LOCUS BC033015 4405 bp mRNA linear HUM 11-AUG-2006
DEFINITION Homo sapiens RAS p21 protein activator (GTPase activating protein)
1, mRNA (cDNA clone MGC:26760 IMAGE:4829173), complete cds.
ACCESSION BC033015
VERSION BC033015.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4405)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4405)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (21-JUN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 25, 2003 this sequence version replaced BC033015.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 34 Row: f Column: 8
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4506430.
FEATURES Location/Qualifiers
source 1..4405
/db_xref="H-InvDB:HIT000041761"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:26760 IMAGE:4829173"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..4405
/gene="RASA1"
/gene_synonym="CM-AVM"
/gene_synonym="CMAVM"
/gene_synonym="GAP"
/gene_synonym="p120GAP"
/gene_synonym="PKWS"
/gene_synonym="RASGAP"
/db_xref="GeneID:5921"
/db_xref="HGNC:HGNC:9871"
/db_xref="MIM:139150"
CDS 188..3331
/gene="RASA1"
/gene_synonym="CM-AVM"
/gene_synonym="CMAVM"
/gene_synonym="GAP"
/gene_synonym="p120GAP"
/gene_synonym="PKWS"
/gene_synonym="RASGAP"
/codon_start=1
/product="RAS p21 protein activator (GTPase activating
protein) 1"
/protein_id="AAH33015.1"
/db_xref="GeneID:5921"
/db_xref="HGNC:HGNC:9871"
/db_xref="MIM:139150"
/translation="MMAAEAGSEEGGPVTAGAGGGGAAAGSSAYPAVCRVKIPAALPV
AAAPYPGLVETGVAGTLGGGAALGSEFLGAGSVAGALGGAGLTGGGTAAGVAGAAAGV
AGAAVAGPSGDMALTKLPTSLLAETLGPGGGFPPLPPPPYLPPLGAGLGTVDEGDSLD
GPEYEEEEVAIPLTAPPTNQWYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVL
SFLSQMNVVNHFRIIAMCGDYYIGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVAPPE
PVEDRRRVRAILPYTKVPDTDEISFLKGDMFIVHNELEDGWMWVTNLRTDEQGLIVED
LVEEVGREEDPHEGKIWFHGKISKQEAYNLLMTVGQVCSFLVRPSDNTPGDYSLYFRT
NENIQRFKICPTPNNQFMMGGRYYNSIGDIIDHYRKEQIVEGYYLKEPVPMQDQEQVL
NDTVDGKEIYNTIRRKTKDAFYKNIVKKGYLLKKGKGKRWKNLYFILEGSDAQLIYFE
SEKRATKPKGLIDLSVCSVYVVHDSLFGRPNCFQIVVQHFSEEHYIFYFAGETPEQAE
DWMKGLQAFCNLRKSSPGTSNKRLRQVSSLVLHIEEAHKLPVKHFTNPYCNIYLNSVQ
VAKTHAREGQNPVWSEEFVFDDLPPDINRFEITLSNKTKKSKDPDILFMRCQLSRLQK
GHATDEWFLLSSHIPLKGIEPGSLRVRARYSMEKIMPEEEYSEFKELILQKELHVVYA
LSHVCGQDRTLLASILLRIFLHEKLESLLLCTLNDREISMEDEATTLFRATTLASTLM
EQYMKATATQFVHHALKDSILKIMESKQSCELSPSKLEKNEDVNTNLTHLLNILSELV
EKIFMASEILPPTLRYIYGCLQKSVQHKWPTNTTMRTRVVSGFVFLRLICPAILNPRM
FNIISDSPSPIAARTLILVAKSVQNLANLVEFGAKEPYMEGVNPFIKSNKHRMIMFLD
ELGNVPELPDTTEHSRTDLSRDLAALHEICVAHSDELRTLSNERGAQQHVLKKLLAIT
ELLQQKQNQYTKTNDVR"
BASE COUNT 1312 a 873 c 987 g 1233 t
ORIGIN
