LOCUS BC030702 2940 bp mRNA linear HUM 04-DEC-2007
DEFINITION Homo sapiens microcephalin 1, mRNA (cDNA clone MGC:26928
IMAGE:4838618), complete cds.
ACCESSION BC030702
VERSION BC030702.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2940)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2940)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (24-MAY-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 34 Row: o Column: 12
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 13375792.
FEATURES Location/Qualifiers
source 1..2940
/db_xref="H-InvDB:HIT000041111"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:26928 IMAGE:4838618"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..2940
/gene="MCPH1"
/gene_synonym="BRIT1"
/gene_synonym="MCT"
/db_xref="GeneID:79648"
/db_xref="HGNC:HGNC:6954"
/db_xref="MIM:607117"
CDS 74..1906
/gene="MCPH1"
/gene_synonym="BRIT1"
/gene_synonym="MCT"
/codon_start=1
/product="MCPH1 protein"
/protein_id="AAH30702.2"
/db_xref="GeneID:79648"
/db_xref="HGNC:HGNC:6954"
/db_xref="MIM:607117"
/translation="MAAPILKDVVAYVEVWSSNGTENYSKTFTTQLVDMGAKVSKTFN
KQVTHVIFKDGYQSTWDKAQKRGVKLVSVLWVEKCRTAGAHIDESLFPAANMNEHLSS
LIKKKRKCMQPKDFNFKTPENDKRFQKKFEKMAKELQRQKTNLDDDVPILLFESNGSL
IYTPTIEINSSHHSAMEKRLQEMKEKRENLSPTSSQMIQQSHDNPSNSLCEAPLNISR
DTLCSDEYFAGGLHSSFDDLCGNSGCGNQERKLEGSINDIKSDVCISSLVLKANNIHS
SPSFTHLDKSSPQKFLSNLSKEEINLQRNIAGKVVTPHQKQAAGMSQETFEEKYRLSP
TLSSTKGHLLIHSRPRSSSVKRKRVSHGSHSPPKEKCKRKRSTRRSIMPRLQLCRSEG
RLQHVAGPALEALSCGESSYDDYFSPDNLKERYSENLPPESQLPSSPAQLSCRSLSKK
ERTSIFEMSDFSCVGKKTRTVDITNFTAKTISSPRKTGNGEGRATSSCVTSAPEEALR
CCRQAGKEDACPEGNGFSYTIEDPALPKGHDDDLTPLEGSLEEMKEAVGLKSTQNKGT
TSKISNSSEGEAQSEHEPCFIVDCNMETSTEEKENLPGGYSGSM"
BASE COUNT 970 a 554 c 585 g 831 t
ORIGIN
1 agcggagtgc ccgcgcgcgc cgccaggctc gcaagcaccg cgtaggccag ctggccggat
61 cccgccgtct gtcatggcgg cccccatcct gaaagatgta gtggcctatg ttgaagtgtg
121 gtcatccaat ggaacagaaa attattcaaa gacatttaca acacagcttg tggatatggg
181 ggcaaaggtt tcaaaaactt ttaacaaaca agtaactcac gttatcttca aagatggcta
241 ccagagcact tgggacaaag ctcagaagag aggcgtaaag ctcgtttcgg tgctctgggt
301 tgaaaaatgc aggacagctg gagcacacat tgatgaatca ttgttccctg cagctaatat
361 gaatgaacac ttatcaagcc taattaaaaa aaaacgtaaa tgtatgcagc ccaaggattt
421 taattttaaa acaccagaaa atgataagag atttcagaag aaatttgaga aaatggctaa
481 agagctacaa aggcaaaaaa caaatctaga tgatgatgta cctattctct tatttgaatc
541 taatggttca ttaatatata ctcccacaat tgaaattaat agtagtcacc acagcgcaat
601 ggagaagaga ttacaagaga tgaaggagaa aagggaaaat ctttccccca cctcttccca
661 aatgattcag cagtctcatg ataatccaag taactctctg tgtgaagcac ctttgaacat
