LOCUS BC031835 2328 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens neurotrophic tyrosine kinase, receptor, type 2, mRNA
(cDNA clone MGC:24881 IMAGE:4941763), complete cds.
ACCESSION BC031835
VERSION BC031835.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2328)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2328)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (06-JUN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: David N. Louis, M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 29 Row: p Column: 16
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 65506645.
FEATURES Location/Qualifiers
source 1..2328
/db_xref="H-InvDB:HIT000041379"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:24881 IMAGE:4941763"
/tissue_type="Brain, anaplastic oligodendroglioma with
1p/19q loss"
/clone_lib="NCI_CGAP_Brn67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2328
/gene="NTRK2"
/gene_synonym="GP145-TrkB"
/gene_synonym="TRKB"
/db_xref="GeneID:4915"
/db_xref="HGNC:HGNC:8032"
/db_xref="MIM:600456"
CDS 410..1843
/gene="NTRK2"
/gene_synonym="GP145-TrkB"
/gene_synonym="TRKB"
/codon_start=1
/product="neurotrophic tyrosine kinase, receptor, type 2"
/protein_id="AAH31835.1"
/db_xref="GeneID:4915"
/db_xref="HGNC:HGNC:8032"
/db_xref="MIM:600456"
/translation="MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIW
CSDPSPGIVAFPRLEPNSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSG
LKFVAHKAFLKNSNLQHINFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIK
TLQEAKSSPDTQDLYCLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSC
SVAGDPVPNMYWDVGNLVSKHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQ
DSVNLTVHFAPTITFLESPTSDHHWCIPFTVKGNPKPALQWFYNGAILNESKYICTKI
HVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHFMGWPGIDDGANPNY
PDVIYEDYGTAANDIGDTTNRSNEIPSTDVTDKTGREHLSVYAVVVIASVVGFCLLVM
LFLLKLARHSKFGMKGFVLFHKIPLDG"
BASE COUNT 636 a 545 c 591 g 556 t
ORIGIN
1 agctggccgc cggcgggcgt gaggcgccgg agcccggcct cgaggtgcat accggacccc
61 cattcgcatc taacaaggaa tctgcgcccc agagagtccc gggagcgccg ccggtcggtg
121 cccggcgcgc cgggccatgc agcgacggcc gccgcggagc tccgagcagc ggtagcgccc
181 ccctgtaaag cggttcgcta tgccggggcc actgtgaacc ctgccgcctg ccggaacact
241 cttcgctccg gaccagctca gcctctgata agctggactc ggcacgcccg caacaagcac
301 cgaggagtta agagagccgc aagcgcaggg aaggcctccc ggcacgggtg ggggaaagcg
361 gccggtgcag cgcggggaca ggcactcggg ctggcactgg ctgctaggga tgtcgtcctg
421 gataaggtgg catggacccg ccatggcgcg gctctggggc ttctgctggc tggttgtggg
481 cttctggagg gccgctttcg cctgtcccac gtcctgcaaa tgcagtgcct ctcggatctg
541 gtgcagcgac ccttctcctg gcatcgtggc atttccgaga ttggagccta acagtgtaga
601 tcctgagaac atcaccgaaa ttttcatcgc aaaccagaaa aggttagaaa tcatcaacga
661 agatgatgtt gaagcttatg tgggactgag aaatctgaca attgtggatt ctggattaaa
721 atttgtggct cataaagcat ttctgaaaaa cagcaacctg cagcacatca attttacccg
781 aaacaaactg acgagtttgt ctaggaaaca tttccgtcac cttgacttgt ctgaactgat
841 cctggtgggc aatccattta catgctcctg tgacattatg tggatcaaga ctctccaaga
901 ggctaaatcc agtccagaca ctcaggattt gtactgcctg aatgaaagca gcaagaatat
961 tcccctggca aacctgcaga tacccaattg tggtttgcca tctgcaaatc tggccgcacc
1021 taacctcact gtggaggaag gaaagtctat cacattatcc tgtagtgtgg caggtgatcc
1081 ggttcctaat atgtattggg atgttggtaa cctggtttcc aaacatatga atgaaacaag
1141 ccacacacag ggctccttaa ggataactaa catttcatcc gatgacagtg ggaagcagat
1201 ctcttgtgtg gcggaaaatc ttgtaggaga agatcaagat tctgtcaacc tcactgtgca
1261 ttttgcacca actatcacat ttctcgaatc tccaacctca gaccaccact ggtgcattcc
1321 attcactgtg aaaggcaacc ccaaaccagc gcttcagtgg ttctataacg gggcaatatt
1381 gaatgagtcc aaatacatct gtactaaaat acatgttacc aatcacacgg agtaccacgg
1441 ctgcctccag ctggataatc ccactcacat gaacaatggg gactacactc taatagccaa
1501 gaatgagtat gggaaggatg agaaacagat ttctgctcac ttcatgggct ggcctggaat
1561 tgacgatggt gcaaacccaa attatcctga tgtaatttat gaagattatg gaactgcagc
1621 gaatgacatc ggggacacca cgaacagaag taatgaaatc ccttccacag acgtcactga
1681 taaaaccggt cgggaacatc tctcggtcta tgctgtggtg gtgattgcgt ctgtggtggg
1741 attttgcctt ttggtaatgc tgtttctgct taagttggca agacactcca agtttggcat
1801 gaaaggtttt gttttgtttc ataagatccc actggatggg tagctgaaat aaaggaaaag
1861 acagagaaag gggctgtggt gcttgttggt tgatgctgcc atgtaagctg gactcctggg
1921 actgctgttg gcttatcccg ggaagtgctg cttatctggg gttttctggt agatgtgggc
1981 ggtgtttgga ggctgtacta tatgaagcct gcatatactg tgagctgtga ttggggaaca
2041 ccaatgcaga ggtaactctc aggcagctaa gcagcacctc aagaaaacat gttaaattaa
2101 tgcttctctt cttacagtag ttcaaataca aaactgaaat gaaatcccat tggattgtac
2161 ttctcttctg aaaagtgtgc tttttgaccc tactggacat ttattgactt aattgcttct
2221 gtttattaaa attgacctgc aaagttaaaa aaaaattaaa gttgagaaca ggtataagtg
2281 caaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa
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