1 agctggggag cctgggctgt ggccctagga gggggcgcgg cggcgggctc tctccttttg
61 ttgttgtttc ctcagcctgg ggagctgaag gggagacgcg tctgggtggg gctgctcgga
121 gcccgggcct ggtggcccct ggggctcccg ggcgggcagg gtagggcaga gtagagcggg
181 cttcaacatg atggcggccg aggccggcag tgaggagggc ggcccggtaa cagccggagc
241 tggaggaggc ggcgcggcag cgggctccag tgcctatccc gcagtgtgtc gggtgaagat
301 acccgcggcc ctgcctgtgg cagccgcccc ctatcctggg ctggtggaga ccggagtggc
361 tggaactctg ggtggcggag ccgctttggg gtcagagttc ctaggagccg ggtctgtggc
421 aggggcactg gggggagctg gactgacagg gggaggtact gctgctggcg tagctggtgc
481 tgctgctggc gtggccggtg ctgctgttgc tggacctagt ggagacatgg ctctcaccaa
541 actgcccact tcgttgcttg ctgagactct cgggccaggc ggcggttttc cccctctgcc
601 ccctccccct tacctgcccc ctttgggggc gggcctcggg acagtggacg aaggtgactc
661 tctggatgga ccagaatacg aggaggaaga ggtggccata ccgttgaccg ctcctccaac
721 taaccagtgg tatcacggaa aacttgacag aacgatagca gaagaacgcc tcaggcaggc
781 agggaagtct ggcagttatc ttataagaga gagtgatcgg aggccagggt cctttgtact
841 ttcatttctt agccagatga atgttgtcaa ccattttagg attattgcta tgtgtggaga
901 ttactacatt ggtggaagac gtttttcttc actgtcagac ctaataggtt attacagtca
961 tgtttcttgt ttgcttaaag gagaaaaatt actttaccca gttgcaccac cagagccagt
1021 agaagataga aggcgtgtac gagctattct accttacaca aaagtaccag acactgatga
1081 aataagtttc ttaaaaggag atatgttcat tgttcataat gaattagaag atggatggat
1141 gtgggttaca aatttaagaa cagatgaaca aggccttatt gttgaagacc tagtagaaga
1201 ggtgggccgg gaagaagatc cacatgaagg aaaaatatgg ttccatggga agatttccaa
1261 acaggaagct tataatttac taatgacagt tggtcaagtc tgcagttttc ttgtgaggcc
1321 ctcagataat actcctggcg attattcact ttatttccgg accaatgaaa atattcagcg
1381 atttaaaata tgtccaacgc caaacaatca gtttatgatg ggaggccggt attataacag
1441 cattggggac atcatagatc actatcgaaa agaacagatt gttgaaggat attatcttaa
1501 ggaacctgta ccaatgcagg atcaagaaca agtactcaat gacacagtgg atggcaagga
1561 aatctataat accatccgtc gtaaaacaaa ggatgccttt tataaaaaca ttgttaagaa
1621 aggttatctt ctgaaaaagg gcaaaggaaa acgttggaaa aatttatatt ttatcttaga
1681 gggtagtgat gcccaactta tttattttga aagcgaaaaa cgagctacca aaccaaaagg
1741 attaatagat ctcagtgtat gttctgtcta tgtcgttcat gatagtctct ttggcaggcc
1801 aaactgtttt cagatagtag ttcagcactt tagtgaagaa cattacatct tttactttgc
1861 aggagaaact ccagaacaag cagaggattg gatgaaaggt ctgcaggcat tttgcaattt
1921 acggaaaagt agtccaggga catccaataa acgccttcgt caggtcagca gccttgtttt
1981 acatattgaa gaagcccata aactcccagt aaaacatttt actaatccat attgtaacat
2041 ctacctgaat agtgtccaag tagcaaaaac tcatgcaagg gaagggcaaa acccagtatg
2101 gtcagaagag tttgtctttg atgatcttcc tcctgacatc aatagatttg aaataactct
2161 tagtaataaa acaaagaaaa gcaaagatcc tgatatctta tttatgcgct gccagttgag