721 ttcacgtgat actttgtgtt cagatgaata ctttgctggt ggcttacact catcttttga
781 tgatctttgt ggaaactcag gatgtggaaa tcaggaaagg aagttggaag gatccattaa
841 tgacattaaa agtgatgtgt gtatttcttc acttgtattg aaagcaaata atattcattc
901 atcaccatct ttcactcacc tcgataaatc aagtcctcag aaatttctga gtaatctttc
961 aaaggaagaa ataaacttgc aaagaaatat tgcaggtaaa gtagtcaccc ctcaccaaaa
1021 gcaggctgca ggtatgtctc aggagacgtt tgaagagaag tatcgtttgt ctcctacctt
1081 atcttcaaca aaaggccacc ttttgataca ttcaagaccc aggagttcct cagtaaagag
1141 aaaaagagta tcacatggct cccattcacc tccgaaggaa aaatgcaaga gaaagaggag
1201 caccaggaga tctatcatgc cgaggctgca gctgtgcagg tcggaaggca ggctgcagca
1261 cgtggcggga cctgccctgg aggctcttag ctgtggggag tcttcatatg atgactattt
1321 ttcacctgat aatcttaagg aaaggtattc agagaatctt cctcctgaat ctcagctgcc
1381 atcaagccct gctcagttga gctgcagaag tctttctaag aaggagagaa caagcatatt
1441 tgaaatgtct gatttttcct gcgttggcaa aaaaaccaga acagttgaca ttaccaattt
1501 cacagcaaaa accatctcca gtcctcggaa aactggaaat ggtgaaggcc gtgcaacttc
1561 gagttgcgtg acttctgccc ctgaagaagc cctaaggtgt tgtagacagg ctgggaaaga
1621 agacgcatgc ccagagggaa atggcttttc ttacaccatt gaggaccctg ctcttccaaa
1681 aggacatgat gatgatttaa ctcctttgga aggaagcctt gaagaaatga aagaagcggt
1741 tggtctgaaa agcacacaga acaaaggtac cacttccaaa atatcaaact cctctgaagg
1801 cgaagcccag agtgaacatg agccatgttt tatagttgac tgtaacatgg agacgtctac
1861 agaagagaag gaaaacttac ccggaggata cagtggaagt atgtgaatct ccttttccaa
1921 gtcaccttcg ctaaataaac atgtaacagt gcatccatat tttaaattta tcacaacttt
1981 ttcataactt atttccccat ttactcctct ttttacttaa agaatgtgca tttgatcatt
2041 ccaatgataa actctttagg aatagatgac ttgctgtctt gtggaacttc tagacttatt
2101 ggttaagtct gttaggaatc tatttctcca agacttttcc ttcttatagg tcaaaaggat
2161 aagtagtcca tagtatgaat aactgagggg agtgaagtct ttttccttat tccattggag
2221 tcttggcgct gcagcgtgtg taaagatgta tacgatagag agtattttaa aacctaggtt
2281 cttaatagtg aggctattta aagaaagaaa ttaaggtaga ttaagccatc gattgtatca
2341 aagagaaagt gtgaaaaact acttttagaa atctgttgtc aatattgatt tttgaagaaa
2401 ctttggtcag tgttaactat gaagaaacat ttaaacattt ttgctcattt gtaacaagcc
2461 ttgtttaact tgtacttatt ttgcttgaag catcacttga aaaggtttac tcctattcat
2521 aatttaattg taattataat aaaccatatc attttattaa aagtcaaaac aataaaaaat
2581 tttgcacttc acagttataa gcacaaatag gttccagcaa ccaaaaattg aagaaatctt
2641 gaactttgac cgtctttacc taaagattag gttaaaattt gagtgagaat gcattctctc
2701 tgcatgattt ctctgctcta caaatgtttt aactgcctct ttgaaggtgg agaagtcatg
2761 gtagcgtttg aaatcatcac agacatgtta catacctttt ccttgagtat acgctcccca
2821 aaattgtttc acaaaaagaa tgaaaataat tttatgtttt tggcctgcta tttatatctt
2881 ggctttctga acatatatta aatttgacaa gaaactgtaa aaataaaaaa aaaaaaaaaa
//