LOCUS BC030198 2314 bp mRNA linear HUM 06-OCT-2003
DEFINITION Homo sapiens integrin, alpha 9, mRNA (cDNA clone MGC:34652
IMAGE:5199296), complete cds.
ACCESSION BC030198
VERSION BC030198.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2314)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2314)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (07-MAY-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 49 Row: a Column: 14.
FEATURES Location/Qualifiers
source 1..2314
/db_xref="H-InvDB:HIT000040976"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:34652 IMAGE:5199296"
/tissue_type="Brain, adult, 6 pooled whole brains"
/clone_lib="NIH_MGC_114"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2314
/gene="ITGA9"
/gene_synonym="ALPHA-RLC"
/gene_synonym="ITGA4L"
/gene_synonym="RLC"
/db_xref="GeneID:3680"
/db_xref="MIM:603963"
CDS 261..2159
/gene="ITGA9"
/gene_synonym="ALPHA-RLC"
/gene_synonym="ITGA4L"
/gene_synonym="RLC"
/codon_start=1
/product="ITGA9 protein"
/protein_id="AAH30198.1"
/db_xref="GeneID:3680"
/db_xref="MIM:603963"
/translation="MGGPAAPRGAGRLRALLLALVVAGIPAGAYNLDPQRPVHFQGPA
DSFFGYAVLEHFHDNTRWVLVGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDM
ARGKNRGTSCGKTCREDRDDEWMGVSLARQPKADGRVLACAHRWKNIYYEADHILPHG
FCYIIPSNLQAKGRTLIPCYEEYKKKYGEEHGSCQAGIAGFFTEELVVMGAPGSFYWA
GTIKVLNLTDNTYLKLNDEVIMNRRYTYLGYAVTAGHFSHPSTIDVVGGAPQDKGIGK
VYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFSEIRDE
GQVTVYINRGNGALEEQLALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKEDDF
AGAVYIYHGDAGGIVPQYSMKLSGQKINPVLRMFGQSISGGIDMDGNGYPDVTVGAFM
SDSVVLLRARPVITVDVSIFLPGSINITAPQCHDGQQPVNCLNVTTCFSFHGKHVPEE
IGLNYVLMADVAKKEKGQMPRVYFVLLGETMGQVTEKLQLTYMEETCRHYVAHVKRRV
QDVISPIVFEAAYSLSEHVTGEEERELPPLTPVLRWKKGQKIAQKNQVRTLKLILSTQ
GGSCTEQK"
misc_feature 1158..1313
/gene="ITGA9"
/gene_synonym="ALPHA-RLC"
/gene_synonym="ITGA4L"
/gene_synonym="RLC"
/note="Int_alpha; Region: Integrin alpha (beta-propellor
repeats). Integrins are cell adhesion molecules that
mediate cell-extracellular matrix and cell-cell
interactions. They contain both alpha and beta subunits.
Alpha integrins are proposed to contain a domain
containing a 7-fold repeat that adopts a beta-propellor
fold. Some of these domains contain an inserted von
Willebrand factor type-A domain. Some repeats contain
putative calcium-binding sites. The 7-fold repeat domain
is homologous to a similar domain in
phosphatidylinositol-glycan-specific phospholipase D"
/db_xref="CDD:smart00191"
misc_feature 1341..1475
/gene="ITGA9"
/gene_synonym="ALPHA-RLC"
/gene_synonym="ITGA4L"
/gene_synonym="RLC"
/note="Int_alpha; Region: Integrin alpha (beta-propellor
repeats). Integrins are cell adhesion molecules that
mediate cell-extracellular matrix and cell-cell
interactions. They contain both alpha and beta subunits.
Alpha integrins are proposed to contain a domain
containing a 7-fold repeat that adopts a beta-propellor
fold. Some of these domains contain an inserted von
Willebrand factor type-A domain. Some repeats contain
putative calcium-binding sites. The 7-fold repeat domain
is homologous to a similar domain in
phosphatidylinositol-glycan-specific phospholipase D"
/db_xref="CDD:smart00191"
misc_feature 1533..1694
/gene="ITGA9"
/gene_synonym="ALPHA-RLC"
/gene_synonym="ITGA4L"
/gene_synonym="RLC"
/note="Int_alpha; Region: Integrin alpha (beta-propellor
repeats). Integrins are cell adhesion molecules that
mediate cell-extracellular matrix and cell-cell
interactions. They contain both alpha and beta subunits.
