LOCUS BC033625 1400 bp mRNA linear HUM 27-OCT-2006
DEFINITION Homo sapiens G protein-coupled bile acid receptor 1, mRNA (cDNA
clone MGC:40597 IMAGE:5221127), complete cds.
ACCESSION BC033625
VERSION BC033625.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1400)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1400)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-JUL-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 64 Row: n Column: 14
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 24850108.
FEATURES Location/Qualifiers
source 1..1400
/db_xref="H-InvDB:HIT000041871"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:40597 IMAGE:5221127"
/tissue_type="Pancreas, Spleen, adult pooled"
/clone_lib="NIH_MGC_120"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1400
/gene="GPBAR1"
/gene_synonym="BG37"
/gene_synonym="GPCR"
/gene_synonym="GPCR19"
/gene_synonym="GPR131"
/gene_synonym="M-BAR"
/gene_synonym="MGC40597"
/gene_synonym="TGR5"
/db_xref="GeneID:151306"
/db_xref="HGNC:HGNC:19680"
/db_xref="MIM:610147"
CDS 232..1224
/gene="GPBAR1"
/gene_synonym="BG37"
/gene_synonym="GPCR"
/gene_synonym="GPCR19"
/gene_synonym="GPR131"
/gene_synonym="M-BAR"
/gene_synonym="MGC40597"
/gene_synonym="TGR5"
/codon_start=1
/product="G protein-coupled bile acid receptor 1"
/protein_id="AAH33625.1"
/db_xref="GeneID:151306"
/db_xref="HGNC:HGNC:19680"
/db_xref="MIM:610147"
/translation="MTPNSTGEVPSPIPKGALGLSLALASLIITANLLLALGIAWDRR
LRSPPAGCFFLSLLLAGLLTGLALPTLPGLWNQSRRGYWSCLLVYLAPNFSFLSLLAN
LLLVHGERYMAVLRPLQPPGSIRLALLLTWAGPLLFASLPALGWNHWTPGANCSSQAI
FPAPYLYLEVYGLLLPAVGAAAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARAL
TWRQARAQAGAMLLFGLCWGPYVATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAV
PVAMGLGDQRYTAPWRAAAQRCLQGLWGRASRDSPGPSIAYHPSSQSSVDLDLN"
BASE COUNT 243 a 504 c 390 g 263 t
ORIGIN
1 gcagagcctg ggtaggagag cctggccccg ctgtccccac tgggtggaga caccatgcac
61 ttggtccttg tgctcttcag ccaggacacc agacatggtc caaaccgctg cagggctggc
121 tgcagcaact ccctgacact caggaaggcc caggctgggc aggcaatacc tgctcccaac
181 agccatgcat gccggctgcc gctccaggac tcccctgtcc ccaggaccaa gatgacgccc
241 aacagcactg gcgaggtgcc cagccccatt cccaaggggg ctttggggct ctccctggcc
301 ctggcaagcc tcatcatcac cgcgaacctg ctcctagccc tgggcatcgc ctgggaccgc
361 cgcctgcgca gcccacctgc tggctgcttc ttcctgagcc tactgctggc tgggctgctc
421 acgggtctgg cattgcccac attgccaggg ctgtggaacc agagtcgccg gggttactgg
481 tcctgcctcc tcgtctactt ggctcccaac ttctccttcc tctccctgct tgccaacctc
541 ttgctggtgc acggggagcg ctacatggca gtcctgaggc cactccagcc ccctgggagc
601 attcggctgg ccctgctcct cacctgggct ggtcccctgc tctttgccag tctgcccgct
661 ctggggtgga accactggac ccctggtgcc aactgcagct cccaggctat cttcccagcc
721 ccctacctgt acctcgaagt ctatgggctc ctgctgcccg ccgtgggtgc tgctgccttc
781 ctctctgtcc gcgtgctggc cactgcccac cgccagctgc aggacatctg ccggctggag
841 cgggcagtgt gccgcgatga gccctccgcc ctggcccggg cccttacctg gaggcaggca
901 agggcacagg ctggagccat gctgctcttc gggctgtgct gggggcccta cgtggccaca
961 ctgctcctct cagtcctggc ctatgagcag cgcccgccac tggggcctgg gacactgttg
1021 tccctcctct ccctaggaag tgccagtgca gcggcagtgc ccgtagccat ggggctgggc
1081 gatcagcgct acacagcccc ctggagggca gccgcccaaa ggtgcctgca ggggctgtgg
1141 ggaagagcct cccgggacag tcccggcccc agcattgcct accacccaag cagccaaagc
1201 agtgtcgacc tggacttgaa ctaaaggaag ggcctctgct gactcctacc agagcatccg
1261 tccagctcag ccatccagcc tgtctctact gggccccact tctctggatc agagaccctg
1321 cctctgtttg accccgcact gactgaataa agctcctctg gccgttaaaa aaaaaaaaaa
1381 aaaaaaaaaa aaaaaaaaaa
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