LOCUS BC033824 1917 bp mRNA linear HUM 30-SEP-2003
DEFINITION Homo sapiens numb homolog (Drosophila), mRNA (cDNA clone
IMAGE:5217787), complete cds.
ACCESSION BC033824
VERSION BC033824.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1917)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1917)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (02-JUL-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 68 Row: p Column: 13
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 20070355
This clone has the following problem: The cds is short compared to
the longest cds in the locus.
FEATURES Location/Qualifiers
source 1..1917
/db_xref="H-InvDB:HIT000041982"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:5217787"
/tissue_type="Blood, adult leukocytes"
/clone_lib="NIH_MGC_118"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1917
/gene="NUMB"
/gene_synonym="S171"
/db_xref="GeneID:8650"
/db_xref="MIM:603728"
CDS 111..518
/gene="NUMB"
/gene_synonym="S171"
/codon_start=1
/product="NUMB protein"
/protein_id="AAH33824.1"
/db_xref="GeneID:8650"
/db_xref="MIM:603728"
/translation="MPYPAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQ
TFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASADRHTEVPTGTCPVDPFEA
QWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL"
BASE COUNT 569 a 412 c 390 g 546 t
ORIGIN
1 cacctttcca agggaatgca ttcctcacct ctcagcctgt gccagtgggt gtggtcccag
61 ccctgcaacc agcctttgtc cctgcccagt cctatcctgt ggccaatgga atgccctatc
121 cagcccctaa tgtgcctgtg gtgggcatca ctccctccca gatggtggcc aacgtatttg
181 gcactgcagg ccaccctcag gctgcccatc cccatcagtc acccagcctg gtcaggcagc
241 agacattccc tcactacgag gcaagcagtg ctaccaccag tcccttcttt aagcctcctg
301 ctcagcacct caacggttct gcagctttca atggtgtaga tgatggcagg ttggcctcag
361 cagacaggca tacagaggtt cctacaggca cctgcccagt ggatcctttt gaagcccagt
421 gggctgcatt agaaaataag tccaagcagc gtactaatcc ctcccctacc aaccctttct
481 ccagtgactt acagaagacg tttgaaattg aactttaagc aatcattatg gctatgtatc
541 ttgtccatac cagacaggga gcagggggta gcggtcaaag gagcaaaaca gactttgtct
601 cctgattagt actcttttca ctaatcccaa aggtcccaag gaacaagtcc aggcccagag
661 tactgtgagg ggtgattttg aaagacatgg gaaaaagcat tcctagagaa aagctgcctt
721 gcaattaggc taaagaagtc aaggaaatgt tgctttctgt actccctctt cccttacccc
781 cttacaaatc tctggcaaca gagaggcaaa gtatctgaac aagaatctat attccaagca
841 catttactga aatgtaaaac acaacaggaa gcaaagcaat ctccctttgt ttttcaggcc
901 attcacctgc ctcctgtcag tagtggcctg tattagagat caagaagagt ggtttgtgct
961 caggctgggg aacagagagg cacgctatgc tgccagaatt cccaggaggg catatcagca
1021 actgcccagc agagctatat tttgggggag aagttgagct tccattttga gtaacagaat
1081 aaatattata tatatcaaaa gccaaaatct ttatttttat gcatttagaa tattttaaat
1141 agttctcaga tattaagaag ttgtatgagt tgtaagtaat cttgccaaag gtaaaggggc
1201 tagttgtaag aaattgtaca taagattgat ttatcattga tgcctactga aataaaaaga
1261 ggaaaggctg gaagctgcag acaggatccc tagcttgttt tctgtcagtc attcattgta
1321 agtagcacat tgcaacaaca atcatgctta tgaccaatac agtcactagg ttgtagtttt
1381 ttttaaataa aggaaaagca gtattgtcct ggttttaaac ctatgatgga attctaatgt
1441 cattatttta atggaatcaa tcgaaatatg ctctatagag aatatatctt ttatatattg
1501 ctgcagtttc cttatgttaa tcttttaaca ctaaggtaac atgacataat cataccatag
1561 aagggaacac aggttaccat attggtttgt aatatgggtc ttggtgggtt ttgttttatc
1621 ctttaaattt tgttcccatg agttttgtgg ggatggggat tctggtttta ttagctttgt
1681 gtgtgtcctc ttcccccaaa cccccttttg gtgagaacat ccccttgaca gttgcagcct
1741 cttgacctcg gataacaata agagagctca tctcattttt acttttgaac gttggcctta
1801 caatcaaatg taagttatat atatttgtac tgatgaaaat ttataatctg ctttaacaaa
1861 aataaatgtt catggtagaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa
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