/gene_synonym="hIL-3Ra"
/gene_synonym="IL3R"
/gene_synonym="IL3RAY"
/gene_synonym="IL3RX"
/gene_synonym="IL3RY"
/gene_synonym="MGC34174"
/codon_start=1
/product="interleukin 3 receptor, alpha (low affinity)"
/protein_id="AAH35407.1"
/db_xref="GeneID:3563"
/db_xref="HGNC:HGNC:6012"
/db_xref="MIM:430000"
/translation="MVLLWLTLLLIALPCLLQTKEDPNPPITNLRMKAKAQQLTWDLN
RNVTDIECVKDADYSMPAVNNSYCQFGAISLCEVTNYTVRVANPPFSTWILFPENSGK
PWAGAENLTCWIHDVDFLSCSWAVGPGAPADVQYDLYLNVANRRQQYECLHYKTDAQG
TRIGCRFDDISRLSSGSQSSHILVRGRSAAFGIPCTDKFVVFSQIEILTPPNMTAKCN
KTHSFMHWKMRSHFNRKFRYELQIQKRMQPVITEQVRDRTSFQLLNPGTYTVQIRARE
RVYEFLSAWSTPQRFECDQEEGANTRAWRTSLLIALGTLLALVCVFVICRRYLVMQRL
FPRIPHMKDPIGDSFQNDKLVVWEAGKAGLEECLVTEVQVVQKT"
BASE COUNT 461 a 456 c 457 g 386 t
ORIGIN
1 gtcaggttca tggttacgaa gctgctgacc ccaggatccc agcccgtggg agagaagggg
61 gtctctgaca gcccccaccc ctccccactg ccagatcctt attgggtctg agtttcaggg
121 gtggggcccc agctggaggt tataaaacag ctcaatcggg gagtacaacc ttcggtttct
181 cttcggggaa agctgctttc agcgcacacg ggaagatatc agaaacatcc taggatcagg
241 acaccccaga tcttctcaac tggaaccacg aaggctgttt cttccacaca gcactttgat
301 ctccatttaa gcaggcacct ctgtcctgcg ttccggagct gcgttcccga tggtcctcct
361 ttggctcacg ctgctcctga tcgccctgcc ctgtctcctg caaacgaagg aagatccaaa
421 cccaccaatc acgaacctaa ggatgaaagc aaaggctcag cagttgacct gggaccttaa
481 cagaaatgtg accgatatcg agtgtgttaa agacgccgac tattctatgc cggcagtgaa
541 caatagctat tgccagtttg gagcaatttc cttatgtgaa gtgaccaact acaccgtccg
601 agtggccaac ccaccattct ccacgtggat cctcttccct gagaacagtg ggaagccttg
661 ggcaggtgcg gagaatctga cctgctggat tcatgacgtg gatttcttga gctgcagctg
721 ggcggtaggc ccgggggccc ccgcggacgt ccagtacgac ctgtacttga acgttgccaa
781 caggcgtcaa cagtacgagt gtcttcacta caaaacggat gctcagggaa cacgtatcgg
841 gtgtcgtttc gatgacatct ctcgactctc cagcggttct caaagttccc acatcctggt
901 gcggggcagg agcgcagcct tcggtatccc ctgcacagat aagtttgtcg tcttttcaca
961 gattgagata ttaactccac ccaacatgac tgcaaagtgt aataagacac attcctttat
1021 gcactggaaa atgagaagtc atttcaatcg caaatttcgc tatgagcttc agatacaaaa
1081 gagaatgcag cctgtaatca cagaacaggt cagagacaga acctccttcc agctactcaa
1141 tcctggaacg tacacagtac aaataagagc ccgggaaaga gtgtatgaat tcttgagcgc
1201 ctggagcacc ccccagcgct tcgagtgcga ccaggaggag ggcgcaaaca cacgtgcctg
1261 gcggacgtcg ctgctgatcg cgctggggac gctgctggcc ctggtctgtg tcttcgtgat
1321 ctgcagaagg tatctggtga tgcagagact ctttccccgc atccctcaca tgaaagaccc
1381 catcggtgac agcttccaaa acgacaagct ggtggtctgg gaggcgggca aagccggcct
1441 ggaggagtgt ctggtgactg aagtacaggt cgtgcagaaa acttgagact ggggttcagg
1501 gcttgtgggg gtctgcctca atctccctgg ccgggccagg cgcctgcaca gactggctgc
1561 tggacctgcg cacgcagccc aggaatggac attcctaacg ggtggtgggc atgggagatg
1621 cctgtgtaat ttcgtccgaa gctgccagga agaagaacag aactttgtgt gtttatttca
1681 tgataaagtg attttttttt ttttaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1741 aaaaaaaaaa aaaaaaaaaa
//