LOCUS BC030230 1956 bp mRNA linear HUM 09-JUN-2008
DEFINITION Homo sapiens aminolevulinate, delta-, synthase 2, mRNA (cDNA clone
MGC:34520 IMAGE:5226194), complete cds.
ACCESSION BC030230
VERSION BC030230.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1956)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1956)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (07-MAY-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 25, 2003 this sequence version replaced BC030230.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 49 Row: n Column: 14
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4557298.
FEATURES Location/Qualifiers
source 1..1956
/db_xref="H-InvDB:HIT000040989"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:34520 IMAGE:5226194"
/tissue_type="Pancreas, Spleen, adult pooled"
/clone_lib="NIH_MGC_120"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1956
/gene="ALAS2"
/gene_synonym="ANH1"
/gene_synonym="XLSA"
/db_xref="GeneID:212"
/db_xref="HGNC:HGNC:397"
/db_xref="MIM:301300"
CDS 53..1777
/gene="ALAS2"
/gene_synonym="ANH1"
/gene_synonym="XLSA"
/codon_start=1
/product="aminolevulinate, delta-, synthase 2"
/protein_id="AAH30230.2"
/db_xref="GeneID:212"
/db_xref="HGNC:HGNC:397"
/db_xref="MIM:301300"
/translation="MRGGEVALGWNKKKRLFCEDFRFKMVTAAMLLQCCPVLARGPTS
LLGKVVKTHQFLFGIGRCPILATQGPNCSQIHLKATKAGGDSPSWAKGHCPFMLSELQ
DGKSKIVQKAAPEVQEDVKAFKTGNYVFSYDQFFRDKIMEKKQDHTYRVFKTVNRWAD
AYPFAQHFSEASVASKDVSVWCSNDYLGMSRHPQVLQATQETLQRHGVGAGGTRNISG
TSKFHVELEQELAELHQKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMI
QGIRNSGAAKFVFRHNDPDHLKKLLEKSNPKIPKIVAFETVHSMDGAICPLEELCDVS
HQYGALTFVDEVHAVGLYGSRGAGIGERDGIMHKIDIISGTLGKAFGCVGGYIASTRD
LVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMD
RGLPVIPCPSHIIPIRVGNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEELLRLAPS
PHHSPQMMEDFVEKLLLAWTAVGLPLQDVSVAACNFCRRPVHFELMSEWERSYFGNMG
PQYVTTYA"
BASE COUNT 473 a 534 c 508 g 441 t
ORIGIN
1 agggcccaca tgccttggcc ccacatacca acccaggctg ctgtgacagc ccatgagagg
61 gggagaggtt gctctgggat ggaacaagaa aaagaggttg ttttgtgagg actttaggtt
121 caagatggtg actgcagcca tgctgctaca gtgctgccca gtgcttgccc ggggccccac
181 aagcctccta ggcaaggtgg ttaagactca ccagttcctg tttggtattg gacgctgtcc
241 catcctggct acccaaggac caaactgttc tcaaatccac cttaaggcaa caaaggctgg
301 aggagattct ccatcttggg cgaagggcca ctgtcccttc atgctgtcgg aactccagga
361 tgggaagagc aagattgtgc agaaggcagc cccagaagtc caggaagatg tgaaggcttt
421 caagacagga aactatgtct tcagttatga ccagtttttc agggacaaga tcatggagaa
481 gaaacaggat cacacctacc gtgtgttcaa gactgtgaac cgctgggctg atgcatatcc
541 ctttgcccaa catttctctg aggcatctgt ggcctcaaag gatgtgtccg tctggtgtag
601 taatgattac ctgggcatga gccgacaccc tcaggtcttg caagccacac aggagaccct
661 gcagcgtcat ggtgttggag ctggtggcac ccgcaacatc tcaggcacca gtaagtttca
721 tgtggagctt gagcaggagc tggctgagct gcaccagaag gactcagccc tgctcttctc
781 ctcctgcttt gttgccaatg actctactct cttcaccttg gccaagatcc tgccagggtg
841 cgagatttac tcagacgcag gcaaccatgc ttccatgatc caaggtatcc gtaacagtgg
901 agcagccaag tttgtcttca ggcacaatga ccctgaccac ctaaagaaac ttctagagaa
961 gtctaaccct aagataccca aaattgtggc ctttgagact gtccactcca tggatggtgc
1021 catctgtccc ctcgaggagt tgtgtgatgt gtcccaccag tatggggccc tgaccttcgt
1081 ggatgaggtc catgctgtag gactgtatgg gtcccggggc gctgggattg gggagcgtga
1141 tggaattatg cataagattg acatcatctc tggaactctt ggcaaggcct ttggctgtgt
1201 gggcggctac attgccagca cccgtgactt ggtggacatg gtgcgctcct atgctgcagg
1261 cttcatcttt accacttctc tgccccccat ggtgctctct ggagctctag aatctgtgcg
1321 gctgctcaag ggagaggagg gccaagccct gaggcgagcc caccagcgca atgtcaagca
1381 catgcgccag ctactcatgg acaggggcct tcctgtcatc ccctgcccca gccacatcat
1441 ccccatccgg gtgggcaatg cagcactcaa cagcaagctc tgtgatctcc tgctctccaa
1501 gcatggcatc tatgtgcagg ccatcaacta cccaactgtc ccccggggtg aagagctcct
1561 gcgcttggca ccctcccccc accacagccc tcagatgatg gaagattttg tggagaagct
1621 gctgctggct tggactgcgg tggggctgcc cctccaggat gtgtctgtgg ctgcctgcaa
1681 tttctgtcgc cgtcctgtac actttgagct catgagtgag tgggaacgtt cctacttcgg
1741 gaacatgggg ccccagtatg tcaccaccta tgcctgagaa gccagctgcc taggattcac
1801 accccacctg cgcttcactt gggtccaggc ctactcctgt cttctgcttt gttgtgtgcc
1861 tctagctgaa ttgagcctaa aaataaagca caaaccacaa caaaaaaaaa aaaaaaaaaa
1921 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa
//