LOCUS BC032835 3316 bp mRNA linear HUM 19-MAR-2009
DEFINITION Homo sapiens transmembrane protein 67, mRNA (cDNA clone MGC:26979
IMAGE:4825770), complete cds.
ACCESSION BC032835
VERSION BC032835.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3316)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3316)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (07-JUN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Sep 16, 2003 this sequence version replaced BC032835.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 33 Row: l Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 42476194
The stop codon of the CDS annotated on this record is located > 55
bases upstream of a splice junction, and therefore the mRNA is
predicted to be subject to nonsense-mediated mRNA decay (NMD).
FEATURES Location/Qualifiers
source 1..3316
/db_xref="H-InvDB:HIT000051069"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:26979 IMAGE:4825770"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3316
/gene="TMEM67"
/gene_synonym="JBTS6"
/gene_synonym="MECKELIN"
/gene_synonym="TNEM67"
/db_xref="GeneID:91147"
/db_xref="HGNC:HGNC:28396"
/db_xref="MIM:609884"
CDS 20..2977
/gene="TMEM67"
/gene_synonym="JBTS6"
/gene_synonym="MECKELIN"
/gene_synonym="TNEM67"
/codon_start=1
/product="TMEM67 protein"
/protein_id="AAH32835.1"
/db_xref="GeneID:91147"
/db_xref="HGNC:HGNC:28396"
/db_xref="MIM:609884"
/translation="MAVWSLLSARAVTAFLLLFLPRFLQAQTFSFPFQQPEKCDNNQY
FDISALSCVPCGANQRQDARGTSCVCLPGFQMISNNGGPAIICKKCPENMKGVTEDGW
NCISCPSDLTAEGKCHCPIGHILVERDINGTLLSQATCELCDGNENSFMVVNALGDRC
VRCEPTFVNTSRSCACSEPNILTGGLCFSSTGNFPLRRISAARYGEVGMSLTSEWFAK
YLQSSAAACWVYANLTSCQALGNMCVMNMNSYDFATFDACGLFQFIFENTAGLSTVHS
ISFWRQNLPWLFYGDQLGLAPQVLSSTSLPTNFSFKGENQNTKLKFVAASYDIRGNFL
KWQTLEGGVLQLCPDTETRLNAAYSFGTTYQQNCEIPISKILIDFPTPIFYDVYLEYT
DENQHQYILAVPVLNLNLQHNKIFVNQDSNSGKWLLTRRIFLVDAVSGRENDLGTQPR
VIRVATQISLSVHLVPNTINGNIYPPLITIAYSDIDIKDANSQSVKVSFSVTYEMDHG
EAHVQTDIALGVLGGLAVLASLLKTAGWKRRIGSPMIDLQTVVKFLVYYAGDLANVFF
IITVGTGLYWLIFFKAQKSVSVLLPMPIQEERFVTYVGCAFALKALQFLHKLISQITI
DVFFIDWERPKGKVLKAVEGEGGVRSATVPVSIWRTYFVANEWNEIQTVRKINSLFQV
LTVLFFLEVVGFKNLALMDSSSSLSRNPPSYIAPYSCILRYAVSAALWLAIGIIQVVF
FAVFYERFIEDKIRQFVDLCSMSNISVFLLSHKCFGYYIHGRSVHGHADTNMEEMNMN
LKREAENLCSQRGLVPNTDGQTFEIAISNQMRQHYDRIHETLIRKNGPARLLSSSAST
FEQSIKAYHMMNKFLGSFIDHVHKEMDYFIKDKLLLERILGMEFMEPMEKSIFYNDEG
YSFSSVLYYGNEATLLIFDLLFFCVVDLACQNFILASFLTYLQQEIFRYIRNTVGQKN
LASKTLVDQRFLI"
BASE COUNT 984 a 607 c 679 g 1046 t
ORIGIN
1 gggtggggct ggggtggcaa tggcggtttg gtccctctta tccgcccggg ccgtgaccgc
61 gttccttctg ttgttcctcc ctcgcttctt acaggcccag accttctctt tccctttcca
121 gcagccggag aagtgcgaca acaaccagta ctttgatatc tccgccctct cgtgtgttcc
181 ttgtggagct aaccagaggc aagatgcccg aggaacttca tgtgtatgtc taccaggatt
241 tcagatgatc tctaataatg gaggacctgc tattatttgt aaaaagtgcc cagaaaacat
301 gaaaggtgtt acagaagatg gctggaactg catttcttgc cctagtgact taactgccga
361 aggaaaatgt cactgtccca ttggccatat tttagtggaa agagacatta atggaacatt
421 gttgtctcaa gcaacttgtg agctctgtga tggaaatgaa aactctttta tggtagtaaa
481 tgctttagga gacaggtgcg tccgatgtga gccaacattt gttaatacca gcaggtcctg
541 tgcatgttca gaacctaaca ttttaacagg gggattatgt ttcagcagca cagggaattt
