LOCUS BC032496 2000 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens FYN oncogene related to SRC, FGR, YES, mRNA (cDNA
clone MGC:45350 IMAGE:5219761), complete cds.
ACCESSION BC032496
VERSION BC032496.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2000)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2000)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (06-JUN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 69 Row: a Column: 1.
FEATURES Location/Qualifiers
source 1..2000
/db_xref="H-InvDB:HIT000041568"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:45350 IMAGE:5219761"
/tissue_type="Blood, adult leukocytes"
/clone_lib="NIH_MGC_118"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2000
/gene="FYN"
/gene_synonym="MGC45350"
/gene_synonym="SLK"
/gene_synonym="SYN"
/db_xref="GeneID:2534"
/db_xref="HGNC:HGNC:4037"
/db_xref="MIM:137025"
CDS 55..1503
/gene="FYN"
/gene_synonym="MGC45350"
/gene_synonym="SLK"
/gene_synonym="SYN"
/codon_start=1
/product="FYN oncogene related to SRC, FGR, YES"
/protein_id="AAH32496.1"
/db_xref="GeneID:2534"
/db_xref="HGNC:HGNC:4037"
/db_xref="MIM:137025"
/translation="MGCVQCKDKEATKLTEERDGSLNQSSGYRYGTDPTPQHYPSFGV
TSIPNYNNFHAAGGQGLTVFGGVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLS
FHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAE
RQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTR
AQFETLQQLVQHYSGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYA
VVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR
DLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS
DVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKK
DPEERPTFEYLQSFLEDYFTATEPQYQPGENL"
BASE COUNT 612 a 474 c 467 g 447 t
ORIGIN
1 cagcgcaggt ctgaggagct gagaagggag gcttacgtga agggaattta gataatgggc
61 tgtgtgcaat gtaaggataa agaagcaaca aaactgacgg aggagaggga cggcagcctg
121 aaccagagct ctgggtaccg ctatggcaca gaccccaccc ctcagcacta ccccagcttc
181 ggtgtgacct ccatccccaa ctacaacaac ttccacgcag ccgggggcca aggactcacc
241 gtctttggag gtgtgaactc ttcgtctcat acggggacct tgcgtacgag aggaggaaca
301 ggagtgacac tctttgtggc cctttatgac tatgaagcac ggacagaaga tgacctgagt
361 tttcacaaag gagaaaaatt tcaaatattg aacagctcgg aaggagattg gtgggaagcc
421 cgctccttga caactggaga gacaggttac attcccagca attatgtggc tccagttgac
481 tctatccagg cagaagagtg gtactttgga aaacttggcc gaaaagatgc tgagcgacag
541 ctattgtcct ttggaaaccc aagaggtacc tttcttatcc gcgagagtga aaccaccaaa
601 ggtgcctatt cactttctat ccgtgattgg gatgatatga aaggagacca tgtcaaacat
661 tataaaattc gcaaacttga caatggtgga tactacatta ccacccgggc ccagtttgaa
721 acacttcagc agcttgtaca acattactca ggtacctgga atggaaacac aaaagtagcc
781 ataaagactc ttaaaccagg cacaatgtcc cccgaatcat tccttgagga agcgcagatc
841 atgaagaagc tgaagcacga caagctggtc cagctctatg cagtggtgtc tgaggagccc
901 atctacatcg tcaccgagta tatgaacaaa ggaagtttac tggatttctt aaaagatgga
961 gaaggaagag ctctgaaatt accaaatctt gtggacatgg cagcacaggt ggctgcagga
1021 atggcttaca tcgagcgcat gaattatatc catagagatc tgcgatcagc aaacattcta
1081 gtggggaatg gactcatatg caagattgct gacttcggat tggcccgatt gatagaagac
1141 aatgagtaca cagcaagaca aggtgcaaag ttccccatca agtggacggc ccccgaggca
1201 gccctgtacg ggaggttcac aatcaagtct gacgtgtggt cttttggaat cttactcaca
1261 gagctggtca ccaaaggaag agtgccatac ccaggcatga acaaccggga ggtgctggag
1321 caggtggagc gaggctacag gatgccctgc ccgcaggact gccccatctc tctgcatgag
1381 ctcatgatcc actgctggaa aaaggaccct gaagaacgcc ccacttttga gtacttgcag
1441 agcttcctgg aagactactt taccgcgaca gagccccagt accaacctgg tgaaaacctg
1501 taaggcccgg gtctgcggag agaggccttg tcccagaggc tgccccaccc ctccccatta
1561 gctttcaatt ccgtagccag ctgctcccca gcagcggaac cgcccaggat cagattgcat
1621 gtgactctga agctgacgaa cttccatggc cctcattaat gacacttgtc cccaaatccg
1681 aacctcctct gtgaagcatt cgagacagaa ccttgttatt tctcagactt tggaaaatgc
1741 attgtatcga tgttatgtaa aaggccaaac ctctgttcag tgtaaatagt tactccagtg
1801 ccaacaatcc tagtgctttc cttttttaaa aatgcaaatc ctatgtgatt ttaactctgt
1861 cttcacctga ttcaactaaa aaaaaaaaag tattattttc caaaagtggc ctctttgtct
1921 aaaacaataa aatttttttt catgttttaa caaaaaccaa aaaaaaaaaa aaaaaaaaaa
1981 aaaaaaaaaa aaaaaaaaaa
//