LOCUS BC031086 2128 bp mRNA linear HUM 28-JUL-2005
DEFINITION Homo sapiens leptin receptor, mRNA (cDNA clone IMAGE:5284598),
partial cds.
ACCESSION BC031086
VERSION BC031086.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2128)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2128)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-JUN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 48 Row: i Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 40254463.
FEATURES Location/Qualifiers
source 1..2128
/db_xref="H-InvDB:HIT000092292"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:5284598"
/tissue_type="Brain, hippocampus"
/clone_lib="NIH_MGC_95"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..>2128
/gene="LEPR"
/gene_synonym="OBR"
/db_xref="GeneID:3953"
/db_xref="MIM:601007"
CDS 151..>2128
/gene="LEPR"
/gene_synonym="OBR"
/codon_start=1
/product="LEPR protein"
/protein_id="AAH31086.1"
/db_xref="GeneID:3953"
/db_xref="MIM:601007"
/translation="MICQKFCVVLLHWEFIYVITAFNLSYPITPWRFKLSCMPPNSTY
DYFLLPAGLSKNTSNSNGHYETAVEPKFNSSGTHFSNLSKTTFHCCFRSEQDRNCSLC
ADNIEGKTFVSTVNSLVFQQIDANWNIQCWLKGDLKLFICYVESLFKNLFRNYNYKVH
LLYVLPEVLEDSPLVPQKGSFQMVHCNCSVHECCECLVPVPTAKLNDTLLMCLKITSG
GVIFQSPLMSVQPINMVKPDPPLGLHMEITDDGNLKISWSSPPLVPFPLQYQVKYSEN
STTVIREADKIVSATSLLVDSILPGSSYEVQVRGKRLDGPGIWSDWSTPRVFTTQDVI
YFPPKILTSVGSNVSFHCIYKKENKIVPSKEIVWWMNLAEKIPQSQYDVVSDNVSKVT
FFNLNETKPRGKFTYDAVYCCNEHECHHRYAELYVIDVNINISCETDGYLTKMTCRWS
TSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSDGFYECIFQPIFLLSG
YTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGLLKISWEKPVFPEN
NLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDLCAVYAVQVRCKRLDGLGYWSN
WSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKKKK"
BASE COUNT 624 a 422 c 441 g 641 t
ORIGIN
1 accttgggcg aggagttcgg agcggcccca tcgcagagcc cacggccagc cgagcgcgcg
61 cgacgcaggt gcccgagccc cggcgccgcc gccatctctg ccttcggtcg agttggaccc
121 ggggatcaag gtgtacttct ctgaagtaag atgatttgtc aaaaattctg tgtggttttg
181 ttacattggg aatttattta tgtgataact gcgtttaact tgtcatatcc aattactcct
241 tggagattta agttgtcttg catgccacca aattcaacct atgactactt ccttttgcct
301 gctggactct caaagaatac ttcaaattcg aatggacatt atgagacagc tgttgaacct
361 aagtttaatt caagtggtac tcacttttct aacttatcca aaacaacttt ccactgttgc
421 tttcggagtg agcaagatag aaactgctcc ttatgtgcag acaacattga aggaaagaca
481 tttgtttcaa cagtaaattc tttagttttt caacaaatag atgcaaactg gaacatacag
541 tgctggctaa aaggagactt aaaattattc atctgttatg tggagtcatt atttaagaat
601 ctattcagga attataacta taaggtccat cttttatatg ttctgcctga agtgttagaa
661 gattcacctc tggttcccca aaaaggcagt tttcagatgg ttcactgcaa ttgcagtgtt
721 catgaatgtt gtgaatgtct tgtgcctgtg ccaacagcca aactcaacga cactctcctt
781 atgtgtttga aaatcacatc tggtggagta attttccagt cacctctaat gtcagttcag
841 cccataaata tggtgaagcc tgatccacca ttaggtttgc atatggaaat cacagatgat
901 ggtaatttaa agatttcttg gtccagccca ccattggtac catttccact tcaatatcaa
961 gtgaaatatt cagagaattc tacaacagtt atcagagaag ctgacaagat tgtctcagct
1021 acatccctgc tagtagacag tatacttcct gggtcttcgt atgaggttca ggtgaggggc
1081 aagagactgg atggcccagg aatctggagt gactggagta ctcctcgtgt ctttaccaca
1141 caagatgtca tatactttcc acctaaaatt ctgacaagtg ttgggtctaa tgtttctttt
1201 cactgcatct ataagaagga aaacaagatt gttccctcaa aagagattgt ttggtggatg
1261 aatttagctg agaaaattcc tcaaagccag tatgatgttg tgagtgataa tgttagcaaa
1321 gttacttttt tcaatctgaa tgaaaccaaa cctcgaggaa agtttaccta tgatgcagtg
1381 tactgctgca atgaacatga atgccatcat cgctatgctg aattatatgt gattgatgtc
1441 aatatcaata tctcatgtga aactgatggg tacttaacta aaatgacttg cagatggtca
1501 accagtacaa tccagtcact tgcggaaagc actttgcaat tgaggtatca taggagcagc
1561 ctttactgtt ctgatattcc atctattcat cccatatctg agcccaaaga ttgctatttg
1621 cagagtgatg gtttttatga atgcattttc cagccaatct tcctattatc tggctacaca
1681 atgtggatta ggatcaatca ctctctaggt tcacttgact ctccaccaac atgtgtcctt
1741 cctgattctg tggtgaagcc actgcctcca tccagtgtga aagcagaaat tactataaac
1801 attggattat tgaaaatatc ttgggaaaag ccagtctttc cagagaataa ccttcaattc
1861 cagattcgct atggtttaag tggaaaagaa gtacaatgga agatgtatga ggtttatgat
1921 gcaaaatcaa aatctgtcag tctcccagtt ccagacttgt gtgcagtcta tgctgttcag
1981 gtgcgctgta agaggctaga tggactggga tattggagta attggagcaa tccagcctac
2041 acagttgtca tggatataaa agttcctatg agaggacctg aattttggag aataattaat
2101 ggagatacta tgaaaaaaaa aaaaaaaa
//