601 tcctctacgt agaatttcag ctgcacgtta tggagaagtt ggcatgtctt taacttcaga
661 atggtttgca aagtatttgc aatcatcagc agctgcatgt tgggtatatg ccaatctaac
721 atcttgtcaa gctcttggaa atatgtgtgt gatgaacatg aattcttacg actttgccac
781 atttgatgca tgtggactat ttcagtttat ctttgaaaat actgctggac tgagcactgt
841 tcattctatt tcattttgga gacagaatct tccttggctg ttttatggag accagttagg
901 attagcacct caagtgctca gttctacctc tcttcctaca aatttcagtt ttaaaggaga
961 aaaccagaat acaaaactga agtttgttgc tgcttcctat gatataagag gaaattttct
1021 caagtggcaa actttagaag gaggtgtttt acagctttgt ccagacacag agacaaggct
1081 aaatgctgct tattcatttg gaacaaccta ccaacaaaat tgtgagattc ctatctctaa
1141 gatcttaatt gactttccca ctcctatatt ttatgatgtg taccttgaat atactgatga
1201 aaatcaacat caatatattt tggctgtgcc tgtgttaaac ctaaatcttc aacataataa
1261 gatatttgtg aaccaagaca gcaactctgg aaagtggctt ctaactcggc gcattttctt
1321 agtggatgca gtaagtggac gagaaaatga cttaggaact cagccaagag taattcgagt
1381 tgctactcaa atatcactga gtgtccacct tgtacccaac acaataaatg gaaacatcta
1441 ccctccctta atcaccattg cctacagtga cattgatatc aaagatgcca acagccagtc
1501 tgtgaaggtt tctttctcag tcacatatga aatggatcat ggagaagcac atgtccagac
1561 agatattgct ttgggtgtat tgggtgggct agctgtttta gcatctcttt tgaagacagc
1621 aggatggaag aggcgcattg ggagtcccat gattgattta cagacagttg tgaaattctt
1681 ggtgtactat gctggtgatc tggccaatgt tttctttatc atcacagtgg gaacaggtct
1741 ttactggctt attttcttca aagcacagaa gtctgtgtct gttttgctgc caatgccaat
1801 tcaggaagaa cgttttgtca cttatgttgg atgtgccttt gctctgaagg cactacaatt
1861 tttgcataag ctcatatccc agattacaat agatgtattc tttattgatt gggagcgacc
1921 taaaggaaag gttcttaaag ctgttgaagg tgagggtggt gtacgaagtg ccactgttcc
1981 tgtaagcata tggagaacat attttgtagc aaatgaatgg aatgaaattc agactgtgag
2041 aaaaattaat tcactctttc aagtacttac tgtcctcttc tttttggagg ttgtgggatt
2101 caagaactta gcattaatgg actcatcttc tagtctttct agaaacccac ctagctacat
2161 agctccttat agctgcattt tgagatatgc agtgtctgct gctctttggc tagccattgg
2221 aattatacag gtcgtgttct ttgctgtctt ttatgagaga tttatagaag ataaaattcg
2281 acagttcgtt gatttatgct ctatgagtaa tatatcagtg tttctgttat cccacaaatg
2341 ttttggatat tacattcatg gtagatcagt acatgggcat gcagatacta atatggaaga
2401 aatgaatatg aaccttaaaa gagaagcgga aaatttgtgt agccagagag gtttggtacc
2461 caacacagat ggtcagactt ttgagattgc aatttctaac cagatgagac aacattatga
2521 cagaattcat gagacactaa taaggaaaaa tggtcctgct agactactga gttcatcagc
2581 aagtactttt gagcagagta taaaagcata tcatatgatg aataaatttc ttggctcctt
2641 cattgaccat gttcataagg aaatggatta ctttataaaa gataagttgc ttcttgaaag
2701 aattcttgga atggaattca tggaaccaat ggaaaaaagc atcttttaca atgatgaagg
2761 ttattctttc agcagtgtcc tgtattatgg aaatgaagct actcttctta tttttgatct
2821 gctgttcttc tgtgttgtgg atttggcttg ccaaaatttt attttagcat ccttccttac
2881 atatctacaa caagagattt ttagatatat ccgtaataca gtaggacaaa agaatttggc
2941 atccaaaaca ttggtggatc aaagattttt gatttaactt cctgaataaa taacttaaag
3001 actcagtata atcatggcca aaaaaaagtc atgatatcag agacaagggt tcaccatgtt
3061 gcccaggcta gtcttgaact cctgatcgag agattcaccc acctcggcct ccaaaagtgc
3121 tgggattaca ggtgtcagcc actacacatg gccaggatta gtttcttaga atgtgctttt
3181 aacattgagt aaactatgaa tgctggaatt tttattttta gtttaaaata tctgccccaa
3241 aatatatttt tttcttgcta ataaattaat aatatgatat taaaaaaaaa aaaaaaaaac
3301 caaaaaaaaa aaaaaa
//