LOCUS BC033450 4748 bp mRNA linear HUM 27-OCT-2006
DEFINITION Homo sapiens transmembrane protein 181, mRNA (cDNA clone
IMAGE:3874410), partial cds.
ACCESSION BC033450
VERSION BC033450.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4748)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4748)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (26-JUN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 13 Row: o Column: 8
This clone was selected for full length sequencing because it
passed the following selection criteria: Hexamer frequency ORF
analysis
This clone grew slowly and was rescued by PCR.
FEATURES Location/Qualifiers
source 1..4748
/db_xref="H-InvDB:HIT000093095"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:3874410"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene <1..4748
/gene="TMEM181"
/db_xref="GeneID:57583"
/db_xref="HGNC:HGNC:20958"
CDS <1..1573
/gene="TMEM181"
/codon_start=2
/product="TMEM181 protein"
/protein_id="AAH33450.1"
/db_xref="GeneID:57583"
/db_xref="HGNC:HGNC:20958"
/translation="LPSPGPAQRASSPIPSAGRREGAQAATQRVERRDRDPGGCAAWT
PSTLPLSPRSAASSSTCAGGCGKRTASSRRTSRPSRMTATTGPKVIQTSAANFSLNNS
KKLKPIQILSNPLSTYNQQLWLTCVVELDQSKETSIKTSFPMTVKVDGVAQDGTTMYI
HNKVHNRTRTLTCAGKCAEIIVAHLGYLNYTQYTVIVGFEHLKLPIKGMNFTWKTYNP
AFSRLEIWFRFFFVVLTFIVTCLFAHSLRKFSMRDWGIEQKWMSVLLPLLLLYNDPFF
PLSFLVNSWLPGMLDDLFQSMFLCALLLFWLCVYHGIRVQGERKCLTFYLPKFFIVGL
LWLASVTLGIWQTVNELHDPMYQYRVDTGNFQGMKVFFMVVAAVYILYLLFLIVRACS
ELRHMPYVDLRLKFLTALTFVVLVISIAILYLRFGAQVLQDNFVAELSTHYQNSAEFL
SFYGLLNFYLYTLAFVYSPSKNALYESQLKDNPAFSMLNDSDDDVIYGSHYEEMPLQN
GQAIRAKYKEESDSD"
BASE COUNT 1313 a 946 c 1060 g 1429 t
ORIGIN
1 cctgccttct cccggtcccg cccagcgcgc cagcagcccg atccccagtg ctgggagaag
61 agagggggcg caggcggcga cacaaagggt ggagcggcgg gaccgggacc cgggaggctg
121 cgcggcatgg acgccgagta ccctgccttt gagcccccgc tctgcagcga gctcaagcac
181 ctgtgccggc ggctgcggga agcgtaccgc gagctcaagg aggacctcac gcccttcaag
241 gatgaccgct actacaggac ctaaagtgat ccagacttct gcggctaatt tttcactaaa
301 taatagcaaa aagctaaagc caattcaaat actttcaaat ccactgtcta catacaatca
361 gcaactatgg ctgacatgtg ttgttgagtt ggatcaatca aaagaaactt ctattaagac
421 aagctttccc atgactgtta aagtcgatgg tgtagctcaa gatggaacca cgatgtacat
481 tcataacaaa gttcacaacc ggacaaggac cctcacatgt gcagggaaat gtgcggagat
541 tattgtggct caccttggct acctgaacta cactcagtat acagtgatag tgggatttga
601 acacctgaag ctccccatca agggaatgaa cttcacatgg aagacttata accctgcctt
661 ctcccggttg gaaatctggt tccggttttt ctttgtggtg ctcaccttca tcgtcacttg
721 cctgtttgcg cattccctcc ggaaattttc catgagagac tggggcatcg agcagaagtg
781 gatgtctgtt ctcctgcctc tgctgctact ttacaatgat ccgttcttcc ccctctcctt
841 cctggtcaac agctggctcc cagggatgct ggatgacctc tttcagtcca tgttcctgtg
901 cgccctgctg ctcttctggc tgtgcgtgta ccacgggatt cgtgtccagg gagaaagaaa
961 gtgtttaact ttctatttgc ctaaattctt cattgttgga ctattgtggt tggcttctgt
1021 tacgctagga atatggcaaa cagttaacga attacatgat ccaatgtacc agtatcgagt
1081 tgataccgga aattttcagg gaatgaaggt cttcttcatg gtggtggcag cggtgtacat
1141 tctgtacctc ttgttcttga tagtgcgggc gtgttccgag ctacgtcaca tgccttatgt
1201 ggatctcagg ttgaaatttt tgactgcatt gactttcgta gtacttgtca ttagcatcgc
1261 catcctttat ttgagatttg gggcgcaagt actacaagac aattttgtag cagagctgtc
1321 aactcactac cagaattcag ccgagttctt atctttctat ggcctgttga acttctatct
1381 ctacaccttg gcctttgtat attctccatc gaagaatgcc ctctatgagt cccagctgaa
1441 agacaatcct gccttctcca tgctgaatga ctcggatgat gatgtgattt atgggagtca
1501 ctatgaggaa atgccgctgc agaacggcca ggccatccgg gccaagtaca aggaggagtc
1561 agatagtgac tgagccccgg ccagcccagc gaggcgacaa gatgcctgga tgctttcccc
1621 ggtgaccgtc tgctgacctt cccctgttat attcagattt ttcttacaag cagagatttc