2221 ccgattacag aaagggcatg ccacagatga atggtttctg ctcagctccc atataccatt
2281 aaaaggtatt gaaccagggt ccctgcgtgt tcgagcacga tactctatgg aaaaaatcat
2341 gccagaagaa gagtacagtg aatttaaaga gcttatactg caaaaggaac ttcatgtagt
2401 ctatgcttta tcacatgtat gtggacaaga ccgaacacta ctggccagca tcctactgag
2461 gatttttctt cacgaaaagc ttgaatcgtt gttgttatgc acactaaatg acagagaaat
2521 aagcatggaa gatgaagcca ctaccctatt tcgagccaca acacttgcaa gcaccttgat
2581 ggagcagtat atgaaagcca ctgctacaca gtttgttcat catgctttga aagactctat
2641 tttaaagata atggaaagca agcagtcttg tgagttaagt ccatcaaagt tagaaaaaaa
2701 tgaagatgtg aacactaatt taacacacct attgaacata ctttcagagc ttgtggagaa
2761 aatattcatg gcttcagaaa tacttccacc gacattgaga tatatttatg ggtgtttaca
2821 gaaatctgtt cagcataagt ggcctacaaa taccaccatg agaacaagag ttgttagtgg
2881 ttttgttttt cttcgactca tctgtcctgc catcctgaat ccacggatgt tcaatatcat
2941 ctcagattct ccatctccta ttgctgcaag aacactgata ttagtggcta aatctgtgca
3001 gaacttagca aatcttgtgg aatttggagc taaggagccc tacatggaag gtgtcaatcc
3061 attcatcaaa agcaacaaac atcgtatgat catgttttta gatgaacttg ggaatgtacc
3121 tgaacttccg gacactacag agcattctag aacggacctg tcccgtgatt tagcagcatt
3181 gcatgagatt tgcgtggctc attcagatga acttcgaacg ctcagtaatg agcgtggtgc
3241 acagcagcac gtattgaaaa agcttctggc tataacagaa ctgcttcaac aaaaacaaaa
3301 ccagtataca aaaaccaatg atgtcaggta gcagccttcg ccccagtgtt ctgcatggat
3361 tcagcatgtc caacatggta attcacttca gtttaatgtc tcctttgctc ttgccaaaaa
3421 atagcacact tttccacatt ccagtgatgt gtgagctatg caaacaaaat ccaagattct
3481 gctggtgaat aactatgcca gcaaccttgt aagctatctg tgcaggatat ttgcactatt
3541 tccacatgga atcaatcttt aacaacctct gagccttggt gtacagacca cctttcacaa
3601 aacgaaatgc tatgactgta tcttgatatc tcgaactttc aaaatatatt ttcagtacac
3661 ccagttgcca aagttttgct gtctcttaga gaaagaacta tgaaatcaac tgacaagaaa
3721 cacattctta ttgacaattg tgtataactg gattgcagac tgttcttact gtaactactt
3781 cctgattagg aatatgacca tttgactgtt caatgattat ttgtatttac agtttccaga
3841 gtttgtcatt ataataggaa caatctttgc tgtatacttt taaaaaatac tctgctattt
3901 ctcttgctgg aactgttgaa agaaaatata tagaatgatc tattgctcat cagctttatt
3961 ttttaaacat acgacttatt ttgttgaaat tgtcaaagac tgtatttaga tctcataatg
4021 ctttgttaaa tgtttacaag taaatagttt gaattcagta aatattattg gttgttgtat
4081 tgatcaatgc atgttaccca ttcaaccatt ttatagacta ccaatttctt ttatgttaac
4141 tagaatgctt ttgttaaaag ttatttgttc attatttgtg ctaccccttt gattatgcag
4201 acaacctcat cagctgccta acttatccat ctttgaactt ctgactactt gttgtatctg
4261 ctggatattt agttcaactg tatagtttta tttacttctg tatgtgtatt tttgtgaagt
4321 attcacaaag gttaagttaa aataaaacca agggatatct tgcaaaaaaa aaaaaaaaaa
4381 aaaaaaaaca aaaaaaaaaa aaaaa
//