LOCUS BC032722 1748 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens tumor necrosis factor (ligand) superfamily, member 10,
mRNA (cDNA clone MGC:45300 IMAGE:5504670), complete cds.
ACCESSION BC032722
VERSION BC032722.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1748)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1748)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (06-JUN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Lou Staudt
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 69 Row: h Column: 20
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 23510439.
FEATURES Location/Qualifiers
source 1..1748
/db_xref="H-InvDB:HIT000041693"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:45300 IMAGE:5504670"
/tissue_type="Lymph, lymphoma"
/clone_lib="NIH_MGC_85"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1748
/gene="TNFSF10"
/gene_synonym="Apo-2L"
/gene_synonym="APO2L"
/gene_synonym="CD253"
/gene_synonym="TL2"
/gene_synonym="TRAIL"
/db_xref="GeneID:8743"
/db_xref="HGNC:HGNC:11925"
/db_xref="MIM:603598"
CDS 76..921
/gene="TNFSF10"
/gene_synonym="Apo-2L"
/gene_synonym="APO2L"
/gene_synonym="CD253"
/gene_synonym="TL2"
/gene_synonym="TRAIL"
/codon_start=1
/product="tumor necrosis factor (ligand) superfamily,
member 10"
/protein_id="AAH32722.1"
/db_xref="GeneID:8743"
/db_xref="HGNC:HGNC:11925"
/db_xref="MIM:603598"
/translation="MAMMEVQGGPSLGQTCVLIVIFTVLLQSLCVAVTYVYFTNELKQ
MQDKYSKSGIACFLKEDDSYWDPNDEESMNSPCWQVKWQLRQLVRKMILRTSEETIST
VQEKQQNISPLVRERGPQRVAAHITGTRGRSNTLSSPNSKNEKALGRKINSWESSRSG
HSFLSNLHLRNGELVIHEKGFYYIYSQTYFRFQEEIKENTKNDKQMVQYIYKYTSYPD
PILLMKSARNSCWSKDAEYGLYSIYQGGIFELKENDRIFVSVTNEHLIDMDHEASFFG
AFLVG"
BASE COUNT 597 a 361 c 374 g 416 t
ORIGIN
1 ccacgcgtcc gagaaggaag ggcttcagtg accggctgcc tggctgactt acagcagtca
61 gactctgaca ggatcatggc tatgatggag gtccaggggg gacccagcct gggacagacc
121 tgcgtgctga tcgtgatctt cacagtgctc ctgcagtctc tctgtgtggc tgtaacttac
181 gtgtacttta ccaacgagct gaagcagatg caggacaagt actccaaaag tggcattgct
241 tgtttcttaa aagaagatga cagttattgg gaccccaatg acgaagagag tatgaacagc
301 ccctgctggc aagtcaagtg gcaactccgt cagctcgtta gaaagatgat tttgagaacc
361 tctgaggaaa ccatttctac agttcaagaa aagcaacaaa atatttctcc cctagtgaga
421 gaaagaggtc ctcagagagt agcagctcac ataactggga ccagaggaag aagcaacaca
481 ttgtcttctc caaactccaa gaatgaaaag gctctgggcc gcaaaataaa ctcctgggaa
541 tcatcaagga gtgggcattc attcctgagc aacttgcact tgaggaatgg tgaactggtc
601 atccatgaaa aagggtttta ctacatctat tcccaaacat actttcgatt tcaggaggaa
661 ataaaagaaa acacaaagaa cgacaaacaa atggtccaat atatttacaa atacacaagt
721 tatcctgacc ctatattgtt gatgaaaagt gctagaaata gttgttggtc taaagatgca
781 gaatatggac tctattccat ctatcaaggg ggaatatttg agcttaagga aaatgacaga
841 atttttgttt ctgtaacaaa tgagcacttg atagacatgg accatgaagc cagttttttc
901 ggggcctttt tagttggcta actgacctgg aaagaaaaag caataacctc aaagtgacta
961 ttcagttttc aggatgatac actatgaaga tgtttcaaaa aatctgacca aaacaaacaa
1021 acagaaaaca gaaaacaaaa aaacctctat gcaatctgag tagagcagcc acaaccaaaa
1081 aattctacaa cacacactgt tctgaaagtg actcacttat cccaagaaaa tgaaattgct
1141 gaaagatctt tcaggactct acctcatatc agtttgctag cagaaatcta gaagactgtc
1201 agcttccaaa cattaatgca atggttaaca tcttctgtct ttataatcta ctccttgtaa
1261 agactgtaga agaaagcgca acaatccatc tctcaagtag tgtatcacag tagtagcctc
1321 caggtttcct taagggacaa catccttaag tcaaaagaga gaagaggcac cactaaaaga
1381 tcgcagtttg cctggtgcag tggctcacac ctgtaatccc aacattttgg gaacccaagg
1441 tgggtagatc acgagatcaa gagatcaaga ccatagtgac caacatagtg aaaccccatc
1501 tctactgaaa gtgcaaaaat tagctgggtg tgttggcaca tgcctgtagt cccagctact
1561 tgagaggctg aggcaggaga atcgtttgaa cccgggaggc agaggttgca gtgtggtgag
1621 atcatgccac tacactccag cctggcgaca gagcgagact tggtttcaaa aaaaaaaaaa
1681 aaaaaaactt cagtaagtac gtgttatttt tttcaataaa attctattac agtaaaaaaa
1741 aaaaaaaa
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