1681 ctgttcattt gtttacatat ttttttaaag gaaaaccaaa actgagggta aatttaaatg
1741 tttagccaaa tttattgtca tggtggctac gagaagaggc attgataaca agtttcaaca
1801 gccaaatcct tttttacaga gatttcagat gagcgtgttt tcagtgatga ggaaatttca
1861 cgtttttagt acagtgaatt atgtactttt ttttcctgta atcattcact gattccaagt
1921 tcacgggcag cctgtgacta ggtcctcagc gtgacagcat caccctcttt cttccctttt
1981 ccatggtact gttttgtgac cctttaaact caaagggaag ccttatctgt ggctgcttca
2041 gggcagtcct tcctcgttga gtggccagtg ccctgggtaa ccaggtggct gaagtgattg
2101 gtcagttatg tggactgcgt tttgtgcagt gtgtgagtta tgactcatcg ggaatgggag
2161 atgctggggt tccaaccctt cacgtcacca aaggggaagt aatagtgtgg agttctgagg
2221 agggtttgat aagttgaata aggaaaggct aagataattt acaggttacc aactcatgtg
2281 gggaaggtct tactgccatg gtgcttttca ggggcctgtg tgtacacaca tgattaaatg
2341 gatttgcctg tgggaggtat gggcaggaga ggaaccctta ccattccagt aaatagcagt
2401 ttctgcaatt ctgttgaata tgaaatgcca tagagcttta tttatttatg taagtaaaag
2461 ctaaatgagg ggccaggtgc agtggctcac atctgtaatc tcaacacttt gggaggccaa
2521 ggtgggagga tcacttgagc ccaggagttt gagaccagcc tgggcaacac agggagaccc
2581 cgtctctata aaacatttag aaagttggct gggcatgctg gggcatgccc atagtcccag
2641 ctactcagga ggctgaggtg ggaggattgc ttgagccctg gaggtcaagg ctgcagtgag
2701 ccatgattgc accactgcac tccagcctgg gtgtcagagc gagaacccgt gtcataaata
2761 aataaagcta catgaaagat tgatagaata ttttagatta tttattggcc aaaagttttt
2821 aaaactcata tttggaagca aaatgaaaag caagtaaaat gttttaaatg gttcatggaa
2881 aacgtatttg ggtagaaggc aactcgtgct tccggaaggg gttccctgtc ctccatgtgt
2941 ccacatggcg gtcaggtagg gacgacctgt tctgtaaagt ccttggcact gctgaatctg
3001 tggcatcata gaaggccctg gagcttcccc gttcctttca gtcagggact ccatatagag
3061 tctcatgtgg acgtctcccg tgctttcctc ttgacctcta cagtcacact tctgttaaca
3121 tctggtaact gtgggcaacc tgactgatgc cgtcttggca attgaggtcc agaagatgat
3181 agttccgcaa cgcaagcagt acctactttt tttcttcatc tatgcattga ctctcagatt
3241 accatgcaga gcttcacgtt atcatccacg ttaagtagtg ctaggtagga ccttagagat
3301 gttcatgaga aactatttgt tatgactttc ctttgtatct ttccttttaa tttaaacttt
3361 aatgataatg tacttttaat atggattcta ttcacatttg ttttaaaaac cttgtaaata
3421 tgagtgttta agacaactta ctgcaagggt aattcaagtt tacatgattt ttaaatttgc
3481 aatgatgttt tttttattct gtgtattgaa aaaaattttc tgttaccaaa ttttacaact
3541 tctaataaga ctactataac tttatgtaaa ctgatgaaga tgtgctgatt aacatattct
3601 gtgatatggt ttacaacttt taatcataat tgtccatgat tttggaatgc tgttatttat
3661 cagtaaatgt aaaatatttg aggcatttag ccatacacac actagaactt tttaaaactt
3721 tgtcctatag tgtaattata aactgatgac tattatcttc atacattgag tcttcatgca
3781 tcaatgaaat gaaaaatata ggattattta tttacttttt gtaactaagt gggaaataag
3841 aaaaaaagtt agaaagtact taaggggaaa atcgttctta ctaagtcatg tattttcaac
3901 ttgtcttccc tggtatatca taaataccga catattacat accccatgta aaattttgct
3961 taaactctct agcacttggc atgtagaata tgtaccatag gtatcaggtt aaaacactaa
4021 agtctgccag aaacttttga cagtagcaag aaaattgttg aagaaaaaat aaattattta
4081 ctgagggtag ttatgttaaa gttttgcgaa cttaaagggc tgactttagt tccttcatgg
4141 taatggcttg agtaacatca tctttgggat tttttaaata ctggtccagt ctaggagaac
4201 ctggaagatg accagaggta tttcagtttc cctagggaga gcttcgttat ccatgtggat
4261 gataagtctg cttgatttat tattaaatca ttatagcagt gaagtggtgc cattttctct
4321 ctcttaagcc ccatttgaaa ggctagagaa ggggatatat atactatgtt caaggtttgt
4381 aaggttgtta atgtacataa ttgcagattg caataaaagc ttagatacat tttgtaaacc
4441 caacccacta aatgagcagg ttacaagaca aatgtcacca gcctcaagta ttttatgaac
4501 tatttactga gggtagttat gttaaataga ttataatgtg gtaaattatt tcctgaatcc
4561 tttatcacag gaaaaacaca gaccctcata aaagggataa ttaaaacgga tgtgtctgaa
4621 catttagtga agatgagact taaaacatga aagtgtattt gtgtattttg agggttttag
4681 aaaccggttg ccttagaggt tagacttttg aagaaaaaaa aaaaaaaaaa aaaaaaaaaa
4741 aaaaaaaa
//