LOCUS BC033651 3595 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens toll-like receptor 7, mRNA (cDNA clone MGC:45096
IMAGE:5582912), complete cds.
ACCESSION BC033651
VERSION BC033651.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3595)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3595)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-JUL-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 69 Row: p Column: 16
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 67944638.
FEATURES Location/Qualifiers
source 1..3595
/db_xref="H-InvDB:HIT000041887"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:45096 IMAGE:5582912"
/tissue_type="Testis, embryonal carcinoma"
/clone_lib="NIH_MGC_92"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3595
/gene="TLR7"
/db_xref="GeneID:51284"
/db_xref="HGNC:HGNC:15631"
/db_xref="MIM:300365"
CDS 151..3300
/gene="TLR7"
/codon_start=1
/product="toll-like receptor 7"
/protein_id="AAH33651.1"
/db_xref="GeneID:51284"
/db_xref="HGNC:HGNC:15631"
/db_xref="MIM:300365"
/translation="MVFPMWTLKRQILILFNIILISKLLGARWFPKTLPCDVTLDVPK
NHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLDHLVEIDFRCNCVP
IPLGSKNNMCIKRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQGLPPSLQLLSLEANNI
FSIRKENLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNNVTA
VPTVLPSTLTELYLYNNMIAKIQEDDFNNLNQLQILDLSGNCPRCYNAPFPCAPCKNN
SPLQIPVNAFDALTELKVLRLHSNSLQHVPPRWFKNINKLQELDLSQNFLAKEIGDAK
FLHFLPSLIQLDLSFNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFNLSP
LHNLQNLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKISPSGDSSEVGFCSNART
SVESYEPQVLEQLHYFRYDKYARSCRFKNKEASFMSVNESCYKYGQTLDLSKNSIFFV
KSSDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELH
KLEVLDISSNSHYFQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTL
EFRGNHLDVLWREGDNRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSL
AKNGLKSFSWKKLQCLKNLETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTK
YFLQDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLKMLLLHHNRFLCTCDAVWFVWWV
NHTEVTIPYLATDVTCVGPGAHKGQSVISLDLYTCELDLTNLILFSLSISVSLFLMVM
MTASHLYFWDVWYIYHFCKAKIKGYQRLISPDCCYDAFIVYDTKDPAVTEWVLAELVA
KLEDPREKHFNLCLEERDWLPGQPVLENLSQSIQLSKKTVFVMTDKYAKTENFKIAFY
LSHQRLMDEKVDVIILIFLEKPFQKSKFLQLRKRLCGSSVLEWPTNPQAHPYFWQCLK
NALATDNHVAYSQVFKETV"
BASE COUNT 1090 a 802 c 677 g 1026 t
ORIGIN
1 ccacgcgtcc ggaagactcc agatatagga tcactccatg ccatcaagaa agttgatgct
61 attgggccca tctcaagctg atcttggcac ctctcatgct ctgctctctt caaccagacc
121 tctacattcc attttggaag aagactaaaa atggtgtttc caatgtggac actgaagaga
181 caaattctta tcctttttaa cataatccta atttccaaac tccttggggc tagatggttt
241 cctaaaactc tgccctgtga tgtcactctg gatgttccaa agaaccatgt gatcgtggac
301 tgcacagaca agcatttgac agaaattcct ggaggtattc ccacgaacac cacgaacctc
361 accctcacca ttaaccacat accagacatc tccccagcgt cctttcacag actggaccat
421 ctggtagaga tcgatttcag atgcaactgt gtacctattc cactggggtc aaaaaacaac
481 atgtgcatca agaggctgca gattaaaccc agaagcttta gtggactcac ttatttaaaa
541 tccctttacc tggatggaaa ccagctacta gagataccgc agggcctccc gcctagctta
601 cagcttctca gccttgaggc caacaacatc ttttccatca gaaaagagaa tctaacagaa
661 ctggccaaca tagaaatact ctacctgggc caaaactgtt attatcgaaa tccttgttat
721 gtttcatatt caatagagaa agatgccttc ctaaacttga caaagttaaa agtgctctcc
781 ctgaaagata acaatgtcac agccgtccct actgttttgc catctacttt aacagaacta
