LOCUS BC033187 2839 bp mRNA linear HUM 30-JUL-2007
DEFINITION Homo sapiens vav 2 guanine nucleotide exchange factor, mRNA (cDNA
clone IMAGE:4589584), partial cds.
ACCESSION BC033187
VERSION BC033187.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2839)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2839)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (25-JUN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 43 Row: f Column: 5.
FEATURES Location/Qualifiers
source 1..2839
/db_xref="H-InvDB:HIT000259053"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4589584"
/tissue_type="Kidney, renal cell adenocarcinoma"
/clone_lib="NIH_MGC_14"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..2839
/gene="VAV2"
/db_xref="GeneID:7410"
/db_xref="HGNC:HGNC:12658"
/db_xref="MIM:600428"
CDS <1..1111
/gene="VAV2"
/codon_start=2
/product="VAV2 protein"
/protein_id="AAH33187.1"
/db_xref="GeneID:7410"
/db_xref="HGNC:HGNC:12658"
/db_xref="MIM:600428"
/translation="LIHLQGKQGFQFFCKTEDMKRKWMEQFEMAMSNIKPDKANANHH
SFQMYTFDKTTNCKACKMFLRGTFYQGYMCTKCGVGAHKECLEVIPPCKFTSPADLDA
SGAGPGPKMVAMQNYHGNPAPPGKPVLTFQTGDVLELLRGDPESPWWEGRLVQTRKSG
YFPSSSVKPCPVDGRPPISRPPSREIDYTAYPWFAGNMERQQTDNLLKSHASGTYLIR
ERPAEAERFAISIKFNDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQCHSLKESF
KQLDTTLKYPYKSRERSASRASSRSPVFTPRVIGTAVARYNFAARDMRELSLREGDVV
RIYSRIGGDQGWWKGETNGRIGWFPSTYVEEEGIQ"
BASE COUNT 612 a 804 c 858 g 565 t
ORIGIN
1 cctaattcac cttcaaggaa agcagggctt ccagtttttc tgcaaaacag aagatatgaa
61 gaggaagtgg atggagcagt ttgagatggc catgtcaaac atcaagccag acaaagccaa
121 tgccaaccac cacagtttcc agatgtacac gtttgacaag accaccaact gcaaagcctg
181 caaaatgttc ctcaggggca ccttctacca gggatacatg tgtaccaagt gtggcgtcgg
241 ggcacacaag gagtgcctgg aagtgatacc tccctgcaag ttcacttctc ctgcagatct
301 ggacgcctcc ggagcgggac caggtcccaa gatggtggcc atgcagaatt accatggcaa
361 cccagcccct cccgggaagc ctgtgctgac cttccagacg ggcgacgtgc ttgagctgct
421 gaggggcgac cctgagtctc cgtggtggga gggtcgtctg gtacaaacca ggaagtcagg
481 gtatttcccc agctcatctg tgaagccctg ccctgtggat ggaaggccgc ccatcagccg
541 gccgccatcc cgggagatcg actacactgc atacccctgg tttgcaggta acatggagag
601 gcagcagacg gacaacctgc tcaagtccca cgccagcggg acctacctga tcagggagcg
661 gcctgccgag gctgagcgct ttgcaataag catcaagttc aatgatgagg tgaagcacat
721 caaggtggtg gagaaggaca actggatcca catcacagag gccaagaaat tcgacagcct
781 cctggagttg gtggagtact accagtgcca ctcactgaag gagagcttca agcagctgga
841 caccacactc aagtacccct acaagtcccg ggaacgttcg gcctccaggg cctccagccg
901 gtccccagtg ttcacgcccc gcgtcatcgg cacagctgtg gccaggtata actttgccgc
961 ccgagatatg agggagcttt cgctgcggga gggtgacgtg gtgaggatct acagccgcat
1021 cggcggagac cagggctggt ggaagggcga gaccaacgga cggattggct ggtttccttc
1081 aacgtacgta gaagaggagg gcatccagtg acggcaggaa cgtggacaag actcgcagat
1141 tttcttggga gagtcactcc agccctgaag tctgtctcta gctcctctgt gactcagagg
1201 ggaaatacca acctcccagt cttccactgc ccacagggat agggagggtg ttgagaatcc
1261 taaactcgaa ccgtttcact gtcagcctgc cctcggcgac ccatcactgg gtatgctatt
1321 gtacatagag gaaacctggg ctagccccac ccagagcgca gaggaggggg caccgacagc
1381 gctgcgagcc aggctctggg tagtggctga ggccagaggc ccatcgcctg cccctgtcca
1441 actgagatgg ccttcaggag cctaggtttg aacagcagat gctgtcccag gaagggctag
1501 ggacatcgga ggggacctgc ccccgcaccc tctgctcagc ccctggactc agccttgcct
1561 gtcttttcct gctgctccca gggggaggtg tcagacctcg ggaggcagac gggaccagag
1621 ccaggctgtt cactgtgggc ccacttgccc cactgtgcta gggcgcggga ggagagagca
1681 ctgtggtcgc cctctgcagc cactctggct cccaagactt ccctgactcc cccactcccc
1741 tccttgccag gggcacaccc ggaccccaca cggcaggccc ctctcttggg aggggccttt
1801 ggaatgatga aattccaacc ctgctgcccg gtcagcggta ccgtttcctg ccctctctct
1861 gagaggccct ttctggagtc ctgggaaggt gtctgcctgg ccgcgctgcc agatcagtac
1921 atcttttgta aaaaccctga aatgggcagg gaagaaaaca gggatttccc ctctctagat
1981 ccctgccagg tccctctcca ggaggcccct ctgctctcct gaagggtggt ccctgagggt
2041 ctgcccagcc ttggcacgag aggttggttc cagcccctgg cagggcttcc ttccaagggc
2101 ccctgcagcc tacaaactgg gcctcgggcg actcaaaata agtgctcttg ggggtggctc
2161 taccccatta cctcccccag ccacaactcc tggccttcga cttctggctg ggttagccag
2221 accctggttt ctctaccctg atgttgcatg agacctggta acagtgtctc cctcccagct
2281 ccttgccaaa gcctctgttg agacctgggc ttcttgtagc cccttctccc tctggccagc
2341 tgcacagcct gtgggaggtg cccggcccag gctgggtgtg ggggaagctg gtccctgctg
2401 tgggtggcgc tggggaccta ggggctcctt ctgaggttgg ccttgtggcc tctgggctgt
2461 atgcctctgg ggtgtaggga agaggcggga ggagtcatgg ggatggggag cggcaggggg
2521 agagaggggc cctcgacaaa ggcttgggaa atgaggggag gtggaggcag ggcaggggaa
2581 gcgaagagtc agccttggag agagcaccct ggggcctccg tgtcggggta cacccagcac
2641 tttgcgacct gcggcccagc aggcgcggag gatggcgggg aggaagccag cagcccctgt
2701 gtttactgtc gtcagaaagg tcttgtgttt tggttttggg gtttttgttt tgtttgtgtt
2761 ttgtttggct tgtttgtttt ttaaggggaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2821 aaaaaaaaaa aaaaaaaaa
//