Alpha integrins are proposed to contain a domain
containing a 7-fold repeat that adopts a beta-propellor
fold. Some of these domains contain an inserted von
Willebrand factor type-A domain. Some repeats contain
putative calcium-binding sites. The 7-fold repeat domain
is homologous to a similar domain in
phosphatidylinositol-glycan-specific phospholipase D"
/db_xref="CDD:smart00191"
BASE COUNT 520 a 651 c 694 g 449 t
ORIGIN
1 ccgcccggcc cgggacccgc tcgcgcagac ttctcgggcg gactgaggac gccgccgctc
61 ggggccgccc ctgtgctcgc cttcagcgcc cgctcagccc gccgtccgcg ccccggtggc
121 gggcccgacg cccgcattcc gcccgtgtcc aggcgcagag ctcccgcccc ggggagcttc
181 ctggccgtcg gcgggccccg cggcccgcgc gctcggcgcc ctgctcgccg ggcagagggg
241 aaggcggcgg ccggctgggg atgggcggcc cggctgcgcc gaggggcgcc gggaggctcc
301 gcgcgctgct gctggcgctg gtggtcgcgg ggatccccgc gggcgcctac aacctcgacc
361 cgcagcgccc cgtgcacttc cagggccccg ctgactcgtt cttcggctac gcagttctgg
421 agcatttcca cgacaacacg cgctgggtcc ttgtgggcgc accaaaggca gattccaaat
481 acagcccttc agtgaagtct cctggggctg tgtttaagtg ccgtgttcac accaaccctg
541 accggagatg caccgaactg gacatggctc gagggaagaa tcggggcacg tcctgcggaa
601 agacctgccg ggaagaccgc gatgatgagt ggatgggggt gagcctggcc cgacagccca
661 aggctgatgg ccgtgtgttg gcctgtgctc atcgctggaa gaacatctac tatgaagccg
721 accacatcct accccatggc ttctgctaca tcatcccctc caacctccag gccaaaggca
781 ggacgctgat cccttgctat gaagagtata agaagaagta cggagaggaa cacggctcct
841 gccaggctgg gatagcgggc ttcttcaccg aggagctggt ggtgatgggt gctccagggt
901 cattttattg ggctggaacc atcaaagtgc tgaaccttac ggacaacacc tatttaaaac
961 tgaacgacga agtgatcatg aacaggcggt acacctacct gggctacgca gtgaccgctg
1021 gccacttctc tcacccgtcc accattgatg tggtaggagg tgccccacag gacaaaggca
1081 tcggcaaggt ttatattttc agagctgacc gaagatcagg caccttaatt aagatctttc
1141 aagcatcagg taaaaagatg ggctcttact tcggctcctc cttgtgcgca gttgacctga
1201 atggggacgg cctctctgac ctgctggtgg gggcccccat gttttctgag atcagggatg
1261 agggacaggt cactgtctac atcaacagag gaaatggagc cctcgaggag cagctggctc
1321 tgactgggga tggtgcctac aatgcgcact ttggagagag cattgccagc ctggacgatc
1381 tggacaatga tgggttccca gatgtggcca ttggtgcacc caaggaggat gacttcgcag
1441 gggcggtcta tatctatcat ggtgatgccg gtgggatagt ccctcagtac tcaatgaaac
1501 tgtctgggca gaagataaat ccagtgctcc ggatgtttgg tcagtccata tcgggaggca
1561 ttgatatgga tggaaatggc tatcctgatg tcactgttgg agccttcatg tccgacagcg
1621 tggttcttct cagagcaagg cctgtcatta cggtggatgt ctccatcttc ctcccgggct
1681 ccatcaacat cacagcgcct cagtgtcacg acggacagca gcctgtgaac tgcctgaacg
1741 tcaccacctg cttcagcttc catggcaaac acgttccaga agagattggc ctgaattatg
1801 ttctgatggc tgacgtggcc aaaaaggaga agggccagat gcccagggtc tactttgtgc
1861 tgctgggaga gaccatgggt caggtcacag agaagctgca gctgacttac atggaggaga
1921 cgtgtcgtca ctatgtggcc catgtgaagc ggagggtgca ggacgtcatc agcccgatcg
1981 tgtttgaagc agcctacagc ctcagtgagc atgtgactgg agaggaggag agggaactgc
2041 cgcctctgac accagttctc cgctggaaaa agggacaaaa gattgcccaa aagaatcagg
2101 tcagaacctt aaagctcata ctcagcaccc aaggtggcag ctgcacagag cagaaataat
2161 ggcccaaaag ttgagagagc cgtgggcctg gctgctcagg agaccgcagc caggacacac
2221 ctcctctctg ggtctccctt ttctgatctg caaaatgata aaataaacag tcttaggggt
2281 taaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa
//