841 tatctctaca acaacatgat tgcaaaaatc caagaagatg attttaataa cctcaaccaa
901 ttacaaattc ttgacctaag tggaaattgc cctcgttgtt ataatgcccc atttccttgt
961 gcgccgtgta aaaataattc tcccctacag atccctgtaa atgcttttga tgcgctgaca
1021 gaattaaaag ttttacgtct acacagtaac tctcttcagc atgtgccccc aagatggttt
1081 aagaacatca acaaactcca ggaactggat ctgtcccaaa acttcttggc caaagaaatt
1141 ggggatgcta aatttctgca ttttctcccc agcctcatcc aattggatct gtctttcaat
1201 tttgaacttc aggtctatcg tgcatctatg aatctatcac aagcattttc ttcactgaaa
1261 agcctgaaaa ttctgcggat cagaggatat gtctttaaag agttgaaaag ctttaacctc
1321 tcgccattac ataatcttca aaatcttgaa gttcttgatc ttggcactaa ctttataaaa
1381 attgctaacc tcagcatgtt taaacaattt aaaagactga aagtcataga tctttcagtg
1441 aataaaatat caccttcagg agattcaagt gaagttggct tctgctcaaa tgccagaact
1501 tctgtagaaa gttatgaacc ccaggtcctg gaacaattac attatttcag atatgataag
1561 tatgcaagga gttgcagatt caaaaacaaa gaggcttctt tcatgtctgt taatgaaagc
1621 tgctacaagt atgggcagac cttggatcta agtaaaaata gtatattttt tgtcaagtcc
1681 tctgattttc agcatctttc tttcctcaaa tgcctgaatc tgtcaggaaa tctcattagc
1741 caaactctta atggcagtga attccaacct ttagcagagc tgagatattt ggacttctcc
1801 aacaaccggc ttgatttact ccattcaaca gcatttgaag agcttcacaa actggaagtt
1861 ctggatataa gcagtaatag ccattatttt caatcagaag gaattactca tatgctaaac
1921 tttaccaaga acctaaaggt tctgcagaaa ctgatgatga acgacaatga catctcttcc
1981 tccaccagca ggaccatgga gagtgagtct cttagaactc tggaattcag aggaaatcac
2041 ttagatgttt tatggagaga aggtgataac agatacttac aattattcaa gaatctgcta
2101 aaattagagg aattagacat ctctaaaaat tccctaagtt tcttgccttc tggagttttt
2161 gatggtatgc ctccaaatct aaagaatctc tctttggcca aaaatgggct caaatctttc
2221 agttggaaga aactccagtg tctaaagaac ctggaaactt tggacctcag ccacaaccaa
2281 ctgaccactg tccctgagag attatccaac tgttccagaa gcctcaagaa tctgattctt
2341 aagaataatc aaatcaggag tctgacgaag tattttctac aagatgcctt ccagttgcga
2401 tatctggatc tcagctcaaa taaaatccag atgatccaaa agaccagctt cccagaaaat
2461 gtcctcaaca atctgaagat gttgcttttg catcataatc ggtttctgtg cacctgtgat
2521 gctgtgtggt ttgtctggtg ggttaaccat acagaggtga ctattcctta cctggccaca
2581 gatgtgactt gtgtggggcc aggagcacac aagggccaaa gtgtgatctc cctggatctg
2641 tacacctgtg agttagatct gactaacctg attctgttct cactttccat atctgtatct
2701 ctctttctca tggtgatgat gacagcaagt cacctctatt tctgggatgt gtggtatatt
2761 taccatttct gtaaggccaa gataaagggg tatcagcgtc taatatcacc agactgttgc
2821 tatgatgctt ttattgtgta tgacactaaa gacccagctg tgaccgagtg ggttttggct
2881 gagctggtgg ccaaactgga agacccaaga gagaaacatt ttaatttatg tctcgaggaa
2941 agggactggt taccagggca gccagttctg gaaaaccttt cccagagcat acagcttagc
3001 aaaaagacag tgtttgtgat gacagacaag tatgcaaaga ctgaaaattt taagatagca
3061 ttttacttgt cccatcagag gctcatggat gaaaaagttg atgtgattat cttgatattt
3121 cttgagaagc cctttcagaa gtccaagttc ctccagctcc ggaaaaggct ctgtgggagt
3181 tctgtccttg agtggccaac aaacccgcaa gctcacccat acttctggca gtgtctaaag
3241 aacgccctgg ccacagacaa tcatgtggcc tatagtcagg tgttcaagga aacggtctag
3301 cccttctttg caaaacacaa ctgcctagtt taccaaggag aggcctggct gtttaaattg
3361 ttttcatata tatcacacca aaagcgtgtt ttgaaattct tcaagaaatg agattgccca
3421 tatttcaggg gagccaccaa cgtctgtcac aggagttgga aagatggggt ttatataatg
3481 catcaagtct tctttcttat ctctctgtgt ctctatttgc acttgagtct ctcacctcag
3541 ctcctgtaaa agagtggcaa gtaaaaaaca tggggctctg aaaaaaaaaa aaaaa
//